Yuval Nir @labnir.bsky.social · 09/09/2026A big shout-out to two excellent postdocs on my team, Barak Hadad and Flavio Schmidig who recently published exciting papers and received prestigious awards. Very proud to see them taking these next steps! 100
Yuval Nir @labnir.bsky.social · 04/06/2026Congratulations @falach.bsky.social for Michaelson's Excellence Award in Alzheimer's Disease Research! very proud of you & your achievements in developing novel methods for detecting abnormal sleep activities in Alzheimer's. Publication soon stay tuned 🤩 100
Yuval Nir @labnir.bsky.social · 30/11/2025The Mind's Eye: A quest from vision to consciousness - Symposium in honor of Rafi Malach Incredible lineup assembled celebrating the career of an amazing scientist Join us on December 14-15 at the Weizmann Institute ! 130
Yuval Nir @labnir.bsky.social · 09/10/2025Proud and delighted to deliver the keynote presentation at “Sleep Down Under 2025” Adelaide, organized by the Australasian Sleep Association #SleepDownUnder 010
Yuval Nir @labnir.bsky.social · 10/09/2025(6/6) ✨ Take-home: LC neurons are not a single unitary arousal system. LC→PRN brainstem pathway is critical for sound-evoked awakening Thanks to team 🙌 led by amazing @nmatosevich.bsky.social , Noa Regev, U. Kimchi, N. Zelinger, @SinaKabaha Amit Marmelstein @noamgabay.bsky.social 120
Yuval Nir @labnir.bsky.social · 10/09/2025(5/6) What happens if you silence LC synapses? Using an optoGPCR (PdCO), we found that shutting down LC→PRN boosts sigma power and deepens NREM sleep. Silencing both PRN + BF was even more effective. 120
Yuval Nir @labnir.bsky.social · 10/09/2025(4/6) Timing is everything ⏱️ Optogenetic activation showed that sound-evoked awakening depends on which LC neurons are active AND when they fire - synchrony with the sound is key. 110
Yuval Nir @labnir.bsky.social · 10/09/2025(3/6) Here’s the twist: only the LC→PRN pathway shows a fast NE surge when sounds are played during sleep. That rapid signal predicts whether the sound will wake the mouse. 110
Yuval Nir @labnir.bsky.social · 10/09/2025(2/6) Not all LC pathways are the same 👀 We compared LC projections to the basal forebrain (BF) and to the brainstem pontine reticular nucleus (PRN). They turned out to be partially distinct populations. 120
Yuval Nir @labnir.bsky.social · 05/06/2025Had a brilliant time at #SXSWLondon Corundum Neuroscience panel discussing the future of sleep - issues ranging from monitoring health, through unique interventions, recording EEG via earbuds, to disengaging from ruminations falling asleep & lucid dreaming w/ Caroline Lustenberger, Simon Bachmann 010
Yuval Nir @labnir.bsky.social · 21/05/2025So very proud of our own @OmerBenBarak1 who received the prestigious Sieratzki PhD scholarship for her research on pupillometry and gaze imaging in closed eye conditions, well done Omer! 000
Yuval Nir @labnir.bsky.social · 10/04/2025Celebrating spring holidays with lab yoga and picnic, thanks Revital Hershkovich for great lesson! Happy Passover 010
Yuval Nir @labnir.bsky.social · 03/04/2025Fantastic #inTRACE conference in Parma, bridging neuroscience and clinic in intracranial recordings & stimulation, non-invasive measures, sleep, modeling. Attending with clinical partners Ido Strauss and Firas Fahoum, huge thx to organizers Andrea Pigorini Pietro Avanzini Nigruada hospital team 000
Yuval Nir @labnir.bsky.social · 25/01/2025On my way to GRC Consciousness, Anesthesia & Evolutionary Biology, what a lineup! exciting 010
Yuval Nir @labnir.bsky.social · 14/01/2025Had such a great time at Israeli Society for Neuroscience meeting #ISFN Great science w/ a session on #sleep - of course - so many posters from lab 💪 Noa Matosevich winning best poster award 🤩and above all - simply great to hang out with my incredible team I am blessed 🙏 010
