iiinova — where your digital self keeps evolving

Kirkstall Ltd @kirkstall.bsky.social · 10/09/2026

The Human Specific Research Community North launched in Bradford last week — a regional network for researchers moving to human-specific methods, set up by Animal Free Research UK. Kirkstall's Malcolm Wilkinson was there. humanspecificresearch.org/human-specific-research-community-north

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Kirkstall Ltd @kirkstall.bsky.social · 01/09/2026

Kirkstall is named among the ten key companies in DelveInsight's Organ-on-Chip market report, which values the sector at $0.52bn in 2025 rising to $3.10bn by 2034, a 22% CAGR. Quasi Vivo is cited in the liver segment, the largest at 29%. delveinsight.com/report-store/organ-on-chip-market

delveinsight.com

Organ-on-Chip Market Size, Outlook, Forecast, Insights by 2034

The global Organ-on-Chip market is projected to grow from USD 0.52 billion in 2025 to USD 3.10 billion by 2034, registering a 22.0% CAGR during 2026–2034.

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Kirkstall Ltd @kirkstall.bsky.social · 21/08/2025

92% of drugs that pass animal tests fail in humans. 🚫 The cost? Years of research + billions wasted. Human-on-chip models like Quasi Vivo® give data that actually translates. #DrugDiscovery #OrganOnChip #MPS

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Kirkstall Ltd @kirkstall.bsky.social · 15/08/2025

Your body is a system, not isolated parts. Quasi Vivo® connects multiple organs under gentle, lifelike flow, revealing interactions single-organ models miss. Model the whole, not just the parts. #OrganOnChip #HumanOnChip #MPS

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Kirkstall Ltd @kirkstall.bsky.social · 04/08/2025

Metastasis causes 90% of cancer deaths, yet remains incredibly hard to study because lab models can't accurately replicate tumour spread between human organs. A new approach could finally change this. #CancerResearch #Metastasis #OrganOnChip #Innovation

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Kirkstall Ltd @kirkstall.bsky.social · 23/07/2025

Every 90-day drug safety study can sacrifice 80 animals—but there’s a better way. Kirkstall's Quasi Vivo® offers low-shear, human-cell systems, accurately modeling human biology without animals. Discover ethical, reliable research at: kirkstall.com #AnimalFreeResearch #QuasiVivo #OrganOnChip

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Kirkstall Ltd @kirkstall.bsky.social · 18/07/2025

Pushing organ-on-a-chip from cool demo to everyday research tool takes shared standards everyone can trust. 🧬⚙️ Kirkstall dives into why harmonised protocols and familiar well-plate formats will boost reproducibility and cut reliance on animal tests. kirkstall.com/supporting-e...

kirkstall.com

Supporting Emerging Standards for Organ on a Chip - Kirkstall Ltd

Organ-on-a-chip (OOAC) and microphysiological systems (MPS) are revolutionising in vitro biology and new challenges. Read more.

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Kirkstall Ltd @kirkstall.bsky.social · 04/07/2025

Perfusion flow cell culture brings lab experiments closer to real-life conditions. 📚 One key insight: Cells thrive when nutrient flow and waste removal mimic the body's natural environment. 🔗Our article explains why this matters for your research: kirkstall.com/an-introduct...

kirkstall.com

An Introduction to Perfusion Flow Cell Culture - Kirkstall Ltd

This simple guide is designed for cell biologists who are newcomers to the use of perfusion systems for cell culture.

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Kirkstall Ltd @kirkstall.bsky.social · 23/06/2025

MPSs bridge critical gaps between lab models and human biology. To unlock their full potential, the field must focus on: • Multi-organ integration • Patient-derived cells for personalised insights • Clinical validation for real-world relevance #MPS #PrecisionMedicine

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Kirkstall Ltd @kirkstall.bsky.social · 16/06/2025

🕰️ New review shows how “ageing-on-a-chip” tech can model decades of biology in weeks. Low-shear perfusion & multi-organ flow are key — exactly what Quasi Vivo’s plug-and-play milli-fluidics deliver. Ready to study senescence without mice? 👇 advanced.onlinelibrary.wiley.com/doi/10.1002/...

advanced.onlinelibrary.wiley.com

Aging on Chip: Harnessing the Potential of Microfluidic Technologies in Aging and Rejuvenation Research

This review highlights recent advances in microfluidic technologies for modeling human aging and age-related diseases. It explores how organ-on-chip platforms improve physiological relevance, enable ...

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Kirkstall Ltd @kirkstall.bsky.social · 04/06/2025

📚 New MPS Roadmap: A fresh review (Hartung et al., ALTEX) outlines challenges holding back organ-on-chip adoption: need for standards, validation benchmarks, regulatory clarity, data sharing… and calls for global collaboration to solve them. Essential read for OOC folks! 🔗 doi:10.14573/altex.2504091

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Kirkstall Ltd @kirkstall.bsky.social · 30/05/2025

🔬 New Nature study: an 18-organ “body-on-a-chip” links heart, liver, brain & more via microfluidic blood flow + excretory loop. Stable for 2 months, reproducing human PK & toxicity across tissues—huge leap for complex in-vitro testing www.nature.com/articles/s41...

nature.com

An eighteen-organ microphysiological system coupling a vascular network and excretion system for drug discovery - Microsystems & Nanoengineering

Microsystems & Nanoengineering - An eighteen-organ microphysiological system coupling a vascular network and excretion system for drug discovery

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Kirkstall Ltd @kirkstall.bsky.social · 11/04/2025

🎯 From liver & brain to tumour microenvironment —Quasi Vivo does it all. Modular circuits 🔁 link multiple organs to realistically study systemic diseases like diabetes right on your benchtop. Healthy tissues, predictive human data, and powerful simplicity in one system.

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Kirkstall Ltd @kirkstall.bsky.social · 06/04/2025

🧱 Imagine organ-on-a-chip tech as simple as a LEGO kit! Quasi Vivo’s plug‐and‐play, modular design lets you set up advanced 3D cell cultures in minutes. ILow-shear flow keeps tissues thriving, minus the hassle of complex fabrication. Explore more at kirkstall.com

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Kirkstall Ltd @kirkstall.bsky.social · 19/03/2025

AI-driven drug discovery is rapidly generating countless new molecules. Microphysiological systems are essential to quickly and reliably evaluate their safety and effectiveness, accelerating precision medicine and advancing research. 📖 pmc.ncbi.nlm.nih.gov/articles/PMC...

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Kirkstall Ltd @kirkstall.bsky.social · 27/02/2025

🐾 It’s time to replace animal testing! Join us at the Best Practice in Non-Animal Methods Conference 2025, where Prof. Malcolm Wilkinson will tackle the barriers to human-relevant research. March 26-27 | 📍 York Register now 👉 humanspecificresearch.org/our-2025-joi... #HumanRelevantScience

humanspecificresearch.org

Our 2025 Joint Conference | Centre For Human Specific Research

We are excited to reveal our first jointly hosted scientific conference with three of the leading UK funders of animal replacement research; Animal Free Research UK, The Humane Research Trust and Repl...

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Kirkstall Ltd @kirkstall.bsky.social · 10/02/2025

Are research tools getting too complex for their own good? MPSs could transform drug discovery, but many are too costly, complex, or specialised for everyday labs. We believe that better science starts with: ✔️ Simpler workflows ✔️ Realistic costs ✔️ Usability first

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Kirkstall Ltd @kirkstall.bsky.social · 30/01/2025

🚀 New tech doesn’t adopt itself. Microphysiological systems must earn their place by proving: ✅ Human relevance ✅ Clear application ✅ Validation & benchmarking We are committed to these criteria, ensuring Quasi Vivo meets the standards needed for widespread adoption.

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Kirkstall Ltd @kirkstall.bsky.social · 24/01/2025

We know more about curing diseases in animals than in humans. With 90% of drugs failing in human trials after animal testing, it’s clear: animal models are outdated, inefficient, and unethical. Human-relevant systems like #QuasiVivo can save human lives and reduce animal testing.

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Kirkstall Ltd @kirkstall.bsky.social · 17/01/2025

🚨 Exciting update! Yesterday, Malcolm Wilkinson gave an inspiring talk at the #BITEG conference in Sheffield on creating physiologically relevant in vitro models. 🧬 Huge thanks to the organizers for a great event! 💡 #Kirkstall #InVitroModels #TissueEngineering #RegenerativeMedicine

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Kirkstall Ltd @kirkstall.bsky.social · 10/01/2025

Discover how Kirkstall’s bioreactor is enabling groundbreaking research on pancreatic cancer at @uclofficial.bsky.social. Professor Eirini Velliou explains how her team is studying cell behaviour and chemotherapy responses using advanced in vitro models. Full video: kirkstall.com/quasi-vivo-c...

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Kirkstall Ltd @kirkstall.bsky.social · 03/01/2025

Dr. Malcolm Wilkinson, founder of Kirkstall Ltd, will keynote at the BiTEG conference on Jan 16th at @sheffielduni.bsky.social. He’ll explore the future of in-vitro models & their role in replacing animal testing. Register here 🎉: onlineshop.shef.ac.uk/conferences-...

onlineshop.shef.ac.uk

Biomaterial and Tissue Engineering Group Conference 2025 | University of Sheffield

BITEG 2025 26th Annual White Rose Biomaterials and Tissue Engineering Group conference 2025.  The registration fee is the same for all delegates and t

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Kirkstall Ltd @kirkstall.bsky.social · 23/12/2024

🌟 We’re excited to join the Bluesky community! At Kirkstall, we’re advancing research and industry with Quasi Vivo® systems, providing ethical, innovative alternatives to animal testing. #DrugDiscovery #OrganOnChip #Innovation #PersonalisedMedicine #MicrophysiologicalSystems

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