iiinova — where your digital self keeps evolving

Jonathan Rivnay

@jrivnay.bsky.social

118 followers 124 following 11 posts

Professor of Biomedical Engineering and Materials Science & Engineering @NorthwesternU

Posts Replies Media

Jonathan Rivnay @jrivnay.bsky.social · 01/04/2026

Looking for candidates that have comfort in the front end, and/or systems level design, and can be independent in rapid iteration of prototypes. A sub-set of these skills is great, so long as you are willing to learn! BME, MSE, EE/CS, ME and related backgrounds. DM/✉️ me

000

Jonathan Rivnay @jrivnay.bsky.social · 01/04/2026

We are hiring! We’re looking for a Postdoc to take on a key role as a Postdoc in our biohybrid team. Key tasks are to design, develop, and participate in key pre-clinical studies of oxygenation technologies, and biohybrid systems such as "living pharmacies”

100

Jonathan Rivnay @jrivnay.bsky.social · 08/01/2025

But popular demand: the shareable, accessible link! rdcu.be/d5z6s

rdcu.be

Integrating bioelectronics with cell-based synthetic biology

Nature Reviews Bioengineering - Biohybrid devices based on engineered cells interfaced with bioelectronics combine the strengths of each field, resulting in constructs with properties that are not...

110

Jonathan Rivnay @jrivnay.bsky.social · 08/01/2025

We highlight the core building blocks, challenges and opportunities in integration and translation, as well as the outlook on this rapidly growing and exciting field.

020

Jonathan Rivnay @jrivnay.bsky.social · 08/01/2025

w/ landmark proofs-of-concept from the lit., we show how these bricks can come together and provide a framework. Imagine spanning more modalities (optical, mechanical, etc) to tackle hybrids that can sense their local environment, actuate, support themselves, and more.

240

Jonathan Rivnay @jrivnay.bsky.social · 08/01/2025

Think about ‘reading’ & ‘writing’ to your bioelectronic or cell-based component. We have a whole library of modalities to communicate between these realms; plus established functionality from each realm. In essence, we build a toolbox of biohybrid bricks, or biohybricks.

110

Jonathan Rivnay @jrivnay.bsky.social · 08/01/2025

We recently highlighted the potential for biohybrid therapies in Science — www.science.org/doi/10.1126/... while impactful, this only scratches the surface…

science.org

Are implantable, living pharmacies within reach?

Cell-based drug factories could produce therapies on demand inside patients

110

Jonathan Rivnay @jrivnay.bsky.social · 08/01/2025

We argue that the union of bioelectronics and cell-based synthetic biology can bring biological specificity and long range communication (with other devices, stakeholders, etc), precision timing/control, or even added functionality to these broad application areas.

110

Jonathan Rivnay @jrivnay.bsky.social · 08/01/2025

In this work we consider the synergistic role of bioelectronics, engineered cells, (and biomaterials) in assembling first-in-class biohybrid devices that could be critical for rising applications in living therapies, sensors, and biohybrid robotics for example.

110

Jonathan Rivnay @jrivnay.bsky.social · 08/01/2025

Shout out to the this awesome crew of co-authors: Omid Veiseh, Tzahi Cohen-Karni, @rituraman.bsky.social, Katie Galloway, @jacobrobinson.bsky.social, and Christian Schreib

120

Jonathan Rivnay @jrivnay.bsky.social · 08/01/2025

Just out in @natrevbioeng.bsky.social, check out our perspective on integrating bioelectronics with cell-based synthetic biology. www.nature.com/articles/s44...

nature.com

Integrating bioelectronics with cell-based synthetic biology - Nature Reviews Bioengineering

Biohybrid devices based on engineered cells interfaced with bioelectronics combine the strengths of each field, resulting in constructs with properties that are not otherwise achievable. In this Revie...

3235