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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 25/09/2026

Niche topic alert 😀: macroscopic examination of mandibular resections performed for odontogenic tumors #PathSky #ENTPath #HeadNeckPath #PathTwitter #EmoryPathology #Pathology #PathologyOutlines

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Reposted by Kelly Magliocca DDS, MPH

Alexander Nader, Einschauer, Pathologist @alexnader.eurosky.social · 09/06/2026

www.cytoinfect.com Very nice atlas on cytology of various infectious diseases, plase have a look at it #pathsky

cytoinfect.com

Cytological atlas of infectious diseases>

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 16/01/2026

50s yom maxillary sinus Dx: sinonasal papilloma, inverted-type 📸macro: partially translucent mass w/cerebriform opaque infoldings 📸low: downward growth of epi 📸 mucous cells (arrow) & microabscess formation 📸 thick squamous epi w/transmigrating neutrophils #Pathsky #Otosky #ENTsky #macromicropath

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 13/01/2026

60’s male, parotid mass Dx: Warthin tumor 📸macro: cystic-solid mass, note layering of cystic contents for gross-micro correlate [arrow] 📸low mag overview [arrow for gross-micro reference] 📸papillary projections w/lymphoid stroma 📸bilayered oncocytic epithelium #PathSky #Otosky #PathTwitter #ENTsky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 05/12/2025

Permanent slide sections of this parotid mucoepidermoid carcinoma (MEC) better demonstrate areas of oncocytic/oncocytoid change. Intermediate cells smaller, more hyperchromatic. Mucous cells scattered throughout. Note: identification of all 3 cell ‘types’ is not required for a dx of MEC. #PathSky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 05/12/2025

Higher magnification of the original frozen section slides: infiltration with aggressive growth pattern, squamoid/oncocytic nests, foci with mucous cells. Tumor is high-grade. MAML2 rearrangement detected by FISH. Frozen-section-Friday

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 05/12/2025

40’s FM parotid mass Dx: mucoepidermoid ca 📸 macro: ill defined borders, largely solid, focal cystic (arrowhead). Parotid node (solid arrow) and skel.muscle (open arrow) 📸 touch prep: clusters polygonal cells w/dense cytoplasm 📸 scan mag appearance #PathSky #ENTSky #Radsky #Otosky #PathTwitter

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 02/12/2025

40s male w/fullness & pruritus of left external auditory canal. Exam with gray-white material (removed), tympanic membrane intact. Dx: Otomycosis 📸 low mag profile of fungus ball 📸 fruiting body among hyphae & detached keratin debris 📸 addit’l fruiting bodies (Aspergillus sp) #PathSky #Otosky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 02/12/2025

Mid-40’s male w/nasal obstruction Dx: allergic fungal sinusitis (polyps not shown) 📸 layering of mucin, cellular debris, degranulated eosinophils & inflammatory cells 📸 Charcot-Leyden crystals (arrows) 📸 occasionally fungal forms visible on H&E (arrow) 📸 fungus readily highlights w/GMS #PathSky

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Reposted by Kelly Magliocca DDS, MPH

PathologyOutlines.com @pathologyoutlines.bsky.social · 26/11/2025

Image of the Week! Contributed by: Kelly Magliocca, D.D.S., M.P.H. Textbook topic: Mandible & maxilla Diagnosis: Ameloblastic carcinoma Textbook topic link: www.pathologyoutlines.com/topic/mandib... #Pathology #PathologyOutlines #PathSky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 22/11/2025

📸 Amazing how the background parotid tissue fills in so nicely on permanent sections (it is the same block! I promise!) Can better appreciate variations in cellularity and patchy hemorrhage that contribute to the gross appearance 📸 chondroid matrix, ducts and myoeps on permanent sections #PathSky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 21/11/2025

📸 frozen section, tumor capsule 📸 frozen section, epithelial cells (ducts) and myoepithelial cells 📸 frozen section, nests of myoepithelial cells in myxochondroid matrix Dx: pleomorphic adenoma #Pathsky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 21/11/2025

Frozen-section-Friday: Adult with 2 cm parotid mass sent for intraoperative consultation 📸: solitary, largely circumscribed, cut surface w internal heterogeneity 📸: touch prep - monotonous cells (myoeps) w/i basophilic matrix 📸: low mag nodule contour at frozen section …next #PathSky #ENTsky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 09/11/2025

Folliculocentric dyskeratotic process w/warty surface keratosis, suprabasal clefting, villous rete & dyskeratotic cells [corps ronds (round) and grains (flat)] #dermpath #Pathsky #ENTsky #Otosky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 09/11/2025

Partial auriculectomy for basal cell carcinoma (not shown) in pt with known history of Darier disease 📸 macro: portion of helix, formalin-fixed with multiple punctate lesions (arrow) and small plaques 📸 macro, cut-surface: firm, rust/white colored plaques confined to epidermis #dermpath #Pathsky

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Reposted by Kelly Magliocca DDS, MPH

Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 26/07/2025

Parasagittal section through total laryngectomy specimen resected for advanced stage squamous cell carcinoma. Curious finding in the blue box #PathSky #Pathology #ENTPath #HeadNeckPath #EmoryPathology

ThC: thyroid cartilage, FC: false cord, TC: true cord, ELE: extralaryngeal extension

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 06/11/2025

B: bacteria in the low mag picture. Pt likely has an underlying laryngeal chondronecrosis.

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Reposted by Kelly Magliocca DDS, MPH

Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 26/07/2025

These tyrosine-like crystalloids seem to localize most frequently to the true cord, particularly near the macula flava PMID: 39177813

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 06/11/2025

Biopsy of anterior true vocal cord, sent for intraop consult. Pt with history of glottic squamous cell ca, s/p radiation therapy. Biopsy neg for scca. However… 📸 tyrosine-like crystalloids w/i anterior macula flava (is chondroid here) 📸 TLCs not commonly seen at frozens PMID: 39177813 #Pathsky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 03/11/2025

Adult male; White corrugated plaque on lateral oral tongue Dx: oral hairy leukoplakia Low: epithelial hyperplasia, shaggy corrugated parakeratotic surface, often pallor in spinous layer High: perinuclear clearing, nuclear beading EBV ISH (red): nuclear signal in affected cells #PathSky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 27/10/2025

Solitary, exophytic nodule at posterior dorsal tongue. Dx: lingual osseous choristoma 📸: oral mucosa with central focus of dense lamellar bone 📸: relation of bone to overlying oral squamous epithelium 📸: lamellar bone (slightly over-decal’d) with evidence of remodeling #PathSky #ENTsky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 27/10/2025

Mid-30’s FM w/progressive conductive hearing loss. Clin dx: otosclerosis Intraop: stapes fixed, remainder of ossicular chain mobile. 📸: stapes with remodeling, transected above footplate 📸: evolving pseudocyst w/i the articular surface (reactive) #PathSky #ENTpath #PathTwitter #EmoryPathology

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 20/10/2025

📸Transverse section through the cricoarytenoid joint (CAJ) of the larynx, a true synovial joint. Arrows delineate joint space 📸 Same, just higher mag 📸 Generally surfaced by fibrocartilage (but may be mixed). Synovium present 📸 Synovial lining #PathSky #ENTPath #PathTwitter #EmoryPathology

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 13/10/2025

Pathologic staging = pT4a related to bone invasion (focally invades into submucosa/mucosa of maxillary sinus, no impact on pathologic stage though).

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 13/10/2025

Squamous cell carcinoma of the edentulous alveolar ridge and palate. Cut surface (ms=maxillary sinus; nc=nasal cavity); corresponding low mag image; endophytic (arrow) with cystic cuniculatum-like growth; additional cystic change in scca. #PathSky #ENTPath #HeadNeckPath #OralPath #PathTwitter

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 19/08/2025

This particular case is high grade. 📸 tumor necrosis, solid growth, and increased mitotic rate (3 in this high power field alone). 📸 EWSR1 break apart FISH positive #PathSky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 19/08/2025

Nasopharyngeal mass, adult male. Dx: Hyalinizing clear cell ca. ➡️Nests of eosinophilic and/or clear cells. Helpful: 2 ‘types’ of fibrosis (dense hyalinization and fibrolamellar stromal fibrosis). #PathSky #ENTsky #HeadNeckSky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 15/08/2025

Expansile sinonasal mass, adult FM: Dx: Epithelial-myoepithelial carcinoma. Biphasic salivary gland carcinoma composed of tightly coupled eosinophilic ductal cells and abluminal myoepithelial cells. Diffuse RAS Q61R IHC expression supportive while working thru the ddx. PMID: 33481388 #PathSky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 13/08/2025

Adult FM with temporomandibular osteoarthritis Dx: Subchondral cyst (SC) SC identified on sagittal CT & subsequently on microscopic examination. 📸➡️ TMJ SC is spherical subchondral lesion w/myxoid change surrounded by reactive bone. Articular cartilage with degenerative changes. #PathSky #RadSky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 11/08/2025

DICER1-associated atrophic changes in this min. invasive FTC. Rim of pale, flattened tumor cells adjacent to non-affected tumor. Circumferential, no cellular debris, apoptotics or inflammation; argues against necrosis. 🙌 🙏 to author KV in PMID:38637342 for teaching me! #PathSky #Thyroid #Endosky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 09/08/2025

Lytic lesion of mandible, prior extraction site; years ago. Myospherulosis represents altered RBCs in cyst-like spaces, surrounded by fibrosis. At high magnification, note the pigmented spherical bodies (‘bag of marbles’). Potentially a fungal mimic ➡️ PAS/GMS neg. #PathSky #OralPath #PathTwitter

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 08/08/2025

Hello! I’m an oral, head and neck pathologist and like to be included pls

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 08/08/2025

Concentric layers of bacteria and debris: pics➡️Center of the calculus; layered regions; and two pics demonstrating the peripheral textured region of the calculus that originally caught my eye macroscopically

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 08/08/2025

Submandibular sialolith is a gross-only specimen for us. However…the interesting surface texture piqued my interest. Intact appearance, sectioned, faxitron (in our lab) and low mag histology with arrows highlighting the textured region. #PathSky #RadSky #OralPath #ENTPath #HeadNeckPath

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 08/08/2025

SNP may (or may not?!) be distracting at intraoperative consultation. Below, an incidental focus in a en face margin of posterior-lateral oral tongue. The epithelium with taste buds is only a few layers thick and lacks a substantial surface keratin layer. Neural elements tough to see. #PathSky

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 07/08/2025

Will find SNP tissue (arrows in these two low magnification examples) near fungiform, foliate and/or circumvallate papillae of the tongue. #PathSky #ENTPath #OralPath #HeadNeckPath #PathTwitter

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 07/08/2025

At high magnification, subgemmal neurogenous plaque (normal regional microanatomy) may overlap with neurofibroma: spindle cells, buckled nuclei, collagenous stroma. Key clue: localization near taste buds (s100+/keratin+) in the overlying epithelium.

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 06/08/2025

Sinonasal mass, adult. DEK::AFF2 sinonasal carcinoma, FISH+. We do not have this testing in-house, we used a reference lab in the US for this case. (Attached ancillary testing results were non-specific) Other sites: Middle ear/temporal bone: PMID: 32366754 Larynx PMID: 40299135 Lung PMID: 35773081

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 04/08/2025

Tracheal adenoid cystic carcinoma. At high magnification (next 2 pics), areas of ‘signet-ring like’ or vacuolated, clear cell change is noted in ducts. Unknown clinical significance but when present in small biopsy material, may lead to diagnostic uncertainty. PMID: 23379326 PMID: 39235305 (fig 3)

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Kelly Magliocca DDS, MPH @kmagliocca.bsky.social · 29/07/2025

Idiopathic gingival papillokeratosis with crypt formation. Uncommon. Generally located along anterior maxillary gingiva in young people. Asymptomatic plaque(s), usually bilateral and white in color. No known risk of transformation. PMID: 28089460 #PathSky #OralPath #ENTPath #EmoryPathology