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Loren Williams

@lorendw.bsky.social
41 followers 13 following 5 posts

I work on the ribosome, the origins of life, evolution and biological chemistry.

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Loren Williams @lorendw.bsky.social · 14/03/2025
The amazing world of protein function, from Kavita's paper.
Structures and functions of polypeptides, which has access to a seemingly infinite landscapes of functional space. All of these structures are built on self-complementarity of the backbone. What a molecule!
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Loren Williams @lorendw.bsky.social · 14/03/2025
RNA World, help. 1) Chicken & Egg: Multiple types of complex polymers (RNA and protein) cannot arise simultaneously. 2) Extant reflects ancient: extant functions of RNA are direct reflections of prebiotic behaviors. 3) Parsimony. The RNA world is simple. A simple model is a good model. Is that it?
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Loren Williams @lorendw.bsky.social · 08/03/2025
My second ever Bluesky post: Another part of the work of my wonderful graduate student Kavita Matange (post doc at CSHL) has come out here (open access). pubs.acs.org/doi/full/10....
pubs.acs.org
Biological Polymers: Evolution, Function, and Significance
ConspectusA holistic description of biopolymers and their evolutionary origins will contribute to our understanding of biochemistry, biology, the origins of life, and signatures of life outside our pl...
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Loren Williams @lorendw.bsky.social · 08/03/2025
I apologize that that paper is behind a paywall. You can access it free here: williams.chemistry.gatech.edu/publications...
williams.chemistry.gatech.edu
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Loren Williams @lorendw.bsky.social · 08/03/2025
My first ever Bluesky post: Some of the work of my wonderful graduate student Kavita Matange (now a post doc at CSHL) has just come out. www.nature.com/articles/s41...
nature.com
Evolution of complex chemical mixtures reveals combinatorial compression and population synchronicity - Nature Chemistry
Origins-of-life research has focused on specific chemical reactions that might lead to biological molecules. Now an experimental model of chemical evolution based on oscillating water activity has bee...
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