Reposted by Jean-Philippe Leduc-Gaudet
Strength training improves mitochondrial bioenergetics and skeletal muscle integrity in women with Myotonic Dystrophy Type 1.
Thanks to everyone involved, notably @gillesgouspillou.bsky.social, @jpleduc-gaudet.bsky.social, E. Duchesne, L. Girard-Coté.
onlinelibrary.wiley.com/doi/10.1111/...
onlinelibrary.wiley.com
A 12‐Week Strength Training Improves Mitochondrial Respiration, H2O2 Emission and Skeletal Muscle Integrity in Women With Myotonic Dystrophy Type 1
Background
Myotonic dystrophy type 1 (DM1) is caused by expanded CTG repeats in the DMPK gene, causing the accumulation of toxic RNA that sequesters RNA-binding proteins. Clinically, DM1 is characte.....