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labtinnefeld.bsky.social

@labtinnefeld.bsky.social
43 followers 36 following 15 posts

Tinnefeld lab @lmumuenchen.bsky.social 🧬

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labtinnefeld.bsky.social @labtinnefeld.bsky.social · 28/07/2026
GETvNA combines graphene energy transfer with vertically arranged DNA, enabling precise observation of biomolecular movements. The platform opens new possibilities for dynamic structural biology and for investigating molecular processes in real time. www.nature.com/articles/s41...
nature.com
Single-molecule dynamic structural biology with vertically arranged DNA on a fluorescence microscope - Nature Methods
Graphene energy transfer with vertical nucleic acids (GETvNA) is a general approach enabling dynamical observations of DNA structural changes and DNA–protein interactions with spatial resolution down ...
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labtinnefeld.bsky.social @labtinnefeld.bsky.social · 28/07/2026
Congratulations to Lars for getting first place in the CeNS Nano Innovation Award 2026 for co-developing GETvNA. Image credit: @cens-lmu.bsky.social Also, check out the full LMU press release here: www.lmu.de/en/newsroom/....
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labtinnefeld.bsky.social @labtinnefeld.bsky.social · 06/07/2026
Philip presented our recent work on DNA computing 🖥️ and biosensing at #BayOConnect 2026 in Munich. His talk highlighted how #DNAnanotechnology 🧬 🔬 enables programmable molecular systems for computation and highly sensitive biosensing. @philiptinnefeld.bsky.social
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labtinnefeld.bsky.social @labtinnefeld.bsky.social · 28/10/2025
5/5 Congratulations to the authors🥳 Martina Pfeiffer, Fiona Cole, Dongfang Wang, YonggangKe and @philiptinnefeld.bsky.social
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labtinnefeld.bsky.social @labtinnefeld.bsky.social · 28/10/2025
4/5 How? SEPP is a spring-loaded network of DNA “antijunctions” that flip between states, like tiny molecular switches. We can program them with DNA strands to make logic gates, timed actions, and even cargo release. Basically, tiny robots doing science at 1 billionth the size🤏
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labtinnefeld.bsky.social @labtinnefeld.bsky.social · 28/10/2025
3/5 Applications? From smart nanosensors to molecular factories and future therapeutics. We’re one step closer to computers made of DNA — literally. 🧠🧬
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labtinnefeld.bsky.social @labtinnefeld.bsky.social · 28/10/2025
2/5 Think “field-programmable gate array,” but at the nanometer scale — powered by fuel strands instead of electricity. Meet SEPP: the Serial Execution of Programmable Processes platform for modular, logic-gated nanorobots 🤖
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labtinnefeld.bsky.social @labtinnefeld.bsky.social · 28/10/2025
1/5🚀🔬 New paper alert! We built a spring-loaded DNA origami nanorobot that can sense, compute, and act — basically, a molecular PC made of DNA 🧬💻 #DNAorigami #nanotech #robotics #moleculardesign #SciRobotics www.science.org/doi/10.1126/...
science.org
Spring-loaded DNA origami arrays as energy-supplied hardware for modular nanorobots
Spring-loaded DNA origami arrays enable nanorobots to integrate diverse inputs with logic-based, sequential operations.
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Reposted by @labtinnefeld.bsky.social
Samrat Basak @samratb.bsky.social · 12/08/2025
Excited to share — our project from @labtinnefeld.bsky.social with Heinrich Grabmayr from @jungmannlab.bsky.social has been selected for the CeNS Investment Fund from @cens-lmu.bsky.social ! www.cens.lmu.de/en/research/...
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labtinnefeld.bsky.social @labtinnefeld.bsky.social · 25/08/2025
4/4 Huge shout-out to the amazing team🥳: TimSchroeder, Julian Bauer, Patrick Schüler, Jonas Zähringer, Fiona Cole, Giovanni Ferrari, Laura Barnard, Karen Gronbach, Gereon Andreas Brüggenthies, @philiptinnefeld.bsky.social
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labtinnefeld.bsky.social @labtinnefeld.bsky.social · 25/08/2025
3/4 MPUs are fully modular🖥️. We built: ✔ All basic Boolean logic gates ✔ Multi-input compact gates ✔ A half adder ✔ Even non-Boolean logic
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labtinnefeld.bsky.social @labtinnefeld.bsky.social · 25/08/2025
2/4 🧬💡Molecular Processing Units (MPUs) are integrated on DNA origamis. They switch from transient (0) to stable (1) DNA states via input strand addition. ✨See GIF🔝
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labtinnefeld.bsky.social @labtinnefeld.bsky.social · 25/08/2025
1/4 📢🥳now online: BROWNIAN DNA COMPUTING - Unlike fuel-driven molecular computing with high-energy barriers, it exploits thermal fluctuations. Inputs rectify state access, enabling fast, low-energy computation. 📜More in our preprint: biorxiv.org/content/10.1...
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labtinnefeld.bsky.social @labtinnefeld.bsky.social · 28/07/2025
3/3 Congratulations to all the authors for the team work🥳: @renukkayaadav.bsky.social, Kateryna , Mihir, Vivien, Benedikt, Jan, Cindy, Michi, Giovanni, Leonie, Sophia, @glembockyte.bsky.social, Tim Liedl and @philiptinnefeld.bsky.social
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labtinnefeld.bsky.social @labtinnefeld.bsky.social · 28/07/2025
2/3 We made a short video📽️that provides a quick summary of the topic.
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labtinnefeld.bsky.social @labtinnefeld.bsky.social · 28/07/2025
1/3 🚨🥳New paper out in Advanced Materials! We bring attomolar, amplification-free DNA detection to the point-of-care using DNA origami nanoantennas.🧬Check it out here: advanced.onlinelibrary.wiley.com/doi/10.1002/...
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