iiinova — where your digital self keeps evolving

Helen Rowe @RoweLab @labrowe.bsky.social · 28/09/2026

Fortuitous rendezvous lunch with some previous and current lab members, like a ray of light on a Friday afternoon! The best part of academia is the people you meet 😊

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Helen Rowe @RoweLab @labrowe.bsky.social · 14/08/2026

* Hot off the press from the Rowe Lab 📢 * : For in depth insight on LINE-1 jumping genes, from their regulation to their multifaceted roles in cancer immunity, read Holly Jefferson's review here: www.mdpi.com/1999-4915/18...

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Helen Rowe @RoweLab @labrowe.bsky.social · 16/06/2026

‪doi: doi.org/10.1038/s414... 📣 Our study is now out in Nature Communications detailing that the type I interferon pathway is suppressed by HUSH in early human development: Its complete epigenetic lockdown!! Incredible work from James Holt 📣 😎

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Helen Rowe @RoweLab @labrowe.bsky.social · 29/10/2025

How do pluripotent stem cells resist harmful interferon responses to safeguard development? Through total epigenetic lockdown of ligands, sensors and effectors of IFN-I. In our preprint, James Holt shares his PhD discoveries on the ground state of immune evasion 😊: www.biorxiv.org/cgi/content/...

biorxiv.org

Epigenetic lockdown of type I interferon sensing and signalling in human pluripotent cells.

The Human Silencing Hub (HUSH) complex safeguards genome integrity in human somatic cells by repressing transposable elements and regulating type I interferon (IFN-I) induction. In early development, ...

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Reposted by Helen Rowe @RoweLab

Rebecca Berrens @rberrens.bsky.social · 19/11/2024

Please register for the course on Transposable elements in #genomics and #datascience. We will be sharing the magic of #nanopore long reads for #transposon expression #tesky

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Helen Rowe @RoweLab @labrowe.bsky.social · 29/08/2024

I’m happy to announce that I’ve been promoted to Professor! 🥳 I’m so grateful to everyone who has supported me, to my amazing lab members and to all who have made my scientific journey fun along the way ☀️. Thank you Queen Mary University!

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Helen Rowe @RoweLab @labrowe.bsky.social · 19/06/2024

I am thrilled and incredibly proud that recent PhD student @Liane Fernandes from my lab @QMUL has won a prestigious EMBO Fellowship! Exciting science ahead ❤️ 🏆

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Helen Rowe @RoweLab @labrowe.bsky.social · 18/03/2024

How do tumours evade destruction by the immune system? We are recruiting two postdocs (wet lab/dry lab) to shed light on epigenetic checkpoints of anti-tumour immunity in lung cancers, funded by CRUK. Please get in touch to find out more! www.qmul.ac.uk/jobs/vacanci... www.qmul.ac.uk/jobs/vacanci...

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Helen Rowe @RoweLab @labrowe.bsky.social · 02/02/2024

I am honoured to receive a Programme Foundation Award from Cancer Research UK on epigenetic regulation of immune evasion in non-small cell lung cancer. Thanks to my co-investigators, collaborators, mentors, lab & @qmulepigenetics.bsky.social for supporting this exciting translational project.

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Reposted by Helen Rowe @RoweLab

QMUL Centre for Epigenetics @qmulepigenetics.bsky.social · 11/01/2024

Please join us for the @QMULepigenetics seminar by Kristian Helin from @icr_london 11th Jan. 15.30GMT. venue: Derek Willoughby Lecture Theatre, at our Charterhouse Square campus. or online link at qmulepigenetics.com/webinars

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Reposted by Helen Rowe @RoweLab

Rita Rebollo @ritarebollo.bsky.social · 18/12/2023

Dear TE family, it is time! The early-bird registration ends January 15th already! Abstract for talks ends February 15th! Start procrastinating by doing something useful: register to #icte2024 ! See you soon! #transposon

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Helen Rowe @RoweLab @labrowe.bsky.social · 03/01/2024

Enlightening review from @KathleenHBurns lab: genesdev.cshlp.org/content/37/2...: LINE-1 activity and jumping contributes to genetic instability in cancer and understanding LINE-1 deregulation could lead to new therapeutic opportunities. A must-read.

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Helen Rowe @RoweLab @labrowe.bsky.social · 30/12/2023

Elegant preprint identifying mutually exclusive targeting of HUSH1 vs. HUSH2 chromatin complexes for silencing dangerous LINE-1 elements in the human genome: www.biorxiv.org/content/10.1...

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