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Laura Chacon Machado

@laurachaconmachado.bsky.social
37 followers 43 following 10 posts

PhD candidate at Joe Peters Lab, Cornell Microbiology. Interested in mobile genetic elements, particularly Tn7-like transposons.

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Reposted by Laura Chacon Machado
Cedric Feschotte @cedricfeschotte.bsky.social · 24/02/2025
Feels awkward but necessary to celebrate scientific progress in this imperiled time for US biomedical research. Proud of our latest paper out today exploring the role of transposable elements in antiviral resistance to HIV 🦠 genomebiology.biomedcentral.com/articles/10.... 🧵1/n
genomebiology.biomedcentral.com
Transposable elements may enhance antiviral resistance in HIV-1 elite controllers - Genome Biology
Background Less than 0.5% of people living with HIV-1 are elite controllers (ECs)—individuals who maintain undetectable plasma viremia without antiretroviral therapy, despite having replication-compet...
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Laura Chacon Machado @laurachaconmachado.bsky.social · 18/02/2025
Our preprint describing a family of Tn7-like transposons that evolved to target CRISPR repeats is now published at Mobile DNA #Tn7 #transposons #mobileDNA 1/10 mobilednajournal.biomedcentral.com/articles/10....
mobilednajournal.biomedcentral.com
A family of Tn7-like transposons evolved to target CRISPR repeats - Mobile DNA
Tn7 family transposons are mobile genetic elements known for precise target site selection, with some co-opting CRISPR-Cas systems for RNA-guided transposition. We identified a novel group of Tn7-like...
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