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Joana Catarino

@joanafacatarino.bsky.social
59 followers 163 following 1 posts

PhD student in Systems Neuroscience at Karolinska Institutet | Carlén lab 🧠🐀 PFC, Striatum, Cognitive flexibility and ASD

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Reposted by Joana Catarino
Knut and Alice Wallenberg Foundation @kawresearch.bsky.social · 22/01/2026
For more than a century anatomical maps divide the #brain into regions according to structural variations in the tissue. But do these divisions really reflect how the brain works? A new study on mice from @ki.se suggests that this is often not the case #research #neuroscience tinyurl.com/4jtffpc2
tinyurl.com
New brain maps challenge traditional descriptions of the brain
For more than a century, maps of the brain have been based on how brain tissue looks under the microscope. These anatomical maps divide the brain into regions according to structural variations in the...
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Reposted by Joana Catarino
International Brain Laboratory @intlbrainlab.bsky.social · 03/09/2025
Two flagship papers from the International Brain Laboratory, now out in ‪@Nature.com‬: 🧠 Brain-wide map of neural activity during complex behaviour: doi.org/10.1038/s41586-025-09235-0 🧠 Brain-wide representations of prior information in mouse decision-making: doi.org/10.1038/s41586-025-09226-1 +
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Reposted by Joana Catarino
Guido Meijer @guidomeijer.com · 05/08/2025
🚨Pre-print alert🚨 We stimulated serotonin with optogenetics while doing large-scale Neuropixel recordings across the mouse brain. We found strong widespread modulation of neural activity, but no effect on the choices of the mouse 🐭 How is this possible? Strap in! (1/9) 👇🧵 doi.org/10.1101/2025...
doi.org
Serotonin drives choice-independent reconfiguration of distributed neural activity
Serotonin (5-HT) is a central neuromodulator which is implicated in, amongst other functions, cognitive flexibility. 5-HT is released from the dorsal raphe nucleus (DRN) throughout nearly the entire f...
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Joana Catarino @joanafacatarino.bsky.social · 24/02/2025
Come join us at KI and help understanding the role of the PFC-Striatum pathway in cognitive flexibility 🧠 Great science, amazing team and in a beautiful city!
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Reposted by Joana Catarino
Matteo Carandini @carandinilab.net · 07/02/2025
Neuropixels and Optogenetics are delighted to announce the birth of Neuropixels Opto Combining high-resolution electrophysiology and optogenetics Today in bioRxiv 960 sites, 28 emitters, 2 colors By Lakunina, @karolinazsocha.bsky.social, Ladd, et al www.biorxiv.org/content/10.1... (1/2)
A Neuropixels Opto probe with 3 blue emitters and 3 red emitters lighting up in succession, with corresponding neural activity in different layers of the cortex.
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Reposted by Joana Catarino
Pierre Le Merre @pierrelemerre.bsky.social · 25/11/2024
Our new study is out on BioRXiv! tinyurl.com/pfcmap We (@carlenlab.bsky.social lab) mapped the mouse PFC using single-unit activity! We recorded ~23,000 neurons across cortical/subcortical regions and profiled spont. firing patterns to reveal what separates the PFC from other brain regions. 1/n
biorxiv.org
A Prefrontal Cortex Map based on Single Neuron Activity
The intrinsic organization underlying the central cognitive role of the prefrontal cortex (PFC) is poorly understood. The work to date has been dominated by cytoarchitecture as a canvas for studies on...
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