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Lead-DBS

@lead-dbs.org
560 followers 30 following 117 posts

Open source toolbox to model deep brain stimulation electrodes in the human brain. www.lead-dbs.org - home at the @netstim.org

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Lead-DBS @lead-dbs.org · 19/09/2026
New publication using Lead-DBS: In this article by Hanafi et al., the authors tested gait-adaptation kinematics, EEG, and FDG‑PET in Parkinson's patients during virtual obstacle avoidance with active versus paused STN‑DBS and... Check out the paper here 👇👇 doi.org/10.1016/j.brs.2026.103207
Title card for publication: Subthalamic DBS Engages Right-lateralized Frontal Control to Improve Gait Adaptation in Parkinson’s Disease
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Lead-DBS @lead-dbs.org · 12/09/2026
New publication using Lead-DBS: In this article by Kist et al., patients with OCD treated with subthalamic deep brain stimulation performed visual detection and confidence judgments with EEG, showing intact detection but poor... Check out the paper here 👇👇 doi.org/10.1038/s41398-026-04423-6
Title card for publication: Assessing the effect of subthalamic stimulation on metaperception in obsessive-compulsive disorder
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Lead-DBS @lead-dbs.org · 11/09/2026
New publication using Lead-DBS: In this article by Singh et al., a three‑center retrospective study of 22 patients with drug‑resistant insular epilepsy treated with responsive neurostimulation or chronic subthreshold stimulation repor... Check out the paper here 👇👇 doi.org/10.1002/epi.70479
Title card for publication: Invasive network neuromodulation for insular epilepsy: A three-center retrospective study
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Lead-DBS @lead-dbs.org · 10/09/2026
New publication using Lead-DBS: In this article by Huang et al., the authors mapped pain-related networks using rapid stereo-EEG to enable personalized multinodal stimulation for refractory facial pain. Check out the paper here 👇👇 doi.org/10.1016/j.brs.2026.103176
Title card for publication: Rapid stereo-EEG network mapping enables personalized multinodal stimulation for refractory facial pain
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Lead-DBS @lead-dbs.org · 09/09/2026
New publication using Lead-DBS: In this article by Meyer et al., the authors tested in 19 Parkinson’s patients whether subthalamic deep brain stimulation modulates automatic response inhibition and showed that stimulation spe... Check out the paper here 👇👇 doi.org/10.1093/braincomms/fcag325
Title card for publication: Hyperdirect projections from the supplementary motor area mediate subthalamic stimulation effects on movement initiation and inhibition in Parkinson’s disease
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Lead-DBS @lead-dbs.org · 08/09/2026
New publication using Lead-DBS: In this article by Dary et al., they tested whether circadian modulation of aperiodic and oscillatory intracranial EEG could serve as a biomarker of seizure burden in 19 patients with Lennox–Gastaut syn... Check out the paper here 👇👇 doi.org/10.1002/epi.70457
Title card for publication: Circadian modulation of aperiodic background and oscillatory activity as a biomarker of seizure burden in Lennox-Gastaut syndrome
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Lead-DBS @lead-dbs.org · 07/09/2026
New publication using Lead-DBS: In this article by Liu et al., the authors tested direct substantia nigra DBS in Parkinson's disease at 10, 30, and 130 Hz, observed a frequency-dependent acute motor and stride-length benefit w... Check out the paper here 👇👇 doi.org/10.1016/j.brs.2026.103186
Title card for publication: Direct Substantia Nigra Deep Brain Stimulation in Parkinson’s Disease: Efficacy, Safety, and the Frequency-Response Relationship
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Lead-DBS @lead-dbs.org · 06/09/2026
New publication using Lead-DBS: In this article by Goede et al., the authors used DBS network mapping across multiple patient cohorts to show that rest tremor and action tremor map to distinct subnetworks within the primary... Check out the paper here 👇👇 doi.org/10.1016/j.celrep.2026.117404
Title card for publication: Action and rest tremor map to distinct networks within the primary motor cortex
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Lead-DBS @lead-dbs.org · 24/08/2026
Classic publication using Lead-DBS: In this article by Wilkins et al., the authors tested whether swing time variability is a behavioral marker of cortical cholinergic integrity in Parkinson's disease and... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Gait variability is linked to the atrophy of the Nucleus Basalis of Meynert and is resistant to STN DBS in Parkinson's disease
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Lead-DBS @lead-dbs.org · 23/08/2026
New publication using Lead-DBS: In this article by Las Vegas Sands Corp. et al., the authors report a lawsuit filed by Las Vegas Sands Corp. against unknown registrants of multiple domain names, including www.wn0000.com, www.wn... Check out the paper here 👇👇 doi.org/10.1089/glre.2016.201011
Title card for publication: LAS VEGAS SANDS CORP., a Nevada corporation, Plaintiff, v. UKNOWN REGISTRANTS OF www.wn0000.com, www.wn1111.com, www.wn2222.com, www.wn3333.com, www.wn4444.com, www.wn5555.com, www.wn6666.com, www.wn7777.com, www.wn8888.com, www.wn9999.com, www.112211.com, www.4456888.com, www.4489888.com, www.001148.com, and www.2289888.com, Defendants.
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Lead-DBS @lead-dbs.org · 21/08/2026
Classic publication using Lead-DBS: In this article by Mosley et al., the authors tested whether individual variability in initiation, inhibition and strategy use in Parkinson's patients receiving subthala... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Subthalamic deep brain stimulation identifies frontal networks supporting initiation, inhibition and strategy use in Parkinson's disease
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Lead-DBS @lead-dbs.org · 20/08/2026
Classic publication using Lead-DBS: In this article by Suresh et al., the authors tested nocturnal centromedian thalamic nucleus DBS in a patient with drug‑resistant idiopathic generalized epilepsy u... Check out the paper here 👇👇 www.frontiersin.org/articles/10.338…
Title card for publication: Case report: Nocturnal low-frequency stimulation of the centromedian thalamic nucleus improves sleep quality and seizure control
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Lead-DBS @lead-dbs.org · 19/08/2026
Classic publication using Lead-DBS: In this article by Davidson et al., the authors tested deep brain stimulation of the nucleus accumbens as a treatment for severe alcohol use disorder in a phase I pilot trial. Check out the paper here 👇👇 www.nature.com/articles/s41380-022-…
Title card for publication: Deep brain stimulation of the nucleus accumbens in the treatment of severe alcohol use disorder: a phase I pilot trial
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Lead-DBS @lead-dbs.org · 18/08/2026
Classic publication using Lead-DBS: In this article by Coblentz et al., the authors reported outcomes of GPi deep brain stimulation in 11 pediatric patients with refractory dystonia and used MR... Check out the paper here 👇👇 thejns.org/view/journals/j-neurosur…
Title card for publication: Mapping efficacious deep brain stimulation for pediatric dystonia
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Lead-DBS @lead-dbs.org · 17/08/2026
Classic publication using Lead-DBS: In this article by Wong et al., the authors report a case of GPi deep brain stimulation–induced ‘‘dystypia’’ (impaired typing), document improvement with the device... Check out the paper here 👇👇 www.frontiersin.org/articles/10.338…
Title card for publication: Case Report: Globus Pallidus Internus (GPi) Deep Brain Stimulation Induced Keyboard Typing Dysfunction
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Lead-DBS @lead-dbs.org · 16/08/2026
Classic publication using Lead-DBS: In this article by Bouwens Van Der Vlis et al., the authors report clinical outcomes in eight refractory OCD patients treated with ventral capsule/ventral striatum DBS a... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Ventral Capsule/Ventral Striatum Stimulation in Obsessive-Compulsive Disorder: Toward a Unified Connectomic Target for Deep Brain Stimulation?
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Lead-DBS @lead-dbs.org · 15/08/2026
New publication using Lead-DBS: In this article by Bryant et al., the authors introduce subcortex_visualization, an open-source Python and R toolbox providing standardized, vector-based 2D visualizations of region-level subco... Check out the paper here 👇👇 doi.org/10.64898/2026.01.23.699785
Title card for publication: Subcortex visualization: A toolbox for custom data visualization in the subcortex and cerebellum
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Lead-DBS @lead-dbs.org · 14/08/2026
New publication using Lead-DBS: In this article by Chen et al., they tested whether long‑latency reflex II (LLR II) is modulated by STN‑DBS parameters and dopaminergic medication in Parkinson's disease, finding higher LLR II with clin... Check out the paper here 👇👇 doi.org/10.1002/mds.70508
Title card for publication: Subthalamic Nucleus Deep Brain Stimulation Enhanced Long‐Latency Reflex
                    <scp>II</scp>
                    in Parkinson's Disease Through Rapid Subthalamic–Cortical Modulation
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Lead-DBS @lead-dbs.org · 13/08/2026
Classic publication using Lead-DBS: In this article by Filip et al., the authors tested whether subthalamic nucleus deep brain stimulation normalizes resting-state functional MRI metrics in Parkinson’s dis... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Mixed anxiety-depressive disorder in Parkinson’s disease associated with worse resting state functional response to deep brain stimulation of subthalamic nucleus
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Lead-DBS @lead-dbs.org · 12/08/2026
Classic publication using Lead-DBS: In this article by Hell et al., the authors recorded subthalamic nucleus LFPs in Parkinson’s patients during walking and rest with and without stimulation and showed gai... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Subthalamic oscillatory activity and connectivity during gait in Parkinson's disease
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Lead-DBS @lead-dbs.org · 11/08/2026
Classic publication using Lead-DBS: In this article by Dembek et al., the authors tested five published DBS sweetspot-mapping methods in silico across eight scenarios and found highly variable identified s... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Sweetspot Mapping in Deep Brain Stimulation: Strengths and Limitations of Current Approaches
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Lead-DBS @lead-dbs.org · 10/08/2026
Classic publication using Lead-DBS: In this article by Ge et al., the authors prospectively tested deep brain stimulation of the nucleus accumbens with or without the anterior limb of the internal capsule in 20 treatm... Check out the paper here 👇👇 www.nature.com/articles/s41398-025-…
Title card for publication: Effects of deep brain stimulation of the nucleus accumbens and anterior limb of the internal capsule on heroin addiction: Over five years of long-term follow-up in a prospective open-label pilot study
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Lead-DBS @lead-dbs.org · 09/08/2026
Classic publication using Lead-DBS: In this article by Zhang et al., the authors showed that electrode reconstruction can assist postoperative contact selection in deep brain stimulation. Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Electrode Reconstruction Assists Postoperative Contact Selection in Deep Brain Stimulation
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Lead-DBS @lead-dbs.org · 08/08/2026
New publication using Lead-DBS: In this article by Unknown et al., they announce a ScienceDirect article in press in Assessing Writing. Check out the paper here 👇👇 doi.org/10.1016/s1075-2935(04)00016…
Title card for publication: Announcement (ScienceDirect Article in Press)
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Lead-DBS @lead-dbs.org · 07/08/2026
New publication using Lead-DBS: In this article by Luo et al., the authors identified brain circuits associated with gait impairment after stroke and with gait changes following subthalamic DBS for Parkinson's disease, and found lesio... Check out the paper here 👇👇 doi.org/10.1002/ana.78320
Title card for publication: A Human Gait Circuit Derived from Brain Lesions and Deep Brain Stimulation
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Lead-DBS @lead-dbs.org · 05/08/2026
Classic publication using Lead-DBS: In this article by Segura-Amil et al., the authors used patient-specific probabilistic tractography in 20 Parkinson's disease patients with bilateral STN DBS to build models link... Check out the paper here 👇👇 onlinelibrary.wiley.com/doi/10.1002…
Title card for publication: Programming of subthalamic nucleus deep brain stimulation with hyperdirect pathway and corticospinal tract‐guided parameter suggestions
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Lead-DBS @lead-dbs.org · 04/08/2026
Classic publication using Lead-DBS: In this article by Ehlen et al., the authors tested effects of thalamic (VIM) deep brain stimulation in essential tremor patients on verbal fluency, finding DBS ON prolo... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Thalamic deep brain stimulation decelerates automatic lexical activation
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Lead-DBS @lead-dbs.org · 02/08/2026
Classic publication using Lead-DBS: In this article by Provenza et al., the authors used continuous ventral-striatum recordings from 12 people with treatment‑resistant OCD receiving DBS to show that pre‑stimulation th... Check out the paper here 👇👇 www.nature.com/articles/s41591-024-…
Title card for publication: Disruption of neural periodicity predicts clinical response after deep brain stimulation for obsessive-compulsive disorder
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Lead-DBS @lead-dbs.org · 30/07/2026
Classic publication using Lead-DBS: In this article by Zvarova et al., the authors developed and validated a multimodal neuroimaging‑informed model—combining active contact coordinates, electric fields, tract activations, and structur... Check out the paper here 👇👇 doi.org/10.1002/ana.78206
Title card for publication: Multimodal Image Guidance in Subthalamic Deep Brain Stimulation for Parkinson's Disease
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Lead-DBS @lead-dbs.org · 29/07/2026
New publication using Lead-DBS: In this review by Hagelschuer et al., the authors summarize current knowledge on deep brain stimulation in pediatric acquired dystonia, covering short- and long-term motor and non-motor effects... Check out the paper here 👇👇 doi.org/10.3389/fneur.2026.1735832
Title card for publication: Deep brain stimulation in children with acquired dystonia
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Lead-DBS @lead-dbs.org · 28/07/2026
Things are happening @netstim.org ..
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Lead-DBS @lead-dbs.org · 28/07/2026
Classic publication using Lead-DBS: In this article by Sarica et al., the authors tested MRI‑guided transcranial ultrasound stimulation (TUS) of M1, GPi, or occipital control in Parkinson’s patients with STN electrodes and... Check out the paper here 👇👇 doi.org/10.1126/scitranslmed.ady1883
Title card for publication: Transcranial ultrasound stimulation of motor networks in Parkinson’s disease informed by local field potential dynamics
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Lead-DBS @lead-dbs.org · 27/07/2026
Classic publication using Lead-DBS: In this article by Balachandar et al., the authors recorded GPi-DBS local field potentials in 10 children longitudinally and showed that status dystonicus is a distinct state charac... Check out the paper here 👇👇 www.nature.com/articles/s41467-025-…
Title card for publication: Status dystonicus is a distinct state characterized by pallidal beta-band activity
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Lead-DBS @lead-dbs.org · 26/07/2026
Classic publication using Lead-DBS: In this article by Leplus et al., the authors tested somatotopy of the sensory ventroposterior thalamus in six chronic neuropathic pain patients using directional deep brain sti... Check out the paper here 👇👇 onlinelibrary.wiley.com/doi/10.1002…
Title card for publication: Somatotopy of the sensory thalamus: inputs from directional deep brain stimulation in pain patients
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Lead-DBS @lead-dbs.org · 24/07/2026
New publication using Lead-DBS: In this article by Mazurek et al., the authors tested whether ICD‑10‑derived frailty (RAI) and age predicted outcomes after unilateral MRgFUS thalamotomy for essential tremor in 481 patients, finding ne... Check out the paper here 👇👇 doi.org/10.1002/mds.70435
Title card for publication: Frailty and Tremor Recurrence after Magnetic Resonance-Guided Focused Ultrasound (MRgFUS) Thalamotomy for Essential Tremor: An Age-Driven Association
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Lead-DBS @lead-dbs.org · 23/07/2026
Classic publication using Lead-DBS: In this article by Bush et al., the authors refined parameterization of the aperiodic 1/f component in LFP spectra and showed that cortical aperiodic exponen... Check out the paper here 👇👇 academic.oup.com/cercor/article/doi…
Title card for publication: Aperiodic components of local field potentials reflect inherent differences between cortical and subcortical activity
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Lead-DBS @lead-dbs.org · 22/07/2026
Classic publication using Lead-DBS: In this article by Martinez‐Nunez et al., the authors tested whether preoperative structural and functional connectivity predicts earlier symptom improvement af... Check out the paper here 👇👇 movementdisorders.onlinelibrary.wil…
Title card for publication: Functional Connectivity to the Cerebellum and Resting‐State Networks Predict Earlier Improvement of Dystonia Following Globus Pallidus Internus‐Deep Brain Stimulation ( <span style="font-variant:small-caps;">GPi‐DBS)</span>
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Lead-DBS @lead-dbs.org · 21/07/2026
New publication using Lead-DBS: In this article by D’Souza et al., the authors mapped sweet spots and connectivity associated with success versus failure of globus pallidus internus deep brain stimulation for antidyskinetic... Check out the paper here 👇👇 doi.org/10.1016/j.neurom.2026.06.462
Title card for publication: Success and Failure With the Antidyskinetic Effect of Globus Pallidus Internus Deep Brain Stimulation: A Sweet Spot and Connectivity Analysis in the CSP-468 Cohort
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Lead-DBS @lead-dbs.org · 20/07/2026
Classic publication using Lead-DBS: In this article by DiRisio et al., the authors mapped patient-specific structural connectivity from simulated DBS... Check out the paper here 👇👇 thejns.org/view/journals/j-neurosur…
Title card for publication: White matter connectivity of subthalamic nucleus and globus pallidus interna targets for deep brain stimulation
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Lead-DBS @lead-dbs.org · 19/07/2026
Classic publication using Lead-DBS: In this article by Saluja et al., the authors used diffusion MRI tractography to map the DRTT and CTT in a case where DBS rescued recurrent essential tremor after an... Check out the paper here 👇👇 www.frontiersin.org/article/10.3389…
Title card for publication: Case Report on Deep Brain Stimulation Rescue After Suboptimal MR-Guided Focused Ultrasound Thalamotomy for Essential Tremor: A Tractography-Based Investigation
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Lead-DBS @lead-dbs.org · 18/07/2026
Classic publication using Lead-DBS: In this article by Madan et al., the authors introduce Lead-Tutor, an open-access educational resource pairing an anonymized imaging dataset of ten DBS cases (pre/post-op MRI and CT) with a Lead-... Check out the paper here 👇👇 doi.org/10.52294/001c.129658
Title card for publication: Lead-Tutor: An open-access educational resource for deep brain stimulation electrode localizations
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Lead-DBS @lead-dbs.org · 17/07/2026
Classic publication using Lead-DBS: In this article by Dembek et al., the authors investigated how prevalent deviations from the intended implantation orientation are for directional deep brain stimulation... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Directional DBS leads show large deviations from their intended implantation orientation
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Lead-DBS @lead-dbs.org · 16/07/2026
Classic publication using Lead-DBS: In this article by Lévy et al., the authors mapped structure–function relationships in the posterior subthalamic area using directional deep brain stimulation to better... Check out the paper here 👇👇 linkinghub.elsevier.com/retrieve/pi…
Title card for publication: Structure-function relationship of the posterior subthalamic area with directional deep brain stimulation for essential tremor
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Lead-DBS @lead-dbs.org · 15/07/2026
Classic publication using Lead-DBS: In this article by Calvano et al., the authors report a case of secondary myoclonus‑dystonia after childhood ADEM that was alleviated by unilateral GPi DBS and use... Check out the paper here 👇👇 www.frontiersin.org/articles/10.338…
Title card for publication: Case report: Unilateral GPi DBS in secondary myoclonus-dystonia syndrome after acute disseminated encephalomyelitis
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Lead-DBS @lead-dbs.org · 14/07/2026
Classic publication using Lead-DBS: In this article by Herrojo Ruiz et al., the authors tested whether timing deviations in skilled memorized piano performance exhibit long-range temporal correla... Check out the paper here 👇👇 journal.frontiersin.org/article/10.…
Title card for publication: Long-range correlation properties in timing of skilled piano performance: the influence of auditory feedback and deep brain stimulation
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Lead-DBS @lead-dbs.org · 13/07/2026
Classic publication using Lead-DBS: In this article by Dai et al., the authors report on clinical outcomes and functional connectivity associated with subthalamic deep brain stimulation for refractory Gilles de la T... Check out the paper here 👇👇 link.springer.com/10.1007/s00415-02…
Title card for publication: Correction: Subthalamic deep brain stimulation for refractory Gilles de la Tourette’s syndrome: clinical outcome and functional connectivity
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Lead-DBS @lead-dbs.org · 12/07/2026
Classic publication using Lead-DBS: In this article by Liu et al., the authors present a case of a 49-year-old woman with Parkinson’s disease who developed severe urinary incontinence after 27 months... Check out the paper here 👇👇 thejns.org/view/journals/j-neurosur…
Title card for publication: Urinary incontinence following deep brain stimulation of the globus pallidus internus: case report
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Lead-DBS @lead-dbs.org · 11/07/2026
Classic publication using Lead-DBS: In this article by Sugiyama et al., the authors discuss the concept of using a single deep brain stimulation lead to stimulate both the thalamus and subthalamus as... Check out the paper here 👇👇 www.frontiersin.org/articles/10.338…
Title card for publication: A Single DBS-Lead to Stimulate the Thalamus and Subthalamus: Two-Story Targets for Tremor Disorders
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Lead-DBS @lead-dbs.org · 10/07/2026
New publication using Lead-DBS: In this article by Agashe et al., the authors tested whether thalamic local field potential spectral profiles can physiologically confirm centromedian–parafascicular targeting during DBS for dr... Check out the paper here 👇👇 doi.org/10.3389/fnins.2026.1855048
Title card for publication: Local field potentials for target localization in centromedian deep brain stimulation for epilepsy
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Lead-DBS @lead-dbs.org · 09/07/2026
New publication using Lead-DBS: In this article by Barlatey et al., the authors tested the robustness of DBS lead reconstruction using two distinct postoperative CT scans per patient and found mean lead tip translation of 0.79 mm, ind... Check out the paper here 👇👇 doi.org/10.1159/000552349
Title card for publication: Robustness of Lead Reconstruction for Deep Brain Stimulation Modeling and Probabilistic Mapping
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