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Luc Blassel

@lblassel.bsky.social
62 followers 480 following 17 posts

Computational Biologist - deep learning for phylogenetics

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Reposted by Luc Blassel
Laurent Jacob @laurentjacob.bsky.social · 03/06/2026
The video recordings of the legend 2025 conference held last December on machine learning for evolutionary genomics are now online ! Feel free to have a look if you missed the conference. www.canal-u.tv/chaines/lisn...
The legend 2025 conference logo showing a legendary being holding a tree in the palm of their hand, with snowy mountains in the background.
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Luc Blassel @lblassel.bsky.social · 16/10/2025
We’re very excited to finally share our latest work: Phyloformer 2, a deep end-to-end phylogenetic reconstruction method: arxiv.org/abs/2510.12976 Using neural posterior estimation, it outperforms Phyloformer 1 and maximum-likelihood methods under simple and complex evolutionary models. 🧵1/17
A three panel figure describing the Phyloformer 2 (PF2) method. The top panel describes the architecture of the PF2 neural network. The bottom right panel describes how PF2 estimates the posterior probability of a tree given a sequence emebdding at train time. The bottom left panel describes how PF2 samples trees from the learned posterior at inference time.
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Reposted by Luc Blassel
Roland Faure @rfaure.bsky.social · 03/10/2025
Our preprint on our new metagenomic HiFi assembler Alice is out 🥳 Based on a *new sketching method* (🧵1/6) 👉 Preprint www.biorxiv.org/content/10.1... 👉 Github github.com/rolandfaure/...
biorxiv.org
Alice: fast and haplotype-aware assembly of high-fidelity reads based on MSR sketching
We introduce Mapping-friendly Sequence Reduction (MSR) sketches, a sketching method for high-fidelity (HiFi) long reads, and Alice, an assembler that operates directly on these sketches. MSR produces ...
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Reposted by Luc Blassel
mariemorel.bsky.social @mariemorel.bsky.social · 28/05/2025
La vidéo sur notre projet de recherche est en ligne ! Merci encore à toute l'équipe d'animal pensant pour leur incroyable travail ! D’où viennent les fleurs ? lejournal.cnrs.fr/videos/dou-v...
lejournal.cnrs.fr
D’où viennent les fleurs ?
Les fleurs dominent le monde végétal, mais leur origine reste un mystère. Dans cette vidéo en partenariat avec Le Monde, des chercheurs du CNRS tentent de remonter à l’ancêtre commun de toutes les pla...
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Reposted by Luc Blassel
Laurent Jacob @laurentjacob.bsky.social · 24/06/2024
All this work was done by Luca Nesterenko and @lblassel.bsky.social , assisted by P. Veber, Bastien Boussau and myself. The code and data are available at github.com/lucanest/Phy... Please share if you find this interesting, and we welcome your feedback :)
A sketch summarizing the entire Phyloformer process.
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Reposted by Luc Blassel
Laurent Jacob @laurentjacob.bsky.social · 24/06/2024
We just released a preprint for Phyloformer, a likelihood-free inference method for phylogenetic reconstruction: biorxiv.org/content/10.1... Faster than distance methods like neighbor joining, it outperforms maximum likelihood methods under complex models of sequence evolution. 🧵
A logo symbolizing the Phyloformer process: it starts from an artificial neural networks and ends with a phylogeny.
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