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Lignani Lab

@lignanilab.bsky.social
151 followers 160 following 4 posts

UCL/ Neuroscience/ Epilepsy/ Gene therapy/ Brain Dynamics/ Dravet Syndrome/ CRISPR/ Homeostatic plasticity

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Katja Kobow @katjakobow.bsky.social · 09/10/2025
Did you know that people with #epilepsy have a significantly reduced life expectancy and an increased burden of age-related comorbidities? Our new study „Time flies faster in epilepsy“ lnkd.in/d28QCtMS looks into how biological aging contributes to the disease.
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Reposted by Lignani Lab
UCL Faculty of Brain Sciences @uclbrainscience.bsky.social · 22/07/2025
Today is #WorldBrainDay, a global campaign promoting brain health for all ages. At UCL, we're spotlighting some of the groundbreaking research that's shaping the future of brain health and wellbeing. 🧵
Reads: World Brain Day
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UCL Faculty of Brain Sciences @uclbrainscience.bsky.social · 22/07/2025
2/ Prof Gabriele Lignani of @lignanilab.bsky.social is leading an international team of researchers to develop a new generation of cell-state gene therapies for neuropsychiatric disorders. www.ucl.ac.uk/brain-scienc...
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Professor Gabriele Lignani on developing new gene therapies for neuropsychiatric disorders
Professor Gabriele Lignani is leading an international team of researchers to develop a new generation of cell-state gene therapies for neuropsychiatric disorders
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Reposted by Lignani Lab
Clara Zourray she/her @clarazourray.bsky.social · 16/05/2025
Very excited to share my (first 😁) first-author preprint from my PhD work with @lignanilab.bsky.social 🎉 We uncovered an unexpected role for Nav1.1 in early cortical development, notably in the regulation of the cell cycle in cortical progenitors. www.researchsquare.com/article/rs-6...
researchsquare.com
Prenatal sodium channel dysfunction in Dravet syndrome alters cortical development
Neurodevelopmental disorders associated with epilepsy are typically linked to postnatal dysfunction of synaptic proteins and ion channels, yet increasing evidence suggests a role for these proteins be...
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Lignani Lab @lignanilab.bsky.social · 16/05/2025
Thrilled to share that our latest work on #DravetSyndrome is now out as a preprint! 🚀 This project, brilliantly led by @clarazourray.bsky.social and co-supervised by Serena Barral, brought together an incredible team. A huge thanks to everyone involved, exciting science ahead! 👏 shorturl.at/NdC79
researchsquare.com
Prenatal sodium channel dysfunction in Dravet syndrome alters cortical development
Neurodevelopmental disorders associated with epilepsy are typically linked to postnatal dysfunction of synaptic proteins and ion channels, yet increasing evidence suggests a role for these proteins be...
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Reposted by Lignani Lab
UCL Faculty of Brain Sciences @uclbrainscience.bsky.social · 21/01/2025
UCL researchers will receive £8.1m in @aria-research.bsky.social funding to embark on cutting edge research to help overcome neurodegenerative diseases. @uclpals.bsky.social @uclqsion.bsky.social bit.ly/4g9MN1H
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UCL researchers receive £8.1 million ARIA funding for innovative brain research
UCL researchers will receive £8.1m in funding to embark on cutting edge research to help overcome neurodegenerative diseases.
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Lignani Lab @lignanilab.bsky.social · 20/01/2025
Thrilled to announce that our international team has been awarded a prestigious research grant! Together, we aim to tackle some of the most complex neurological diseases using cutting-edge technologies. Excited for the journey ahead! @aria-research.bsky.social @ucl.ac.uk @uclqsion.bsky.social
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Lignani Lab @lignanilab.bsky.social · 06/01/2025
Deadline extend to 19th January!
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Dr Karolina Farrell @karolinafarrell.bsky.social · 20/12/2024
We're hiring! 🧠 We're looking for a postdoc to perform neuropixels recordings in mouse models of neurological disorders as part of a larger team that's testing out novel gene therapies here at UCL. Super exciting project, come join the team! tinyurl.com/2ykfy2um #neuroskyence #neurojobs
Photograph of the Institute of Neurology, University College London in Queen Square.
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Lignani Lab @lignanilab.bsky.social · 24/12/2024
📢 We are looking for a dynamic, energetic and passionate postdoc fellow to work on in vivo electrophysiology to understand and treat neurological diseases! Deadline 8th January #neuropixels #braindynamics #epilepsy #neurodiseases tinyurl.com/5n6sad38
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