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Laboratory Investigation

@labinvest.bsky.social
4 followers 4 following 12 posts

Official Journal of the United States and Canadian Academy of Pathology. LI offers prompt publication of high-quality original research that advances the understanding and classification of human disease. www.laboratoryinvestigation.com

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Laboratory Investigation @labinvest.bsky.social · 24/09/2026
New from Laboratory Investigation 🔬 | Integrating molecular, histopathologic, and spatial transcriptomic profiling reveals shared pathogenic features of lymphatic malformations and highlights NFATC1 activation in lymphatic endothelial cells. 🔗 Hirose et al. Read the article buff.ly/NgRf8ra
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Laboratory Investigation @labinvest.bsky.social · 22/09/2026
New from Laboratory Investigation 🔬 | Optimizing DNA extraction from archival prostate biopsies to maximize DNA yield from limited tumor samples for molecular testing. 🔗 Amaral et al. Read the article: www.laboratoryinvestigation.org/article/S002...
laboratoryinvestigation.org
Optimizing DNA Extraction from Archival Prostate Biopsy Samples
In this paper, we compare the performance of three distinct nucleic acid extraction protocols in a large population-based prostate cancer cohort, aiming to optimize DNA yield from limited tumor…
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Laboratory Investigation @labinvest.bsky.social · 18/09/2026
New from Laboratory Investigation 🔬 | Identifying two novel compound heterozygous ADAMTS17 variants associated with Weill–Marchesani syndrome 4, including a deep intronic variant shown to disrupt normal splicing. 🔗 Ku et al. Read the article: www.laboratoryinvestigation.org/article/S002...
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Laboratory Investigation @labinvest.bsky.social · 26/08/2026
New from Laboratory Investigation 🔬 | Renal Pathology Society Survey of Global Renal Pathology Practice Variation in Pre-analytic and Analytic Phases @Renalpathsoc 🔗 Gaut et al. Read the article: www.laboratoryinvestigation.org/article/S002...
laboratoryinvestigation.org
Renal Pathology Society Survey of Global Renal Pathology Practice Variation in Pre-analytic and Analytic Phases
This study aims to examine current global renal biopsy pre-analytic and analytic variability according to country income status. Technology access, pathologist workforce, and case volume variations…
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Laboratory Investigation @labinvest.bsky.social · 26/08/2026
New from Laboratory Investigation 🔬 | Spatial Transcriptomics of Micropapillary, Plasmacytoid, and Sarcomatoid Urothelial Carcinoma Reveals Distinct Molecular Landscapes @TingZhaoPathdoc 🔗 Zhao et al. Read the article: www.laboratoryinvestigation.org/article/S002...
laboratoryinvestigation.org
Spatial Transcriptomics of Micropapillary, Plasmacytoid, and Sarcomatoid Urothelial Carcinoma Reveals Distinct Molecular Landscapes
Consensus molecular classes of urothelial carcinoma (UC) include basal/squamous (Ba/Sq), luminal papillary (LumP), luminal nonspecified (LumNS), luminal unstable (LumU), stroma-rich, and…
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Laboratory Investigation @labinvest.bsky.social · 26/08/2026
New from Laboratory Investigation 🔬 | Prediction of Lymph Node Metastasis in Early Gastric Cancer Using Foundation Model Ensembles and Patch-Based Histopathological Interpretation 🔗 Chung et al. Read the article: www.laboratoryinvestigation.org/article/S002...
laboratoryinvestigation.org
Prediction of Lymph Node Metastasis in Early Gastric Cancer Using Foundation Model Ensembles and Patch-Based Histopathological Interpretation
Accurate prediction of lymph node metastasis (LNM) remains challenging in early gastric cancer (EGC), particularly when determining the need for additional surgery after endoscopic resection. We…
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Laboratory Investigation @labinvest.bsky.social · 26/08/2026
New from Laboratory Investigation 🔬 | Renal Pathology Society Survey of Global Renal Pathology Practice Variation in Pre-analytic and Analytic Phases @Renalpathsoc 🔗 Gaut et al. Read the article: www.sciencedirect.com/science/arti...
sciencedirect.com
https://www.sciencedirect.com/science/article/pii/S0023683726000899
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Laboratory Investigation @labinvest.bsky.social · 26/08/2026
New from Laboratory Investigation 🔬 | Spatial Transcriptomics of Micropapillary, Plasmacytoid, and Sarcomatoid Urothelial Carcinoma Reveals Distinct Molecular Landscapes @TingZhaoPathdoc 🔗 Zhao et al. Read the article: www.sciencedirect.com/science/arti...
sciencedirect.com
https://www.sciencedirect.com/science/article/pii/S0023683726000905
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Laboratory Investigation @labinvest.bsky.social · 26/08/2026
New from Laboratory Investigation 🔬 | Prediction of Lymph Node Metastasis in Early Gastric Cancer Using Foundation Model Ensembles and Patch-Based Histopathological Interpretation 🔗 Chung et al. Read the article: www.sciencedirect.com/science/arti...
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Laboratory Investigation @labinvest.bsky.social · 13/08/2026
New from Laboratory Investigation 🔬 | Intratumoral macrophage subsets and CD8 are associated with favorable outcomes during PD-1–based immunotherapy #openaccess 🔗 Ohkuma et al. Read the article: www.laboratoryinvestigation.org/article/S002...
laboratoryinvestigation.org
Association of Intratumoral Macrophage Subsets with Treatment Outcomes in Patients with Stage IV Solid Tumors
To assess whether pretreatment intratumoral macrophage-associated and T-cell marker-positive areas are associated with treatment outcomes in patients with stage IV solid tumors receiving programmed…
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Laboratory Investigation @labinvest.bsky.social · 24/03/2025
THE #USCAP2025 EXHIBIT HALL IS OPEN! Make sure to stop by the USCAP booth in the center of the Exhibit Hall to say hi to your FAVORITE #ModernPathology and #LaboratoryInvestigation JOURNAL MANAGERS! #Pathology
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Laboratory Investigation @labinvest.bsky.social · 23/03/2025
Laboratory Investigation is an international journal owned by the United States and Canadian Academy of #Pathology. Laboratory Investigation offers prompt publication of high-quality original research that advances the understanding and classification of #humandisease. WE ARE AT #USCAP2025!
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