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lukasneukomm.bsky.social

@lukasneukomm.bsky.social

Reposted by @lukasneukomm.bsky.social

Andrea Loreto @andrea-loreto.bsky.social · 18/11/2025

Happy to share our review in @natrevneuro.nature.com , written with my friend and long-time collaborator @lukasneukomm.bsky.social . We cover everything related to Programmed Axon Degeneration, from the core biology to the path toward clinical translation. @sydney.edu.au, @snowmedical.bsky.social

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lukasneukomm.bsky.social @lukasneukomm.bsky.social · 13/11/2025

An amazing collaboration with @andrea-loreto.bsky.social is finally out in @natrevneuro.nature.com. In this review, we cover all aspects of programmed axon degeneration (PAxD); from flies to humans; from basic research to clinical trials; and from associated risks to opportunities.

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Reposted by @lukasneukomm.bsky.social

Nature Reviews Neuroscience @natrevneuro.nature.com · 13/11/2025

Programmed axon degeneration: mechanism, inhibition and therapeutic potential — a Review by Andrea Loreto & Lukas J. Neukomm @andrea-loreto.bsky.social @lukasneukomm.bsky.social @sydneysavesight.bsky.social @sydney.edu.au #neuroscience #neuroskyence www.nature.com/articles/s41...

nature.com

Programmed axon degeneration: mechanism, inhibition and therapeutic potential - Nature Reviews Neuroscience

Programmed axon degeneration (PAxD) is activated by axotomy to execute the self-destruction of a severed distal axon. It may also be activated by some non-axotomy insults, suggesting it has a role in ...

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