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Jonas Köhler

@jonkhler.argmin.xyz
2.9K followers 288 following 135 posts

web @ argmin.xyz interests: machine learning, ai4science, algorithms, coding member of technical staff @ cusp.ai past @ MSR, DeepMind, MPI-IS home @ Heimbach (Gilserberg), Berlin, Europe born @ 353 ppm block toxicity he/him

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Reposted by Jonas Köhler
Michele Invernizzi @invemichele.bsky.social · 09/05/2025
We have a job opening at Peptone.io for an ML researcher. Come help us find new ways to understand and drug intrinsically disordered proteins (IDPs), it's a very interesting and important problem! Link in the reply ↓
Overlayed configurations of a small molecule binding (?) to an unstructured protein
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Jonas Köhler @jonkhler.argmin.xyz · 24/04/2025
Please go ahead!
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Jonas Köhler @jonkhler.argmin.xyz · 19/04/2025
Spending the Easter days prepping for #ICLR2025 in #singapore 😍🤩 If you want to meet/catch up on #CuspAI #AI4Science #MachineLearning and/or ML for #materials / #simulation ping me.! DMs are open :) My lovely colleagues Sina, @sindylowe.bsky.social and Govert are around too!
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Reposted by Jonas Köhler
Guillaume Bellec @bellecguill.bsky.social · 04/01/2025
The blog post of the late Felix Hill is powerful. Stress for AI researchers today is real. I did not know Felix Hill and I am sorry for those who did. This story is perhaps a reminder for students, postdocs, founders and researchers to take care of their well being. medium.com/@felixhill/2...
medium.com
200bn Weights of Responsibility
The Stress of Working in Modern AI
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Jonas Köhler @jonkhler.argmin.xyz · 31/12/2024
Unreal landscapes ❤️
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Jonas Köhler @jonkhler.argmin.xyz · 28/12/2024
github.com/jonkhler/blog/
github.com
GitHub - jonkhler/blog: a personal blog using minimal design principles
a personal blog using minimal design principles. Contribute to jonkhler/blog development by creating an account on GitHub.
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Jonas Köhler @jonkhler.argmin.xyz · 28/12/2024
I think my setup is fine now and quite minimal :) more joking about the universal urge of "maybe I should roll something myself..."
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Jonas Köhler @jonkhler.argmin.xyz · 28/12/2024
🤔🤔
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Jonas Köhler @jonkhler.argmin.xyz · 26/12/2024
@imtd.bsky.social convinced me to turn my homepage into a blog. Not much content yet... Let's see if I stick to it: argmin.xyz.
argmin.xyz
a blog
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Jonas Köhler @jonkhler.argmin.xyz · 25/12/2024
And today, happy Hanukkah 🕎❤️
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Jonas Köhler @jonkhler.argmin.xyz · 25/12/2024
Fun challenge that is apparently hard for LLMs (at least all those I could get my hands on): solving carefully drafted anagrams! New ARC challenge? :D PS: credits go to family Lehmann from Kassel who invent those ridiculously hard Xmas puzzles every year!
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Jonas Köhler @jonkhler.argmin.xyz · 24/12/2024
Merry Christmas! ❤️🌲
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Jonas Köhler @jonkhler.argmin.xyz · 20/12/2024
Actually you convinced me to start one! <3
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Jonas Köhler @jonkhler.argmin.xyz · 20/12/2024
I should... But all the time. Man there are so many things I would love to write a blog about and I never find the time 🫣
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Jonas Köhler @jonkhler.argmin.xyz · 20/12/2024
Segment radixsort, prefixsums and pointwise transforms are just OPed on GPUs. The amount of throughput you can get on a single cheap device is ridiculous! And you can implement so much crazy stuff with just that. ❤️
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Reposted by Jonas Köhler
Bálint Máté @balintmate.bsky.social · 17/12/2024
hello bluesky! we have a new preprint on solvation free energies: tl;dr: We define an interpolating density by its sampling process, and learn the corresponding equilibrium potential with score matching. arxiv.org/abs/2410.15815 with @francois.fleuret.org and @tbereau.bsky.social (1/n)
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Jonas Köhler @jonkhler.argmin.xyz · 13/12/2024
Well, in terms of adding to climate change both are not wrong 🫣
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Jonas Köhler @jonkhler.argmin.xyz · 06/12/2024
You missed adding some GIF :)
media.tenor.com
an ostrich is standing in front of a fence with a horse in the background and a sign that says animal sanctuary
ALT: an ostrich is standing in front of a fence with a horse in the background and a sign that says animal sanctuary
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Jonas Köhler @jonkhler.argmin.xyz · 06/12/2024
Congrats Frank + collaborators! :)
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Jonas Köhler @jonkhler.argmin.xyz · 06/12/2024
Awesome work! Amazing to see this out :)
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Jonas Köhler @jonkhler.argmin.xyz · 02/12/2024
indeed - including less stress/boredom for the audience :D
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Reposted by Jonas Köhler
David Ho @davidho.bsky.social · 25/02/2024
“Sorry”
Underwater photograph of a large whale with a diver in the background, next to an article title that reads "WHAT'S THE FIRST THING WE SHOULD SAY TO THE WHALES?" by Ross Andersen.
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Reposted by Jonas Köhler
Max Schambach @maxschambach.bsky.social · 02/12/2024
I’ll be at NeurIPS next week –happy to connect! Hit me up if you’d like to meet up and chat :) (tabular deep learning; in-context learning; SSL; AI in EU; politics; where to get good coffee/food; your favourite Parks and Rec moment; …)
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Jonas Köhler @jonkhler.argmin.xyz · 02/12/2024
Also regarding this whole insecurity business: one can simply say "good question, honestly I don't know, maybe someone in the audience can help us to clear this up?". I would prefer to hear that a lot more - especially from senior academics - rather than assertive statements.
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Jonas Köhler @jonkhler.argmin.xyz · 02/12/2024
I am personally not at all impressed, intimidated or even excited by a polished business school or flawless but boring diplomat's talk. I personally prefer having one or two memes and puns on the slides so that I don't sleep away rather than boring but correct formal stuff...
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Jonas Köhler @jonkhler.argmin.xyz · 02/12/2024
More on the serious note: my personal advice - especially for many academics - 1. be yourself (=don't act like sb) 2. don't take things too seriously (yes even job talks) 3. don't learn your slides by heart - use them as a visual guide to tell a friend what excites you.
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Jonas Köhler @jonkhler.argmin.xyz · 02/12/2024
This reads like pickup artists giving presentation advice....
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Jonas Köhler @jonkhler.argmin.xyz · 01/12/2024
lets do #rust this year :) #AdventOfCode adventofcode.com/2024/day/1
adventofcode.com
Day 1 - Advent of Code 2024
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Jonas Köhler @jonkhler.argmin.xyz · 01/12/2024
Screenshot of a bluesky profile with "invalid handle" instead of the actual handle.
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Jonas Köhler @jonkhler.argmin.xyz · 01/12/2024
Every two days I get this "invalid handle" label for my custom handle @jonkhler.argmin.xyz (using the DNS TXT config). This seems to be a bug - whenever I reset it, it's fine for another bunch of days. Anyone else experiencing this? If so, what's the cause/fix? #bluesky @jay.bsky.team
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Jonas Köhler @jonkhler.argmin.xyz · 30/11/2024
I guess reformulating the OT problem in a way that you minimize the total action along paths while matching the marginals would give you that.
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Jonas Köhler @jonkhler.argmin.xyz · 30/11/2024
And in the same way OT flow matching showed that there is more in these models than just getting a good marginal (here resulting in faster integration) you could also think about imposing physically amenable states all along the path.
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Jonas Köhler @jonkhler.argmin.xyz · 30/11/2024
That's all a bit hand wavy, but the idea would be: have equilibrium samples in A and B, learn transport maps between them, then study the paths learned to see where and how transitions actually happen.
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Jonas Köhler @jonkhler.argmin.xyz · 30/11/2024
Ah we chatted about applications for predicting trajectories instead of aiming for accurate T=0 images. In this context I remembered that folks looked into DMs to learn physically possible transition paths between two meta stable states using flow matching {...} + u(x) based constraints on paths.
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Reposted by Jonas Köhler
Gabriel Peyré @gabrielpeyre.bsky.social · 30/11/2024
I wrote a summary of the main ingredients of the neat proof by Hugo Lavenant that diffusion models do not generally define optimal transport. github.com/mathematical...
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Jonas Köhler @jonkhler.argmin.xyz · 30/11/2024
I read gossip that LoRa can bring down costs a lot! So maybe not that much? en.m.wikipedia.org/wiki/LoRa
en.m.wikipedia.org
LoRa - Wikipedia
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Reposted by Jonas Köhler
Sander Dieleman @sedielem.bsky.social · 30/11/2024
The link between diffusion models and optimal transport is still a bit of an enigma to me. One thing that's clear: different diffusion models trained on similar datasets tend to recover similar mappings. If these are generally not OT, in what sense are they optimal instead?
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Jonas Köhler @jonkhler.argmin.xyz · 30/11/2024
Oh yeah, that's on my reading list for a while 🫣🫣
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Jonas Köhler @jonkhler.argmin.xyz · 30/11/2024
Something that seems to be in this line of work: arxiv.org/abs/2410.15128
arxiv.org
Generalized Flow Matching for Transition Dynamics Modeling
Simulating transition dynamics between metastable states is a fundamental challenge in dynamical systems and stochastic processes with wide real-world applications in understanding protein folding, ch...
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Jonas Köhler @jonkhler.argmin.xyz · 30/11/2024
More generally: lots of work in ML focuses on the result of the process (final images) and invariance under initialisation seeds. All interesting enough :) But the value of the actual trajectories is underexplored imho. There surely is tons of work already but still seems a bit niche.
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Jonas Köhler @jonkhler.argmin.xyz · 30/11/2024
Dinner table convo from yesterday: if we go from standard diffusion models to flow-matching/Schrödinger bridges and simply try to map two (general) densities onto. What kind of (stochastic) paths do we learn between them? And if it's all physical are those paths too? And if not how to enforce it?
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Jonas Köhler @jonkhler.argmin.xyz · 30/11/2024
Once made use of them for building C\infty smooth flows on compact spaces :) proceedings.neurips.cc/paper_files/...
proceedings.neurips.cc
Smooth Normalizing Flows
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Reposted by Jonas Köhler
François Fleuret @francois.fleuret.org · 29/11/2024
I find strange that engineering the gradient radically to learn better is not a whole field.
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Reposted by Jonas Köhler
Kosta Derpanis @csprofkgd.bsky.social · 28/11/2024
See who has blocked you 🫣 and added you to a list on Bluesky. clearsky.app
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Jonas Köhler @jonkhler.argmin.xyz · 28/11/2024
Yeah and obscure concurrency issues that you did not even think of before 🙄
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Jonas Köhler @jonkhler.argmin.xyz · 28/11/2024
The critical peak is 2021-2022 according to the data. Seems like you have some work to do until Christmas ;)
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Jonas Köhler @jonkhler.argmin.xyz · 28/11/2024
cuda level programming is fun - but also makes me curse a lot :D
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Jonas Köhler @jonkhler.argmin.xyz · 28/11/2024
So better sell all NVIDIA stocks soon? 🤖❄️🧣🧤
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Reposted by Jonas Köhler
Max Schambach @maxschambach.bsky.social · 28/11/2024
I mean, we all know who the only true gold standard for AI publications is, and by that measure it’s not looking good!
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Jonas Köhler @jonkhler.argmin.xyz · 28/11/2024
🙀🙀
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