Very excited to introduce mismatch-assisted toehold exchange (MATE) concept for the first time, our new magnetic diagnostics cascades:
biorxiv.org/content/10.1...
Excellent work by Rebecca, "Metrology4life" 2nd PhD student and Great collaboration with @petrsulc.bsky.social
biorxiv.org
Mismatch-Assisted Toehold Exchange Cascades for Magnetic Nanoparticle-Based Nucleic Acid Diagnostics
Sensitive, simple, and rapid detection of nucleic acid sequences at point-of-care (POC) settings is still an unmet quest. Magnetic readout assays combined with toehold-mediated strand displacement (TM...