3/ We built a landing pad platform to introduce ~18,000 cDNA variants into a safe harbor locus of hiPSCs, then differentiated them into cardiomyocytes and epicardial progenitor cells to assay how cardiac cells handle mutated lamin proteins.
Jessica Mella
@jmella.bsky.social
211 followers 423 following 5 posts
PhD student studying nuclear lamin structure/function in the Buchwalter lab @UCSF. Fan of cell type-specific bio, all things proteostasis, and Karl the Fog.