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Stop and Think

@johnmandrola.skystack.xyz
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A skeptical but not cynical view of scientific evidence This is an automated Substack Account of johnmandrola.substack.com Discover more/Create at: @skystack.xyz

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Stop and Think @johnmandrola.skystack.xyz · 01/07/2026
Body Scanning and Philosophy • The Midjourney promise of body ultrasound, like the total body MRI body imagers, suffer the same problem--and it isn't technical, it's philosophical
johnmandrola.substack.com
Body Scanning and Philosophy
The Midjourney promise of body ultrasound, like the total body MRI body imagers, suffer the same problem--and it isn't technical, it's philosophical
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Stop and Think @johnmandrola.skystack.xyz · 21/06/2026
Just Another Summer Update • Many new powerpoints and my search for fitness
johnmandrola.substack.com
Just Another Summer Update
Many new powerpoints and my search for fitness
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Stop and Think @johnmandrola.skystack.xyz · 18/02/2026
Industry vs Non-Industry Funding for Science • Some thoughts on the role of funding of medical science
johnmandrola.substack.com
Industry vs Non-Industry Funding for Science
Some thoughts on the role of funding of medical science
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Stop and Think @johnmandrola.skystack.xyz · 24/12/2025
Some Year End Things and A Pro-Tip
johnmandrola.substack.com
Some Year End Things and A Pro-Tip
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Stop and Think @johnmandrola.skystack.xyz · 10/12/2025
Do Pictures Change Patient Behaviors? • The Limits of Fear in Medicine
jamesstein18.substack.com
Do Pictures Change Patient Behaviors?
The Limits of Fear in Medicine
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Stop and Think @johnmandrola.skystack.xyz · 26/11/2025
What I believe in Medicine
johnmandrola.substack.com
What I believe in Medicine
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Stop and Think @johnmandrola.skystack.xyz · 16/11/2025
A Fall Update of My Work Outside of the EP Lab
johnmandrola.substack.com
A Fall Update of My Work Outside of the EP Lab
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Stop and Think @johnmandrola.skystack.xyz · 26/10/2025
Medical evidence should not be too technical for doctors
johnmandrola.substack.com
Medical evidence should not be too technical for doctors
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Stop and Think @johnmandrola.skystack.xyz · 30/07/2025
Prasad Being Forced Out of FDA is a Sad Day for Evidence-Based Medicine
johnmandrola.substack.com
Prasad Being Forced Out of FDA is a Sad Day for Evidence-Based Medicine
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Stop and Think @johnmandrola.skystack.xyz · 22/06/2025
This Week in Cardiology Podcast is Fixed • I did a deep dive into cardiac imaging, focusing on the use of CTA for the diagnosis of coronary artery disease. I think the anatomic imaging test is leading us astray.
johnmandrola.substack.com
This Week in Cardiology Podcast is Fixed
I did a deep dive into cardiac imaging, focusing on the use of CTA for the diagnosis of coronary artery disease. I think the anatomic imaging test is leading us astray.
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Stop and Think @johnmandrola.skystack.xyz · 25/05/2025
Restoring Gold Standard Science is Far More than Stopping Fraud • Some brief thoughts on the call for Gold Standard Science
johnmandrola.substack.com
Restoring Gold Standard Science is Far More than Stopping Fraud
Some brief thoughts on the call for Gold Standard Science
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Stop and Think @johnmandrola.skystack.xyz · 11/05/2025
Things I have worked on in the last month
johnmandrola.substack.com
Things I have worked on in the last month
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Stop and Think @johnmandrola.skystack.xyz · 13/04/2025
Trials That Attempt to Expand Treatment Indications but Do Not Increase Knowledge • My latest column is up over at theheart.org | Medscape Cardiology
johnmandrola.substack.com
Trials That Attempt to Expand Treatment Indications but Do Not Increase Knowledge
My latest column is up over at theheart.org | Medscape Cardiology
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Stop and Think @johnmandrola.skystack.xyz · 26/03/2025
Big Weekend Coming Up in Cardiology
johnmandrola.substack.com
Big Weekend Coming Up in Cardiology
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Stop and Think @johnmandrola.skystack.xyz · 02/03/2025
A New Proposal for AF studies: Jettison the "Blanking Period" • Since the beginning of AF ablation 20 years ago, studies have used a 90-day blanking period after the procedure where AF episodes do not count. It is not right.
johnmandrola.substack.com
A New Proposal for AF studies: Jettison the "Blanking Period"
Since the beginning of AF ablation 20 years ago, studies have used a 90-day blanking period after the procedure where AF episodes do not count. It is not right.
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Stop and Think @johnmandrola.skystack.xyz · 29/01/2025
Thoughts on the MAHA Movement
johnmandrola.substack.com
Thoughts on the MAHA Movement
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Stop and Think @johnmandrola.skystack.xyz · 28/11/2024
Thank You
johnmandrola.substack.com
Thank You
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Stop and Think @johnmandrola.skystack.xyz · 19/11/2024
Electrophysiology is on the brink of a possible disaster • A flawed study with positive results has sparked enthusiasm for implantation of left atrial appendage devices during AF ablation. it is a potential disaster.
johnmandrola.substack.com
Electrophysiology is on the brink of a possible disaster
A flawed study with positive results has sparked enthusiasm for implantation of left atrial appendage devices during AF ablation. it is a potential disaster.
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Stop and Think @johnmandrola.skystack.xyz · 02/10/2024
Links to My Recent Writing and Speaking • I have been busy writing. Here is a summary and links.
johnmandrola.substack.com
Links to My Recent Writing and Speaking
I have been busy writing. Here is a summary and links.
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Stop and Think @johnmandrola.skystack.xyz · 22/09/2024
I Might Have Been Wrong About Pulsed Field Ablation for Atrial Fibrillation • Emphasis on "might"
johnmandrola.substack.com
I Might Have Been Wrong About Pulsed Field Ablation for Atrial Fibrillation
Emphasis on "might"
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Stop and Think @johnmandrola.skystack.xyz · 28/08/2024
How do Dubious Norms Get Established? • A look at an old trial might explain how the norms of cardiology came to be despite a dubious evidence base
johnmandrola.substack.com
How do Dubious Norms Get Established?
A look at an old trial might explain how the norms of cardiology came to be despite a dubious evidence base
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Stop and Think @johnmandrola.skystack.xyz · 17/07/2024
The Cardiology Seminal Trial's series is well underway • Please do read the seminal trials. You will learn stuff that you likely did not know. Stuff that does not make the colored boxes in guidelines.
johnmandrola.substack.com
The Cardiology Seminal Trial's series is well underway
Please do read the seminal trials. You will learn stuff that you likely did not know. Stuff that does not make the colored boxes in guidelines.
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