Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 18/03/2026Kevin M. Bell & coauthors used ecological momentary assessment and wearable devices to collect real-time data in a large cohort of adults with chronic low back pain. Read more in JOR Spine: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 22/01/2026Check out recent perspective piece by Nima Ashjaee & coauthors in JOR Spine, on "Subject-Specific Musculoskeletal Modelling: The Future of Predicting and Preventing Proximal Junctional Failure in Adult Spinal Deformity": onlinelibrary.wiley.... 021
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 20/01/2026Check out "Therapeutic Approaches for Enhancing Spinal Fusion in Low Back Pain: A Review With a Focus on the Elderly", by Shuimu Chen & coauthors in JOR Spine: onlinelibrary.wiley.... 042
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 19/01/2026Xuejiu Cai & coauthors performed a meta-analysis to evaluate the diagnostic efficacy of metagenomic next-generation sequencing in infectious diseases of the spine: onlinelibrary.wiley.... 122
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 18/01/2026Check out recent review, "Advancing Intervertebral Disc Biology via Omics: Implications for Nucleus Pulposus Progenitor Cell-Based Regeneration" by Anja Stirnimann, Leon Schlagenhof, Benjamin Gantenbein, & Fabian Ille: onlinelibrary.wiley.... 031
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 18/01/2026Condoliase is a treatment for lumbar disc herniation, but its behavior in the nucleus pulposus is not clear. Ippei Watanabe, Ko Takeda & Taiichi Shirogane evaluated the properties of condoliase in the nucleus pulposus: onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 16/01/2026Chih-Wei Chen & coauthors developed lovastatin-loaded nanoparticles incorporated into thermosensitive chitosan/gelatin/glycerophosphate hydrogel for the treatment of intervertebral disc degeneration: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 15/01/2026Chronic low back pain requires precise phenotyping for tailored treatments. Zakiy F. Alfikri & coauthors introduce a mobile health system that collects biomechanics & behavior data from in-clinic and 7-day at-home assessments from 1000 individuals: onlinelibrary.wiley.... 012
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 14/01/2026Xiao Liang & coauthors developed a reliable and reproducible rat model of intervertebral disc degeneration by injecting advanced glycation end products into the intervertebral discs of ovariectomized rats: onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 14/01/2026Richard D. Bell & coauthors developed a segmentation model to identify seven distinct disc tissues and to use these segmented areas, along with other derived measures, to estimate pathological changes that align with traditional histological scoring: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 13/01/2026Mauro Alini & coauthors discuss animal models of intervertebral disc degeneration and low back pain, with an exploration of artificial intelligence in research analysis and development of prospective therapeutics: onlinelibrary.wiley.... 010
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 12/01/2026Dean Esposito & coauthors present a scoping review of MRI-based lumbar disc degeneration grading systems: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 11/01/2026A cross-tissue transcriptome-wide association study by Li Zhang & coauthors identified susceptibility genes for intervertebral disc degeneration. Learn more in JOR Spine: onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 10/01/2026Veronica Tilotta & coauthors found that Wharton's Jelly mesenchymal stromal cell-derived extracellular vesicles attenuate intervertebral disc degeneration under inflammatory stress in an in vitro 3D culture system: onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 09/01/2026Kevin M. Bell & coauthors report findings from multi-level inertial measurement unit (IMU) kinematic data collected during performance-based tests in participants with chronic low back pain: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 08/01/2026James Melrose & coauthors present a conceptual review exploring the published evidence and mechanistic rationale on naturally occurring toxins and venoms as peptide calcium channel blockers for chronic low back pain: onlinelibrary.wiley.... 132
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 07/01/2026Check out "Exploring the Biopsychosocial Impact of Chronic Low Back Pain in Workers Through Artificial Intelligence-Driven Phenotyping", by Paolo Giaccone & coauthors: onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 06/01/2026Alaina L. Falck & coauthors looked at the sensitivity of quantitative MRI techniques in detecting disc degeneration in client-owned, nonchondrodystrophic-breed dogs: onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 05/01/2026Calcium phosphate (CaP) biomaterials are widely used in surgical applications such as spinal fusion to substitute for or extend autogenous bone graft. William R. Walsh & coauthors compared three clinically available CaP-based materials: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 04/01/2026Valerio Tonelli Enrico & coauthors report the quantification of key circulatory cytokines in a chronic low back pain cohort: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 03/01/2026Carol M. Greco & coauthors present findings for "Patient-Reported Outcomes Among an Observational Cohort of Individuals With Chronic Low Back Pain": onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 03/01/2026Sara R Piva & coauthors performed a descriptive analysis of demographic and biomedical factors in a large sample of individuals with chronic low back pain. Learn more in JOR Spine: onlinelibrary.wiley.... 001
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 02/01/2026Michael J. Schneider & coauthors present findings from quantitative sensory testing in an observational cohort of adults with chronic low back pain: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 31/12/2025Vertebral tethers for growth modulation can be used to treat adolescent idiopathic scoliosis. Taylor J. Jackson & coauthors explored the relationship between vertebral body growth modulation under varying tether tension: onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 30/12/2025Check out this recent review by Hao Su & coauthors on "Central Pattern Generators in Spinal Cord Injury: Mechanisms, Modulation, and Therapeutic Strategies for Motor Recovery": onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 29/12/2025Matthew R. MacEwen & coauthors introduce the helical compliance vector, a novel measuring parameter that quantifies the orientation and magnitude of joint compliance (inverse of stiffness) by integrating kinetic and kinematic data within the helical axis framework: onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 29/12/2025Sitan Feng & coauthors developed and validated a predictive model for 1-year outcomes in cervical spondylosis patients after anterior cervical discectomy and fusion using multiple machine learning algorithms: onlinelibrary.wiley.... 010
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 21/12/2025Mitsuhiro Nishizawa & coauthors present their findings on the antibacterial properties of ultrafine-grained steel wire implants: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 20/12/2025Zhongpan Li & coauthors present a review on "Crosstalk Between Ferroptosis and Cuproptosis in Intervertebral Disc Degeneration: Mechanisms, Therapeutic Targets, and Future Directions": onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 19/12/2025Gianluca Vadalà & coauthors present a preliminary report of a randomized clinical trial of intradiscal mesenchymal stromal cell therapy for low back pain due to multilevel disc degeneration: onlinelibrary.wiley.... 030
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 18/12/2025Check out this narrative review of the role of adipokines in spinal disease by Jake M. McDonnell, Stacey Darwish, Joseph S. Butler, and Conor T. Buckley: onlinelibrary.wiley.... 021
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 17/12/2025Arthur J. Michalek & coauthors obtained unique insights into intervertebral disc adaptation by studying the complex motions of bovine tails using in vivo motion tracking and ex vivo range of motion testing: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 16/12/2025Jin Young Hong & coauthors tested epidural injections of human placental extract for its axon-promoting and pain-relieving effects in an in vitro model: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 15/12/2025Yi-Ping Zheng & coauthors examined causal relationships between gut microbiota, blood metabolites, and intervertebral disc degeneration. Read about their findings in JOR Spine: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 15/12/2025Jordin T. Marshall & coauthors investigated spatial and diurnal variations in sodium content within intervertebral disc tissue. Learn about their findings in JOR Spine: onlinelibrary.wiley.... 010
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 13/12/2025Intervertebral disc degeneration is a major cause of low back pain in both humans and dogs. Mary K. Heimann & coauthors investigated chondrodystrophic dogs as a preclinical large animal model of discogenic back pain: onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 12/12/2025Rémy Benais & coauthors evaluated a force-control experimental method to perform unconstrained load-induced subsidence testing of spinal interbody implants: onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 11/12/2025J. P. Warren & coauthors found that injection volume is a better predictor of stiffness restoration than injection force in an in vitro study of nucleus augmentation of the intervertebral disc: onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 10/12/2025Jeffrey L. Hutchinson & coauthors performed a scoping review of the role of sex hormones in cartilaginous tissues. Read about their findings in JOR Spine: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 09/12/2025Siddarth Ananth Swaminathan & coauthors performed an in silico study on the impact of habitual flexion on bone formation after spinal fusion surgery: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 08/12/2025William Anderst and coauthors used biplane radiography to measure lumbar spine intervertebral kinematics in chronic low back pain patients. Learn more in JOR Spine: onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 07/12/2025Kaiyuan Zheng & coauthors present their review of the literature on the role of macrophage polarization in intervertebral disc degeneration: onlinelibrary.wiley.... 010
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 05/12/2025Manmeet S. Dhiman & coauthors found that human disc degeneration is accompanied by a loss of anterior annulus fibrosus interlamellar matrix integrity as assessed by peel tests: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 05/12/2025Ying Zhang & coauthors found that diurnal asymmetric loading modulates cell phenotype in intervertebral disc: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 04/12/2025David J. Lillyman & coauthors engineered an extracellular matrix hydrogel, and found that it restores disc volume and alleviates axial hypersensitivity in a rat model of disc-associated pain: onlinelibrary.wiley.... 000
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 04/12/2025Timothy D. Jacobsen & coauthors found that TNFα Receptor 1 and not Receptor 2 affect annulus fibrosus and nucleus pulposus response to cytokine challenge in a rat model. Learn more in JOR Spine: onlinelibrary.wiley.... 000
Reposted by Journal of Orthopaedic Research - Spine®Orthopaedic Research Society @orssociety.bsky.social · 03/12/2025Check out this @jorspine.bsky.social Editor’s Pick: Researchers tested potassium iodide (KI) as a new contrast agent to improve micro-CT imaging of the nucleus pulposus for earlier detection of IVD degeneration. Read more: bit.ly/3XyGQVkbit.lyHigh‐Resolution 3‐Dimensional Micro‐CT Imaging of Intervertebral Discs Using a Novel Contrast AgentThis study introduces the first use of a contrast agent (potassium iodide) to enhance 3D imaging of the nucleus pulposus within an intact intervertebral disc (IVD). This method was used to demonstrat... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 01/12/2025Karthikeyan Rajagopal & coauthors found that in vivo measurements reveal increased nucleus pulposus lactate and oxygen concentrations in a goat model of intervertebral disc degeneration: onlinelibrary.wiley.... 021
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 01/12/2025Sabina M. Pinto & coauthors present their findings on the relationship between lumbar multifidus morphometry and pain/disability in people with chronic nonspecific low back pain after considering demographics, fear-avoidance beliefs, insomnia, and spinal degenerative changes: onlinelibrary.wiley.... 011
Journal of Orthopaedic Research - Spine® @jorspine.bsky.social · 01/12/2025This review by Kaiyuan Zheng & coauthors emphasizes that macrophage polarization is a pivotal regulator of intervertebral disc degeneration pathology, providing promising therapeutic targets: onlinelibrary.wiley.... 021