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Jessica Lehoczky

@lehoczky-lab.bsky.social

115 followers 96 following 2 posts

Regenerative medicine/developmental biology/mouse genetics; Harvard Medical School/BWH Orthopedics

Posts Replies Media

Jessica Lehoczky @lehoczky-lab.bsky.social · 08/01/2026

It’s finally out!! Congrats @vivijou.bsky.social www.science.org/doi/10.1126/...

science.org

Mouse digit AAV gene delivery into fibroblasts regulates regenerative outcome

AAV delivery of putative proregenerative genes into proximal, nonregenerative mouse digit fibroblasts induces regeneration.

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Jessica Lehoczky @lehoczky-lab.bsky.social · 23/04/2025

Congratulations to Vivian who is now officially Dr. Jou!!! @vivijou.bsky.social Check out our newest preprint showcasing the AAV delivery technique Vivian developed for the mouse digit. Spoiler alert: she shows AAV delivery of single candidate genes can modulate fibrosis and regeneration!

biorxiv.org

Mouse digit AAV gene delivery into fibroblasts regulates regenerative outcome

The distal mouse digit tip regenerates post-amputation, while the proximal digit undergoes fibrosis. This study presents a comparative single-cell RNA sequencing-based analysis of regenerating and non...

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Reposted by Jessica Lehoczky

Igor Schneider @ischneider.bsky.social · 15/03/2025

Our preprint is out! Kudos to @josanesousa.bsky.social, @gabrielalima19.bsky.social, @perezlouise.bsky.social and undergraduate prodigy Hannah Shof! By comparing Polypterus fin and axolotl limb we find shared and new regeneration programs. @lsuscience.bsky.social www.biorxiv.org/content/10.1...

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Reposted by Jessica Lehoczky

Michalis Averof @michalis-averof.bsky.social · 28/02/2025

Do you have experience in generating transgenic tools and fluorescent markers? Are you interested in developing new tools in a non-conventional model, to observe and genetically manipulate cells during leg regeneration? We are recruiting! www.averof-lab.org/pages/3560

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Reposted by Jessica Lehoczky

International Society for Regenerative Biology @isrbio.bsky.social · 09/01/2025

Interested in regeneration? Consider joining the ISRB community! Details below.

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