iiinova — where your digital self keeps evolving

Luke Johnson @lukejohns.online · 02/10/2026

Where can I lodge a complaint against the inexorable passage of time

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Luke Johnson @lukejohns.online · 02/10/2026

RE: fedi.lukejohns.online/@luke/1172138… Again? Seriously?? Someone really needs to do something about this

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Reposted by Luke Johnson

Cambridge Day @cambridgeday.com · 26/09/2026

Cambridge’s worst intersections getting safety makeovers “High Crash Locations” are the target of a new effort by the Department of Transportation, starting with three between MIT and Central Square....

cambridgeday.com

Cambridge’s worst intersections getting safety makeovers

“High Crash Locations” are the target of a new effort by the Department of Transportation, starting with three between MIT and Central Square.

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Luke Johnson @lukejohns.online · 15/09/2026

#boston #safestreets Haviland Street is a horrible rat run and should have modal filters to prevent these kind of impatient drivers cutting down there without looking.

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Luke Johnson @lukejohns.online · 15/09/2026

Near miss today at Mass Ave and Haviland St reminded me that: 1. I really need new brake pads, and 2. Mayor Wu is a massive safe streets disappointment #massbike #boston #safestreets

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Luke Johnson @lukejohns.online · 05/09/2026

RE: fitpub.social/activities/4fc06bbe-3… The train I was racing got to Park Street just before me, but on the day (a Friday evening) there could be more traffic and passengers slowing the train down 🤞 rundirtywater.com/charlie

fitpub.social

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Luke Johnson @lukejohns.online · 04/09/2026

If anyone is wondering whether I have new music in the pipeline, the answer is ??

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Luke Johnson @lukejohns.online · 04/09/2026

RE: fedi.lukejohns.online/@luke/1152039… Wait, it's #BandcampFriday again already? And this blog post is almost a year old?? How time flies. Take a listen for free: lukejohns.bandcamp.com/album/bits-p… You could even be my first follower!

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Reposted by Luke Johnson

Madeleine Bonsma-Fisher, PhD @mbonsma.bsky.social · 03/09/2026

The highest high: paper is finished The lowest low: paper is 90% finished

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Luke Johnson @lukejohns.online · 21/08/2026

RE: techhub.social/@jerzone/11713505346… I'm hooked, not even a minute in and we've already had "two-stroke * two cylinders = four stroke 🤓" and "OEM ziptie"

techhub.social

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Luke Johnson @lukejohns.online · 15/08/2026

RE: fitpub.social/activities/7f7c731b-f… Not the sort of thing you could do in many US cities!

fitpub.social

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Luke Johnson @lukejohns.online · 03/08/2026

Also for the very first time I've registered for something and been able to take the username "luke"...

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Luke Johnson @lukejohns.online · 03/08/2026

RE: fitpub.social/activities/6fd5c983-3… When I stopped using Strava ages ago there wasn't a replacement on the Fediverse to share activities - but now there is! I've just signed up on @fitpub and you should take a look if you haven't heard of it yet.

fitpub.social

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Luke Johnson @lukejohns.online · 10/07/2026

I haven't even been home for one day and mum's already got me haymaking

A man in faded green shorts and a flowery shirt rakes long grass into piles in a back garden. Three sacks stuffed with hay lie on the ground around him.

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Luke Johnson @lukejohns.online · 01/07/2026

There was another social dinner on the Wednesday night but I took the evening off. Time for a nice hot run around the Englischer Garten, where pretty much the whole city was cooling off in the streams.

A sunset view across the Englischer Garten in Munich, with large crowds of people walking, cycling, sunbathing and swimming in the streams.

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Luke Johnson @lukejohns.online · 01/07/2026

Also last Wednesday I got to show off my poster during the poster tour. As you can see I was obviously quite sceptical of my own results…

A very handsome man in a delightful patterned shirt stands next to an academic poster with his arms crossed. He looks vaguely worried.

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Luke Johnson @lukejohns.online · 01/07/2026

Some highlights from the rest of the day included: * Jamie Collins on how to analyze multiscale data and hierarchical structures, * Nadine Hendriks on hip joint shape trajectories during growth, and * Adam Culvenor joining remotely from Australia to talk about post-traumatic OA.

Prof Jamie Collins (Brigham & Women's Hospital, Harvard Medical School) presents the title slide for her keynote talk on "Analyzing Multidimensional Imaging Data in Osteoarthritis: Matching Methods to Questions"

A slide from Nadine Hendrik's scientific presentation on longitudinal hip shape during growth from a large population-based cohort. The slide shows methods details and examples of hip radiographs at multiple age points during growth.

A slide from a recorded keynote talk by Adam Culvenor (LaTrobe University). The slide shows results from recent studies relating post-traumatic changes in joint contact force with radiographic OA.

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Luke Johnson @lukejohns.online · 30/06/2026

PROBE reminds me a lot of OpenSAFELY but with a whole load more moving parts, so best of luck! I thought I could tag Ben Goldacre here, but he no longer appears to be bridged :(

opensafely.org

OpenSAFELY - A platform for analysing large, sensitive datasets

OpenSAFELY is a platform for analysing large, sensitive datasets – safely and securely. OpenSAFELY is built by a team at the Bennett Institute.

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Luke Johnson @lukejohns.online · 30/06/2026

We also had an update from Jos Runhaar on a new initiative called PROBE - one for all you federation freaks out there, as PROBE aims to collect disparate OA databases together into a “federated analytics” structure.

Jos Runhaar (Erasmus Medical Center, Rotterdam) presents different data federation structures (horizontal, vertical, and federated transfer learning) in an update of the first year of the PROBE initiative.

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Luke Johnson @lukejohns.online · 30/06/2026

…BUT GLP-1s might? This kicked off a big discussion throughout the meeting of: 1. what the definition of a DMOAD really is/should be, and 2. whether the effect of GLP-1 agonists is just due to weight loss or some other mechanism. As discussed in a later talk by Phil Conaghan (pictured)

Prof Phil Conaghan (University of Leeds) presents a figure from a recent RCT testing the impact of GLP-1RA drugs on osteoarthritis. Two subfigures are shown, comparing change in body weight from baseline over time in GLP-1RA and placebo groups, and change in WOMAC pain score over time in the same groups.

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Luke Johnson @lukejohns.online · 30/06/2026

I'm back with more #IWOAI posting, after a suitable recovery period... Day 2 (i.e. last Wednesday) started with a session on the past year’s clinical trials, hosted by Kent Kwoh. Still no FDA-approved DMOADs* that actually work… (* Disease Modifying Osteoarthritis Drugs)

Prof Kent Kwoh from the University of Arizona presents the latest clinical trials on osteoarthritis (image depicts the title slide of his talk).

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Luke Johnson @lukejohns.online · 25/06/2026

This was all happening back on Tuesday, by the way. I'm _very_ behind.

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Luke Johnson @lukejohns.online · 25/06/2026

…and a review of bone imaging in OA from Thomas Link, demonstrating the whole breadth of techniques. It's not just MRI!

A man presents a slide on PET and PET-MRI, with a results summary on the left and example images on the right.

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Luke Johnson @lukejohns.online · 25/06/2026

Session 2 was all about BONE, including a couple of very interesting talks from Andy Wong's group at the University of Toronto about the links between OA and osteoporosis...

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Luke Johnson @lukejohns.online · 25/06/2026

As anticipated, true live posting is beyond me. I can't do it if I want to pay attention at the same time! Instead I'll be chipping through the backlog slowly over the next few days.

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Luke Johnson @lukejohns.online · 23/06/2026

Felix Eckstein reassures us that you shouldn’t be ashamed of performing post-hoc analyses, you just have to be transparent about them #IWOAI

A man presents a slide with a big table on it breaking down different types of research (including exploratory, confirmatory and post-hoc).

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Luke Johnson @lukejohns.online · 23/06/2026

#IWOAI Day 1 started with PD Dr Wolfgang Wirth setting the tone appropriately. Not too many meetings include a whole day for a social trip!

A man presenting a slideshow, currently on a slide titled "Bavaria" and filled with images and symbols of the region. Just in case we forgot where we were.

A slide detailing the full social day that makes up part of IWOAI: a trip to lake Ammersee and the Monastery Andechs

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Luke Johnson @lukejohns.online · 23/06/2026

Let's be real folks, this was the cheapest flight available from Boston to Munich in late June with a month's notice, and you get what you pay for. I did watch North By Northwest for the first time though so that was fun.

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Luke Johnson @lukejohns.online · 23/06/2026

I didn't think I was going to be fed, but I was! I even packed sandwiches...

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Luke Johnson @lukejohns.online · 23/06/2026

First impressions: wow those seats are miserable. I wouldn't want to try and sleep in them. Thankfully because we were landing at just before my body clock's midnight that would have been pointless anyway.

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Luke Johnson @lukejohns.online · 23/06/2026

RE: fedi.lukejohns.online/@luke/1167949… So as not to interrupt the science I'll split off the flight review here. We're talking the peak of transatlantic luxury folks - Condor!

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Luke Johnson @lukejohns.online · 22/06/2026

IWOAI stands for International Workshop on Osteoarthritis Imaging by the way. A good little meeting with a big social dimension.

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Luke Johnson @lukejohns.online · 19/05/2026

Today marks the traditional first day of Boston summer (the red line has broken down because it's too hot)

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Luke Johnson @lukejohns.online · 22/04/2026

Quote: "Tesla is now worth more than the next nine largest carmakers in the world put together. ... Understanding why [Europe] doesn’t have a Tesla is existential." Interesting choice to use market cap here, particularly as they're only #11 in revenue! #WorksInProgress

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Luke Johnson @lukejohns.online · 22/04/2026

RE: fedi.lukejohns.online/@luke/1161338… Continuing my Works In Progress posting - this article is overall a good discussion of the differences in hiring and firing flexibility and how it influences how risk-averse companies are. BUT the motivating argument is, er, suspect at […]

fedi.lukejohns.online

Original post on fedi.lukejohns.online

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Luke Johnson @lukejohns.online · 20/04/2026

Marathon day in Boston 👟 Before checking, I was expecting the route to take advantage of all those big waterfront roads and take the runners past a load of landmarks, but nope - just miles and miles of suburbia!

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Luke Johnson @lukejohns.online · 08/04/2026

Now playing, while I try and knock off as much admin as possible: "Parklife" by Blur #vinyl #nowplaying

The album sleeve for "Parklife" by Blur, cover art featuring two greyhounds with muzzle cages running towards the camera during a dog race, is propped up behind an Audio-Technica "sound burger" record player playing a gold-coloured LP.

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Luke Johnson @lukejohns.online · 08/04/2026

Maybe one day I'll be walking along Huntington Ave and faintly hear a male voice choir singing "Rhyfelgyrch Gwŷr Harlech", and then the banner will be vindicated.

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Luke Johnson @lukejohns.online · 08/04/2026

After 10 months in the Boston area, I still haven't come across the prominent Welsh diaspora community. Never say never, though.

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Luke Johnson @lukejohns.online · 08/04/2026

Spotted in CHA Cambridge Hospital: one of these is not like the others! 🏴󠁧󠁢󠁷󠁬󠁳󠁿 🏴󠁧󠁢󠁷󠁬󠁳󠁿 🏴󠁧󠁢󠁷󠁬󠁳󠁿

A large blue welcome banner with the word for "welcome" translated into multiple global languages. One of which is, for some reason, Welsh.

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Luke Johnson @lukejohns.online · 01/04/2026

Here's a somewhat scummy thing that Claude does to keep you trapped in the platform: when you export a report to markdown or PDF, the reference hyperlinks aren't included! There's no technical reason for this, just keeping people tied to the service. 😤

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Luke Johnson @lukejohns.online · 25/03/2026

All-time great musical direction in Chichester Psalms #Bernstein

Musical direction for the sopranos: "(Blissfully unaware of threat)"

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Luke Johnson @lukejohns.online · 06/03/2026

2/2 I.e. instead of the current numbering system (which started in 2001), I've been given a brand new registration number using the 1963-1982 numbering scheme! I'm also allowed to get an old-style silver-on-black plate too which is neat […]

fedi.lukejohns.online

Original post on fedi.lukejohns.online

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Luke Johnson @lukejohns.online · 06/03/2026

I've just finished registering Blue (pictured) in the UK! One interesting thing: for first-time registrations of imported classic cars, the DVLA gives you a period-correct plate number. 1/2

A small blue convertible car overlooking a scenic ocean view.

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