iiinova — where your digital self keeps evolving

Reposted by Jules Bouget

Raph Gaudin's team @gaudinlab.bsky.social · 23/09/2026

New work from our team: "Pharmacological targeting of bunyavirus-induced synaptic impairment prevents neuronal hyperexcitability", just published in @natcomms.nature.com ! www.nature.com/articles/s41... Proud to highlight Basia (Research Engineer) and Jules (PhD student), who co-led this work!

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Raph Gaudin's team @gaudinlab.bsky.social · 02/09/2026

Let's take a look back at June, and many congratulations to Maïka on her excellent defense! @deffieums.bsky.social obtained her habilitation to supervise research (HDR). Her projects include dissecting HBV cell entry using live imaging and identifying novel secretory pathways.

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Reposted by Jules Bouget

Raph Gaudin's team @gaudinlab.bsky.social · 25/06/2026

Emilie (postdoc in the team) and Raph represented the team at the Single Cell Symposium in Vancouver last month! @cnrsbiologie.bsky.social #singlecell

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Raph Gaudin's team @gaudinlab.bsky.social · 24/03/2026

The deadline to submit an abstract to the "Virus & Brain" workshop (2-3 June 2026 - Montpellier, France) is approaching (April 1st) : www.atoutcom.com/workshop-vir... Don’t miss this unique chance to connect with the international community and highlight your work! @inserm.fr @cnrs.fr

atoutcom.com

REGISTRATION – Virus & Brain

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Viroscope @viroscope.bsky.social · 07/03/2026

The Trojan Horse is real, and it’s microscopic! 🐴🦠 Our paper is out today in @cellcellpress.bsky.social! We discovered that deltaviruses physically hide INSIDE helper viruses to sneak into new cells. And to prove it, we had to image them from every angle. 🧵👇 www.sciencedirect.com/science/arti...

sciencedirect.com

Deltaviruses spread through a viral Trojan Horse

Hepatitis D-like satellite viruses, known as deltaviruses, have been recently discovered in a wide range of animals. These viruses are thought to expr…

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Reposted by Jules Bouget

Viroscope @viroscope.bsky.social · 07/03/2026

Using post-mortem human brain explants with @jvirolb.bsky.social and @gaudinlab.bsky.social, we could instigate RDeV replication within neural cells and show that upon VSV infection, these dual particles could be formed! Neurons in 🟢, vessels in🟣 DNA in 🟡 and deltavirus in 🔵.

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Raph Gaudin's team @gaudinlab.bsky.social · 29/01/2026

The Réseau thématique Virus-Cerveau @inserm.fr is pleased to announce that we will be organising our first 'Virus & Brain' International Workshop. @cnrs.fr 🧠Virus & Brain - 1st International Workshop 📅2-3 June 2026 📍Montpellier, France

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Raph Gaudin's team @gaudinlab.bsky.social · 15/12/2025

The PhD work of Glaucia de Almeida, currently a postdoctoral researcher in the team working on viral neuroinfections using spatial proteomics, was recently highlighted in g1 Ribeirão e Franca. g1.globo.com/sp/ribeirao-...

g1.globo.com

Como Covid e Oropouche podem antecipar risco de doenças cerebrais | G1

Pesquisa mostra que os dois vírus infectam células do cérebro adulto.

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Trends in Neurosciences @cp-trendsneuro.bsky.social · 10/12/2025

'When viral infections rewire neural circuits: towards cognitive virology' by Jules Bouget, Emma Partiot & Raphael Gaudin @jvirolb.bsky.social; @emmapartiot.bsky.social; @gaudinlab.bsky.social www.cell.com/trends/neuro...

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Université de Montpellier @umontpellier.bsky.social · 04/12/2025

#Podcast 🎧 A L'UM la science #112 : "Vers la virologie cognitive ?" 🎙️▶️ smartlink.ausha.co/a-l-um-la-sc... 🗣️ Retrouvez toutes les émissions A L'UM la science : www.umontpellier.fr/articles/tag...

smartlink.ausha.co

#112 : Vers la virologie cognitive ?

Vers la virologie cognitive ? Cette semaine dans A l’UM la science Raphaël Gaudin et Jules Bouget de l’Institut de recherche en infectiologie de Montpellier (https://www.irim.cnrs.fr/) nous parlent de...

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Jules Bouget @jvirolb.bsky.social · 12/11/2025

Viruses have evolved diverse mechanisms to cross the BBB, and crossing itself can cause damage. Notably, we question if brain invasion is required for neurovirulence, as peripheral-CNS signaling may allow non-neurotropic viruses to disrupt brain function. 6/6

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Jules Bouget @jvirolb.bsky.social · 12/11/2025

Neuroimmunity regulates neuronal activity and is responsible for viral clearance. Virus-driven disruptions in signaling pathways that link antiviral immunity and synaptic homeostasis reveal the fine balance between infection and immune response. 5/6

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Jules Bouget @jvirolb.bsky.social · 12/11/2025

By interacting with synaptic proteins and extensively reshaping the neuronal proteome, viruses remodel the molecular composition & function of synapses. We also underscore that synaptic organelles, crucial for local signaling, are primary targets of viral infections. 4/6

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Jules Bouget @jvirolb.bsky.social · 12/11/2025

Many viruses alter neuronal activity and brain connectivity, disrupting the networks essential for complex cognitive functions. Viral infections impair synaptic transmission, leading to defecits in synaptic plasticity processes critical for memory formation and consolidation. 3/6

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Jules Bouget @jvirolb.bsky.social · 12/11/2025

Clinical evidence suggests that severe and mild cognitive impairments can result from viral infections, sometimes lasting long after acute illness. Cognitive virology provides a framework integrating neurovirology, neuroimmunology, and neurobiology to examine viral impacts on human cognition. 2/6

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