iiinova — where your digital self keeps evolving

Kelly Perlman @kelperl.bsky.social · 26/06/2026

Thank you @xprize.org for the incredible opportunity to have participated in the #IBMWatsonAIXPrize and for your unwavering support over the years!

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Kelly Perlman @kelperl.bsky.social · 16/05/2026

Thank you Naguib! I am so lucky to have had such an incredible mentor 🧠😊

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Kelly Perlman @kelperl.bsky.social · 16/05/2026

These changes to lipid-lipid and lipid-protein interactions likely contribute to age-related myelin deficits and may help explain cognitive decline as we age. A huge thank you to @naguibmechawar.bsky.social and to our wonderful Bluesky-less co-authors 😊 🧵 4/4

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Kelly Perlman @kelperl.bsky.social · 16/05/2026

In contrast, we found pronounced age-related shifts in phospholipid composition. The overall pattern showed ⬆️ MUFAs and ⬇️ long-chain omega-6 PUFAs with age. We also observed decreased expression of myelin-constituent genes and proteins with age, correlating with the lipid quantities. 🧵 3/4

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Kelly Perlman @kelperl.bsky.social · 16/05/2026

Interestingly, we did not identify robust molecular correlates of the long-lasting impacts of early life adversity, as we had previously seen in the anterior cingulate cortex, suggesting regional specificity to these effects. 🧵 2/4

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