New paper out in JBMRPlus !
Using a time-lapse co-culture approach with #osteoclasts and reversal cells, we show that reversal cells prefer pits over trenches, but that intermediate #CatK inhibition boosts their attraction and maturation into #osteoblasts.
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Cathepsin K inhibitors promote osteoclast-osteoblast communication and engagement of osteogenesis
Abstract. Cathepsin K inhibitors are well known for their inhibitory activity against bone resorption but were also reported to preserve bone formation in