SapKrap @justanonymous.bsky.social · 29/09/2026Out of curiosity I looked up the researchgate of the friend I mentioned, and they have 19 authorships (not including posters/platforms). Looking at the peers and recent grads of the same medical school (that I could find online) and the range is between 1 to 20s. I guess it's context dependent. 000
SapKrap @justanonymous.bsky.social · 29/09/2026Could be! But I asked this person several times (in disbelief) and she was insistent that 30 was the number. I've also asked MD/PhD students at my institution and they've said 30 is crazy but the expectation now is for more pubs especially for competitive residencies. 100
SapKrap @justanonymous.bsky.social · 29/09/2026Depending on the field it could be a career defining amount! I don't know if it's the case at all institutions or all specialties, however. 100
SapKrap @justanonymous.bsky.social · 28/09/2026A family friend is in med school and wants to do derm. She told me the expectation for competitive applicants is 30 journal articles, so at least ten a year. I don't know any other field where this would be considered normal or acceptable. 381
SapKrap @justanonymous.bsky.social · 22/09/2026From what I've heard he was already rude, abrasive and absent when he represented the big 1st. Pat Roberts barely scraped by after his residency scandal so I'm not sure what Roger was thinking. If the polling with Cindy H is to be believed Roger really is a legendarily bad candidate 010
SapKrap @justanonymous.bsky.social · 21/05/2026You can't really understand your structure and what it means unless YOU actually model it and think about it. Thinking back years ago, an elder xtalographer told me that phenix autobuild ruined a generation of structural biologists. Don't think there is a direct equivalency to this moment though. 000
SapKrap @justanonymous.bsky.social · 28/03/2026He's just trying to get a slice of the Rod Dreher electorate 000
SapKrap @justanonymous.bsky.social · 27/01/2026Allscripts? I'm not sure. This is very complex software that has no forgiveness for failure in a very regulated environment. Brent Shafer basically destroyed Cerner through contempt for human capital and this was compounded by the people from Oracle. I don't think old Cerner is recoverable. 251
SapKrap @justanonymous.bsky.social · 11/01/2026I'm reliant on 1.2/1.3 300 mesh; any deviations I can't really work around. I know SubAngstrom was making 1.8/2 300 mesh some time back, I wonder if they're making other sizes now. Also, Single Particle LLC offered good pricing for ANTcryos last I asked, maybe it would be worth getting some... 000
SapKrap @justanonymous.bsky.social · 11/01/2026Same experience! I did get some trial packs from Mitegen but they were fragile and required optimization beyond my patience. Lots of torn squares but I did get some nice particles. 010
SapKrap @justanonymous.bsky.social · 19/10/2025I had something growing in a SDS stock solution years back and I just put it in the back of a drawer. If you want to grow in a 10% surfactant solution you deserve respect. 030
SapKrap @justanonymous.bsky.social · 11/10/2025She would be 79 if elected. I don't know what victory Chuck thinks he has here. Not since the 1920s or Reconstruction has the Democratic party had such sclerotic and weak leadership. www.axios.com/2025/10/09/u...axios.comScoop: Janet Mills to launch Senate bid Tuesday, per internal documentMills' entrance into the race is also likely to set off a divisive primary contest. 010
SapKrap @justanonymous.bsky.social · 25/04/2025www.nature.com/articles/d41... Never knew you could use worms for expression!nature.comA protein tunnel that shuttles lipids around the cellThe high-resolution structure of a ‘superhighway’ for lipids in cells has been obtained. 010
SapKrap @justanonymous.bsky.social · 26/03/2025Absolutely appalling, so sorry to hear this Jason. 030
SapKrap @justanonymous.bsky.social · 22/03/2025My 4 y/o told me something no parent ever wants to hear. "I want to be a protein scientist with a microscope like you". He's too young to understand you could be a C elegans geneticist or an architect and not someone that spends weeks freezing aggregates on rare metal disks. 030
SapKrap @justanonymous.bsky.social · 13/02/2025What a stupid country www.washingtonpost.com/health/2025/...washingtonpost.comRFK Jr. confirmed, elevating anti-vaccine activist to nation’s top health postThe Senate held a final vote on whether to approve Robert F. Kennedy Jr. for Health and Human Services secretary after a three-month confirmation fight. 010
SapKrap @justanonymous.bsky.social · 07/02/2025This is really such a hopeless political party. www.rollingstone.com/politics/pol...rollingstone.comDem Overseeing 'Digital Assets' to Hold Luxury Retreat With Crypto KingpinArizona Sen. Ruben Gallego, who’s overseeing a “digital assets” committee, is set to hold a luxury weekend donor retreat with a crypto kingpin. 030
SapKrap @justanonymous.bsky.social · 04/02/2025I should have been clearer in my reply, I was referring to the paper in my post. I'm not a prolific author at all, but I have had demands where it was clear that nothing was enough for the reviewers. It appears that Mignot and Cambillau didn't have such demands from Nature for more experiments. 110
SapKrap @justanonymous.bsky.social · 04/02/2025AF has been of use at a gross level for reconstructions, but for my projects the predictions have been rather poor. I don't know enough about the subject matter in the paper, but if I were to publish something similar I would only feel comfortable with complimentary experiments to prove my points. 120
SapKrap @justanonymous.bsky.social · 31/01/2025www.nature.com/articles/s42... This is the first "all AlphaFold and nothing else" paper I've seennature.comStructural model of a bacterial focal adhesion complex - Communications BiologyThe structural model of a bacterial focal adhesion complex reveals the connection of essential functional modules throughout the cell envelope and offer an inspiring view of the force transduction mec... 271
SapKrap @justanonymous.bsky.social · 23/01/2025Old Outlook: Click calendar entry->open attachment New Outlook: Click calendar entry->opens browser window->organization SSO->opens Office 365 calendar -> click calendar entry -> you do not have permission to open this file 020
SapKrap @justanonymous.bsky.social · 07/01/2025If you're still there, Maru Maru in Papeete was a major highlight for us 100
SapKrap @justanonymous.bsky.social · 02/10/2024Every time JD Vance talks I feel an uncomfortable hum in my ears. 000
SapKrap @justanonymous.bsky.social · 26/06/2024Combining cryoEM and functional studies we found that mammalian TRPM5 exhibit unique properties and are uniquely sensitive to calcium. Coupling of MHR domains seems to influence gating, but we'll need more TRPM structures to determine this. 010
SapKrap @justanonymous.bsky.social · 26/06/2024Very happy to show the first work published from the Zubcevic Lab at KUMC. www.pnas.org/doi/10.1073/...pnas.org 110
SapKrap @justanonymous.bsky.social · 17/06/2024An entire day wasted because of Unicorn 7.1! I don't know why Cytiva needs to make the most cumbersome software. I've spoken to people at dozens of institutions who like Aktas but have hated the Unicorn install. 000
SapKrap @justanonymous.bsky.social · 09/06/2024In my hometown of Springfield, MO for the first time in a long time and the fattest man I've ever seen is wearing a shirt with an AR-15 on it that says "Socialism Preventer" 010
SapKrap @justanonymous.bsky.social · 19/05/2024Never thought I would say this, but Phenix on Windows has not crashed once this project whereas Phenix on my Ubuntu box can only run from command line. 000
SapKrap @justanonymous.bsky.social · 10/04/2024www.nature.com/articles/s41... What a delightful structural paper, so happy to see it published 000
SapKrap @justanonymous.bsky.social · 22/01/2024From Andrew Fire, Viroid-like colonists of human microbiomes www.biorxiv.org/content/10.1... 000
SapKrap @justanonymous.bsky.social · 01/12/2023www.nature.com/articles/s41...nature.comAlphaFold predictions are valuable hypotheses and accelerate but do not replace experimental structu...An analysis of AlphaFold protein structure predictions shows that while in many cases the predictions are highly accurate, there are also many instances where the predicted structures or parts of pred... 010
SapKrap @justanonymous.bsky.social · 03/11/2023Half a year wait for Quantifoils. Outrageous that wait times have never improved, only gotten worse. Has anyone ever used C-flats? Are they about the same or worse? 100
SapKrap @justanonymous.bsky.social · 02/11/2023Sometimes I have real apprehension about the future of experimental structural biology. The predictions for my proteins of interest are currently poor and some domains are nonsensically arranged. Who is to say this couldn't change in ten, maybe five years though? 000
SapKrap @justanonymous.bsky.social · 13/10/2023www.theatlantic.com/ideas/archiv... An exemplary piece really hitting home how only morons should read The Atlantic. Who on earth could possibly give a shit about what some depraved neoconservative from the Bush years thinks about the Middle East. 010
SapKrap @justanonymous.bsky.social · 03/10/2023After seeing a talk I realize how much I miss crystallography sometimes. There's nothing like shooting a poor looking crystal and getting a beautiful array of spots back. After two years of membrane proteins I also realize how much I miss soluble proteins that can be worked with. 000
SapKrap @justanonymous.bsky.social · 25/09/2023Writing a NIH BioSketch is such a humiliating exercise 020