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Katherine Pintor

@keithpint.bsky.social

14 followers 27 following 0 posts

Postdoctoral fellow, UC Berkeley PhD Microbiology, Max Planck Institute for Terrestrial Microbiology

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Reposted by Katherine Pintor

Diepold Lab @diepold-lab.bsky.social · 20/08/2025

Using live-cell microscopy, we uncovered distinct bacterial subpopulations that primarily use certain combinations of these nanomachines: • some prioritize motility & T3SS • others shift to T6SS for antagonism All tuned by the usual suspect: cyclic di-GMP.

That's how we think Pseudomonas aeruginosa uses the T3SS, H1-T6SS, and flagellum during infection.

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Reposted by Katherine Pintor

Diepold Lab @diepold-lab.bsky.social · 27/08/2025

We recently described how T3SS effectors reach the injectisome with a shuttle system. But what about their chaperones? With live microscopy, proximity labeling and functional assays, @keithpint.bsky.social showed the Yersinia chaperone SycH already hands over its cargo in the cytosol. bit.ly/47hq6rM

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