iiinova — where your digital self keeps evolving

Yeah, psychopaths everywhere!

I hope the “being rude to AI is a slippery slope to being a murderer” folks that assert that if you’re willing to kill any life form, you’re more likely to be willing to kill people never find out how many plates of bacteria I’ve put into autoclaves.

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Kai Blin @kblin.bsky.social · 7h

And now I found the thread this will be a subskeet of. That makes this even more fun.

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Kai Blin @kblin.bsky.social · 7h

Ah, fun memories of accidentally using the BFG on init

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Kai Blin @kblin.bsky.social · 08/10/2026

As a child, that sounded crazy. After two decades in academia, I'm no longer surprised.

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Kai Blin @kblin.bsky.social · 08/10/2026

We talked about this in school, and from what I remember, many academics did more than just turn a blind eye. Many joined the NSDAP when it looked like this step would positively affect their funding.

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Kai Blin @kblin.bsky.social · 08/10/2026

The language recommended by the HHS.

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Kai Blin @kblin.bsky.social · 04/10/2026

And here I thought a Labrador would be looking for a postdog.

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Kai Blin @kblin.bsky.social · 03/10/2026

Well, I asked ChatGPT, and here is what it said the video is about….. Mastodon can be so cliché at times.

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Kai Blin @kblin.bsky.social · 30/09/2026

Came into the replies to say that, so I can only agree emphatically.

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Reposted by Kai Blin

Os Keyes @okeyes.bsky.social · 15/09/2026

Since we’re doing another round of “AI will destroy humanity” doom-hype, it’s a good time to announce a new paper myself and my postdoc advisor just had accepted by BioSocieties on just this. TL;DR: almost all the “AI can make bioweapons” literature comes ultimately from the Effective Altruists.

ironholds.org

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Kai Blin @kblin.bsky.social · 25/09/2026

True. But seeing how hosted solutions can cost more money per month than a VPS costs per year, having a script run automatic updates is usually worth it. For hosted solutions, I guess Heroku is still around. Or I guess Vercel and Cloudflare host JS projects specifically.

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Kai Blin @kblin.bsky.social · 25/09/2026

Personally, I'd go for a cheap VPS and just install stuff. You have full control over your stack then.

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Kai Blin @kblin.bsky.social · 17/09/2026

Somebody at Apple must have forgotten to add "no mistakes" to their prompt.

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Kai Blin @kblin.bsky.social · 15/09/2026

It's certainly more environmentally friendly because it immediately broke printing for me. Print something? Not now.

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Kai Blin @kblin.bsky.social · 15/09/2026

I’ll get a bunch of reminders, and then a final “we needed to proceed without you”. And likely the authors will need to wait longer to get their manuscript reviewed.

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Kai Blin @kblin.bsky.social · 15/09/2026

I was in a thread on here recently discussing how editors are struggling to even get people to decline invites. I just got an invite from Food Biotech that requires me to create an Elsevier account to decline. It takes me one click to delete an email. Don't make it take > 3 clicks to decline.

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Kai Blin @kblin.bsky.social · 14/09/2026

Wait, no, scratch that, it’s not a subscription. You rent the toaster with a GPU in it, that runs a bit of compute for one of the frontier labs, and for the toaster rent, you get discounted tokens from said AI lab. Off to found my startup.

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Kai Blin @kblin.bsky.social · 14/09/2026

What is we made a toaster that ran a local AI model to check if the toast was done, and we use the heat from running the model to toast the toast

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Kai Blin @kblin.bsky.social · 13/09/2026

I don't think I have ever seen "cream on top" before, hence why I was asking.

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Kai Blin @kblin.bsky.social · 13/09/2026

If brute force doesn't work, you're not using enough of it. 😉 But fair enough, I'd use the same

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Kai Blin @kblin.bsky.social · 13/09/2026

I guess whatever keeps those people away from raw milk is fine. If there is enough air in your bottles, vigorously shaking it before opening should break up the worst clumps. If it tastes good and doesn't trigger your immune system, that sounds easier than home-pasteurisation.

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Kai Blin @kblin.bsky.social · 13/09/2026

Is "cream on top" a way to say "non-homogenised"? My in-laws buy organic milk that uses the latter term to advertise. Apparently, people like the "less processing, closer to the farm" feel, and I've heard people talk of supposed health benefits that are very [citation needed].

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Kai Blin @kblin.bsky.social · 11/09/2026

It just depends on how tight you define "possible efforts." Fable "safety filters" refused all requests I had with the word "microbial" in there. I can totally imagine Anthropic counting every triggering of the biosafety filter as a "possible attempt."

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Reposted by Kai Blin

Claus Wilke @clauswilke.com · 03/09/2026

The reason Claude did well at binder design is because the prompt hardcoded that it should use ESMFold2 for scoring, and apparently ESMFold2 is really good. It's also only a few months old so not widely used yet. AI in biology keeps disappointing. blog.genesmindsmachines.com/p/anthropic-...

blog.genesmindsmachines.com

Anthropic has not solved the peptide-binder design problem, but maybe bi[o]hub has

The protein design field is getting pushed forward by human experts in protein design, who would have thought

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Kai Blin @kblin.bsky.social · 08/09/2026

I think it's rich that the company that not only failed to airgap its cybersecurity benchmark network, but also didn't even bother to monitor it or install current patches keeps talking about how we need to buy their products to improve our system security.

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Kai Blin @kblin.bsky.social · 07/09/2026

Why, yes, I would like to know more.

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Kai Blin @kblin.bsky.social · 02/09/2026

I have to be honest, if the invite reads like they didn't spend 15 seconds to make sure that manuscript was in my area of expertise, I'm struggling to spend my time responding. Also, if your invite requires me to create an account just to decline, I'll be deleting that email.

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Kai Blin @kblin.bsky.social · 02/09/2026

Yeah, funnily enough you can turn those permissions off for ours, and it'll still authenticate.

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Kai Blin @kblin.bsky.social · 01/09/2026

Need to take a moment to try that on the current generation, though. It's been a while.

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Kai Blin @kblin.bsky.social · 01/09/2026

I haven't tried the current generation, but I previously managed to get GPT to regurgitate some of our AGPL licensed code in a new project when prompting for that kind of functionality. Some as in a function or two. So you still could get into copyright trouble.

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Kai Blin @kblin.bsky.social · 31/08/2026

The "AI will kill everyone in the next 10 years" slots in nicely with whatever the rest of that article is

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Kai Blin @kblin.bsky.social · 31/08/2026

They look neat. One thing I would consider adding is a small "larger number is better" note, especially if you will also show charts where smaller numbers are better. Also, about 5 % of the world has a red/green colour deficiency, even higher here in Europe. I'd avoid red and green in charts.

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Kai Blin @kblin.bsky.social · 29/08/2026

Ew, thanks for the heads up...

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Kai Blin @kblin.bsky.social · 22/08/2026

Yeah, same. I was tempted to see what the hype is about, but I don't want to touch it for DHH reasons

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Kai Blin @kblin.bsky.social · 21/08/2026

Oooh, a toaster with local control that works without cloud access?

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Kai Blin @kblin.bsky.social · 20/08/2026

Whoopsies, I think my AI agent hacked someone all by itself. I hear that's the current hip excuse.

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Kai Blin @kblin.bsky.social · 17/08/2026

I guess “the dog did my homework” is a fun variation on “the dog ate my homework”

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Kai Blin @kblin.bsky.social · 14/08/2026

But have you tried having cold thoughts instead?

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Kai Blin @kblin.bsky.social · 13/08/2026

It’s a silly election from the start, with 33 joke candidates, and a bin.

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Kai Blin @kblin.bsky.social · 13/08/2026

I’m reviewing a paper and think I just found the most “bioinformatics brain” sentence/analysis I’ve ever read. Completely correct, but if you spent a microsecond thinking about the biology, also completely useless.

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Kai Blin @kblin.bsky.social · 13/08/2026

From the outside, it looks like Clacton voters can either do a very funny thing or a very silly thing.

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Kai Blin @kblin.bsky.social · 13/08/2026

I believe that’s based on prior art.

FamilyGuy skin colour chat meme with a uniformed arm holding a chart of skin colours up that lists bright skin colours as okay and dark skin colours as not okay

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Kai Blin @kblin.bsky.social · 10/08/2026

Ah, and of course they also indulge in a little slop-rewriting-to-rust, as one does. ladybird.org/posts/adopti... I guess if Firefox and Chromium are using Rust, you can't be a proper browser without.

ladybird.org

Ladybird adopts Rust, with help from AI - Ladybird

We're adopting Rust as our C++ successor language, and using AI agents to accelerate the transition.

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Kai Blin @kblin.bsky.social · 09/08/2026

Aw, damn. I didn't really follow the project, I mainly liked the idea of more browser engines and despairing about the direction Firefox/Gecko is going. w3m is looking more appealing continuously.

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Kai Blin @kblin.bsky.social · 08/08/2026

Yeah, I mainly meant that you shouldn't be using Firefox directly, just like you shouldn't use Chrome. Go for something more trustworthy using the engine you want.

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Kai Blin @kblin.bsky.social · 08/08/2026

I'm hoping for Ladybird. But not holding my breath.

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Kai Blin @kblin.bsky.social · 08/08/2026

I think Firefox-based is the way to go there, just like you'd avoid Chrome but use, e.g., Vivaldi

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