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Julia Ritterhoff, PhD @juliaritterhoff.bsky.social · 13/08/2025

Are you on the hunt for a novel AAV vector for cardiac gene therapy? We identified a promising candidate in human heart biopsies with great potential for cardiac-directed therapies. doi.org/10.1161/CIRC...

doi.org

American Heart Association Journals

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Julia Ritterhoff, PhD @juliaritterhoff.bsky.social · 26/06/2025

First post here on a new publication from our lab 😄😄😄 I'm excited to share our latest work on cardiac gene therapy, where we show that AAV5 is effective in delivering S100A1 to the post-ischemic heart, achieving lasting improvement in cardiac performance.@dzhk.de www.ahajournals.org/doi/10.1161/...

ahajournals.org

Cardiac-Targeted AAV5-S100A1 Gene Therapy Protects Against Adverse Remodeling and Contractile Dysfunction in Postischemic Hearts | Circulation: Heart Failure

BACKGROUND: Guided by long-term safety data for AAV5 (adeno-associated virus 5) in humans, our translational study investigated whether AAV5 effectively delivers genes to healthy and achieves therapeu...

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Reposted by Julia Ritterhoff, PhD

The New York Times @nytimes.com · 15/05/2025

Breaking News: A baby with a rare disorder made medical history by receiving the first custom gene-editing treatment. The technique used has the potential to help people with thousands of other uncommon genetic diseases. nyti.ms/4j49xBy

A baby surrounded by medical devices is being held up by someone with gloved hands. A headline reads: "Baby Is Healed With World's First Personalized Gene-Editing Treatment." Photo courtesy of Children's Hospital of Pennsylvania.

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