Animals are currently used where there is no scientifically satisfactory alternative, but there has been considerable progress in developing new methodologies that could replace the use of animals in ...

The LAG-R framework (Laboratory Animal Genetic Reporting) is a set of guidelines to support more complete documentation of the genetic make-up of animals of all species that are used in research, with...

We connect researchers with specialists in diverse model systems to support innovation and refinement.

The LAG-R framework (Laboratory Animal Genetic Reporting) is a set of guidelines to support more complete documentation of the genetic make-up of animals of all species that are used in research, with...

Submit an application to have your free, novel, genetically altered mouse model generated by the Mary Lyon Centre

Researchers at Newcastle University are using a conditional mouse mutant made by the Mary Lyon Centre’s Genome Editing Mice for Medicine (GEMM) programme to study the role of an ultra-conserved exon in the splicing regulator gene Tra2b. Many genes function as instructions for producing proteins, which perform the majority of tasks within our cells. To […]