Reposted by John SchogginsJulie Pfeiffer @jkpfeiff.bsky.social · 26/06/2026Faculty search announcement 2026: Tenure-Track Assistant Professor in Microbiology at UT Southwestern in Dallas. We seek candidates working in microbial pathogenesis (broadly defined). Come join our community! (1/5) www.utsouthwestern.edu/departments/... 34553
John Schoggins @jschoggins.bsky.social · 21/05/2025Very little here The OG is Geiss/Sen 2001 microarray - polyIC in IFN-defective cells PMID:11487589 We did microarray of lenti-cGAS (IRF3 trigger, like dsRNA) in STAT1-KO cells 2014 PMID:24284630 Irving/Wang: RNA-Seq of polyIC in IFNAR2 KO bat cells, they saw IRF1/7 signature 2020 PMID:33147460 120
John Schoggins @jschoggins.bsky.social · 09/05/2025Out now! A fresh perspective on interferon-mediated antiviral activity -- How many ISGs does it take to inhibit a virus? Perhaps far fewer than we think. dx.plos.org/10.1371/jour...dx.plos.orgOld cytokine, new tricks: A refined model of interferon’s antiviral activityInterferon is a central component of the vertebrate antiviral immune response, thought to act through induction of hundreds of interferon-stimulated genes, with some redundancy. This Perspective highl... 04513