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Lucas Arnoldt

@larnoldt.bsky.social
94 followers 411 following 7 posts

PhD student @ Helmholtz Munich | Interested in Genetics, Omics, Digital Health, Deep Learning.

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Reposted by Lucas Arnoldt
Julius Upmeier zu Belzen @juliusuzb.bsky.social · 05/08/2026
🧬 New preprint! An interpretable omnigenic neural network architecture for the human genome We introduce the Omnigenic Model (OGM), a neural network architecture for human genetics. It uses biological system structure to aggregate genetic variation for disease risk prediction.
doi.org
1155
Lucas Arnoldt @larnoldt.bsky.social · 16/06/2025
Current multimodal single-cell integration methods act as black boxes, lacking meaningful interpretability. We introduce NetworkVI, a VAE that performs integration via gene-gene interactions and the Gene Ontology for biologically grounded analysis. www.biorxiv.org/content/10.1...
biorxiv.org
110