Lauric Ferrat @laferrat.bsky.social · 11/02/2026Many people to thanks for this international and interdisciplinary work Gonçalo Leiria, Brett McQueen, Jonathan Fieldsend, Richard Oram, Marian Rewers, Bill Hagopian, Conner Jackson and Breakthrough T1D 010
Lauric Ferrat @laferrat.bsky.social · 11/02/2026The top strategy—autoantibody testing in high-genetic-risk groups—achieves an ICER of $28k per life year gained. More details in the article. 100
Lauric Ferrat @laferrat.bsky.social · 11/02/2026Our new microsimulation model to optimise T1D screening by balancing cost, pragmatism, and reduced diabetic ketoacidosis is out. #T1D #T1Dscreening doi.org/10.1007/s402...doi.orgDevelopment of a Patient-Level Multi-objective Optimisation Model for Screening Strategies for Childhood Type 1 Diabetes - PharmacoEconomicsObjective To develop a patient-level simulation model of type 1 diabetes (T1D) covering both childhood and adulthood. The goal is to identify and evaluate the cost-effectiveness of optimal screening f... 121
Reposted by Lauric FerratHarry Wright @hiwwright.bsky.social · 06/02/2026Excited to share my first preprint on federated conditional analysis of rare single variant and aggregate association tests across six genetically-inferred ancestry groups in All of Us and UK Biobank doi.org/10.64898/202... 12211
Reposted by Lauric FerratDiabetologia @diabetologiajnl.bsky.social · 23/05/2025Addressing type 1 diabetes prediction challenges: study compares trade-offs between cost, performance models and participant time and provides insights for tailored risk screening. #T1D #DiabetesResearch #RiskScreening link.springer.com/article/10.1... 🔓link.springer.comType 1 diabetes prediction in autoantibody-positive individuals: performance, time and money matter - DiabetologiaAims/hypothesis Efficient prediction of clinical type 1 diabetes is important for risk stratification and monitoring of autoantibody-positive individuals. In this study, we compared type 1 diabetes pr... 061
Reposted by Lauric Ferraterinltempleman.bsky.social @erinltempleman.bsky.social · 23/07/2025🚨Big news! Excited to share my first PhD paper!🎉 We validated & improved a T1D risk model using TrialNet data (originally from TEDDY), boosting accuracy 📈 bmcmedicine.biomedcentral.com/articles/10.... Try the web tool 👉 t1dpredictor.diabetesgenes.org #T1D #RiskPrediction #PrecisionMedicine #TrialNetbmcmedicine.biomedcentral.comDevelopment and recalibration of a multivariable type 1 diabetes prediction model for type 1 diabetes across multiple screening studies - BMC MedicineBackground Accurate type 1 diabetes prediction is important to facilitate screening for pre-clinical type 1 diabetes to enable potential early disease-modifying interventions and to reduce the risk of... 0115
