iiinova — where your digital self keeps evolving

Reposted by KruegerLab

Adrian Liston @labliston.bsky.social · 30/01/2026

Our new book "Self-Doubt" is written by scientists for scientists. You might think you are alone when you doubt your ability or suitability for science - you aren't. We all question ourselves and carry doubt with us daily. www.amazon.co.uk/Self-Doubt-A...

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KruegerLab @kruegerlab.bsky.social · 22/12/2025

We are hiring! A fully-funded postdoc position in the field of T-cell biology is available immediately at our lab at JLU. Please check out the full ad here: www.uni-giessen.de/de/ueber-uns... or contact me for more details.

uni-giessen.de

Postdoc (m/f/d) in the field of T-Cell Biology

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KruegerLab @kruegerlab.bsky.social · 01/10/2025

Congrats James! Well deserved!

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Reposted by KruegerLab

Adrian Liston @labliston.bsky.social · 19/09/2025

For our #flowcytometry peeps, would you like to have a single fix/perm protocol that is optimised for everything? One that preserves fluorophores while allowing simultaneous TF and cytokine staining? How about 100-fold cheaper? You got it: currentprotocols.onlinelibrary.wiley.com/doi/10.1002/...

currentprotocols.onlinelibrary.wiley.com

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Reposted by KruegerLab

European Journal of Immunology @eurjimmunol.bsky.social · 22/08/2025

Awesome performance of the band composed of great immunologists, including our Editor-in-Chief Matteo Iannacone behind the keyboard, at the #IUIS2025 Congress Party! 🎹🎸🎶

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Reposted by KruegerLab

European Journal of Immunology @eurjimmunol.bsky.social · 21/08/2025

Steffen Jung announced Andreas Radbruch as keynote speaker at #IUIS2025, highlighting his strong support for European Immunology and the importance of backing EJI and European research! Andreas presenting his newest EJI article by Schneider-Revueltas et al. onlinelibrary.wiley.com/doi/10.1002/...

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Reposted by KruegerLab

RTG 2355 @rtg2355.bsky.social · 01/07/2025

Back from another great retreat to Schmitten, Taunus - this year with guests from @4r-rtg.bsky.social and from @jlugiessen.bsky.social and @mpi-hlr.bsky.social core facilities. We had inspiring method sessions on scientific diagrams & statistics, complexome proteomics, microscopy & image analysis ..

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KruegerLab @kruegerlab.bsky.social · 17/06/2025

Congrats! I really hope that this approach to science will set an example for many.

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Reposted by KruegerLab

Taghon Lab @taghonlab.bsky.social · 14/01/2025

Our research on human γδ T cells is in collaboration with the lab of David Vermijlen @ulbruxelles.bsky.social u-cri.ulb.be/index.php?ac... In this context, he is looking for a postdoc with experience in molecular biology. Apply now to become part of the team! 👇 euraxess.ec.europa.eu/jobs/306959

euraxess.ec.europa.eu

Post-doctoral fellow molecular biology/immunology

The ULB Center for Research in Immunology (U-CRI) (Belgium) brings together researchers from the ULB (Université Libre de Bruxelles) Faculties of Sciences, Medicine and Pharmacy.

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KruegerLab @kruegerlab.bsky.social · 05/01/2025

This was a joint effort of our lab spearheaded by Heike Kunze-Schumacher and @probertimmodels.bsky.social and great collaborators including @victorgreiff.bsky.social and Michael Meyer-Hermann. Thanks to @dfgpublic.bsky.social for their continuous support!

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KruegerLab @kruegerlab.bsky.social · 05/01/2025

Taken together, we provide a framework to quantitatively determine cell cycle phase duration in vivo, which can be applied to a broad variety of biological systems.

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KruegerLab @kruegerlab.bsky.social · 05/01/2025

We showed that thymocyte cell cycle phase progression is heterogeneous and that, in a model of irradiation induced involution followed by endogenous regeneration, cell cycle re-entry and G1 shortening promote thymus regeneration.

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KruegerLab @kruegerlab.bsky.social · 05/01/2025

We discovered that a stretch model of simultaneous expansion or contraction of G1 and S phases explains steady-state thymocyte cell cycle speed transitions.

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KruegerLab @kruegerlab.bsky.social · 05/01/2025

We combined sequential dual-nucleoside pulse labeling and DNA content analysis with two different agent-based mathematical models to map cell cycle phase durations in thymocytes in vivo.

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KruegerLab @kruegerlab.bsky.social · 17/12/2024

Well. Perfect Q. Bullet proof glass yes. Jewish elementary school in Germany.

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KruegerLab @kruegerlab.bsky.social · 25/05/2024

None of this would have been possible without the fun and productive collaboration with the Zarnack lab at Goethe University Frankfurt. Thanks go out as well to our funders @dfgpublic.bsky.social (CRC902 and RTG2355).

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KruegerLab @kruegerlab.bsky.social · 25/05/2024

Main conclusion: Functional analysis of miRNA binding sites in physiologically relevant context massively expands the pool of miRNA-mRNA interactions.

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KruegerLab @kruegerlab.bsky.social · 25/05/2024

Prominent 3' binding in MREs exists and contributes to miRNA functionality in a complex manner.

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KruegerLab @kruegerlab.bsky.social · 25/05/2024

We also uncovered a group of target sites associated with repeat regions in KZFP Zn-finger transcription factors, which behave differently. Located predominantly in the CDS, they act through translational repression.

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KruegerLab @kruegerlab.bsky.social · 25/05/2024

There are many more binding sites than are predicted in silico. While established targeting rules apply in general, we identified many functional non-canonical MREs. We uncovered a prominent mismatch in the seed match, which retains functionality, thus extending the pool of targets substantially.

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KruegerLab @kruegerlab.bsky.social · 25/05/2024

Using combined oligo-enriched eCLIP, RNAseq and ribosome profiling, we wanted to identify functionally relevant targets of miR-181. What did we learn?

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KruegerLab @kruegerlab.bsky.social · 25/05/2024

It's finally out: academic.oup.com/nar/advance-articl… Our map of miRNA miR-181 binding sites in thymocytes:

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KruegerLab @kruegerlab.bsky.social · 14/11/2023

Congrats to Marco and Hanna, who received their M.Sc. diplomas! Excellent work by both of them!

M.Sc. students Hanna and Marco from the Krueger lab

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KruegerLab @kruegerlab.bsky.social · 25/10/2023

Thymus aficionados, mark your calendar for ThymE 24, the conference on T cell and thymus biology, May 27-31, 2024. More information will follow soon.

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KruegerLab @kruegerlab.bsky.social · 07/10/2023

Finally, KruegerLab is here as well. We are interested in all things developmental immunology, T cells (mostly unconventional), miRNA and quantitative biology.

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