Sign in

Katie Houlahan

@khoulahan.bsky.social
36 followers 85 following 25 posts

Assistant Professor @ McMaster University. Studying the impact of inherited DNA variants on tumour evolution.

PostsRepliesMedia
Reposted by Katie Houlahan
Noah F. Greenwald @noahgreenwald.bsky.social · 29/01/2025
I’m super excited to share what I’ve been working on for the last (many) years: a spatial + genomic + transcriptomic characterization of how the breast cancer microenvironment evolves through immunotherapy! (1/x) 🧪🧬 🖥️ #AcademicSky #MLSky #ImmunoSky www.biorxiv.org/content/10.1...
biorxiv.org
Temporal and spatial composition of the tumor microenvironment predicts response to immune checkpoint inhibition
Immune checkpoint inhibition (ICI) has fundamentally changed cancer treatment. However, only a minority of patients with metastatic triple negative breast cancer (TNBC) benefit from ICI, and the deter...
23313
Katie Houlahan @khoulahan.bsky.social · 08/01/2025
The Curtis Lab’s latest study on the genomic architecture of breast cancer from the pre-invasive to metastatic setting is now out in Nature! www.nature.com/articles/s41...
nature.com
Complex rearrangements fuel ER+ and HER2+ breast tumours - Nature
A study identifies three dominant genomic archetypes of breast cancer induced by discrete mutational processes, describing a continuum of genomic profiles and detailing the mechanisms underlying the p...
3189