Excited to share another study from my lab @fordhamchem now out @narjournal.bsky.social: doi.org/10.1093/nar/.... Most bacterial DNA polymerases must interact with the sliding clamp DnaN for their function, but we show that it’s more complicated in B. subtilis DNA replication. (1/4)
doi.org
The B. subtilis replicative polymerases bind the sliding clamp with different strengths to tune their activity in DNA replication
Abstract. Ring-shaped sliding clamp proteins are essential components of the replication machinery across all domains of life. DNA polymerases bind the cla