iiinova — where your digital self keeps evolving

Leona Chitoiu

@leona-chitoiu.bsky.social

84 followers 227 following 0 posts

PhD Student in Structural Biology @imprs-ml.bsky.social @BeckmannLab.bsky.social

Posts Replies Media

Reposted by Leona Chitoiu

Beckmann Lab @beckmannlab.bsky.social · 14/09/2026

New preprint! 👀RNAse activity has to be tightly regulated.✂️🧬Here, we present the dynamic architecture of the conserved Rixosome complex – a major player in ribosome maturation and heterochromatin maintenance. Our results give insights into its mode of activation.👇 #cryoEM #Ribosome #RNA

13516

Reposted by Leona Chitoiu

Beckmann Lab @beckmannlab.bsky.social · 10/09/2026

📰Happy to share our preprint.🥳Here we investigate🔬, the essential role of the conserved RNA helicase Drs1. We show that its engagement and activity license timely incorporation of 25S rRNA domain III into maturing nucleolar pre-60S subunits.👇 doi.org/10.64898/2026.09.05.749353 #cryoEM #ribosome #RNA

12316

Reposted by Leona Chitoiu

Beckmann Lab @beckmannlab.bsky.social · 01/09/2026

Preprint alert: a helicase watching the ribosomal A-site 👀🧬 Our cryo-EM structure reveals how yeast Dhx29 senses mRNA hairpins forming in the A-site and positions its helicase at the mRNA entry channel to resolve them during translation elongation: doi.org/10.64898/202... #cryoEM #ribosome #RNA

24823

Reposted by Leona Chitoiu

Beckmann Lab @beckmannlab.bsky.social · 22/03/2026

Proud to share our latest preprint! 🥳 Using a multidisciplinary approach, we uncover a dual function of the snR37 H/ACA snoRNP - combining pseudouridylation with ribosome chaperone activity within a single RNP.🔬🧬 Challenging the traditional view of snoRNP function. 👇 #cryoEM #ribosome #RNA #snoRNA

biorxiv.org

2259

Reposted by Leona Chitoiu

Beckmann Lab @beckmannlab.bsky.social · 23/11/2025

How does the kinase ZAK sense ribosome collisions? Find out in our latest collaboration with the @greenlab.bsky.social @doubleshuang.bsky.social @Vienna Huso: 1/4 rdcu.be/eRmJl #ribosome #cryoEM #LMU #JHMI

24920