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Toxicology Policy Research Team

@jhutoxteam.bsky.social
29 followers 13 following 210 posts

A non-partisan team bringing 21st century science into regulatory decision making. Better outcomes, fewer animals, stronger public health.

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Toxicology Policy Research Team @jhutoxteam.bsky.social · 09/10/2026
In today’s spotlight, we’re looking at an article by IEEE discussing lung organoids and the current difficulties of facilitating widespread NAMs adoption. Read the article at spectrum.ieee.org/alternatives... What are your thoughts on the article? Let us know
spectrum.ieee.org
Can New Technologies Finally Replace Animal Testing?
Changing habits may be the hardest engineering challenge of all
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 01/10/2026
New ToxBlog by Yiguang Zhu: "What is ICCVAM for, anymore?" Read the blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What are your thoughts on this weeks blog? Let us know in the comments
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 17/09/2026
New ToxBlog by Vesna Adjei: Release the Rabbits: What Two Decades of EU Skin Irritation Testing Trends Reveal About Replacing Animal Models Read the blog post here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What your thoughts on the blog? Let us know in the comments
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 11/09/2026
In this new spotlight, we’re looking at an article from Open Access Government discussing the STEP4NAMs project and how it aims to guild Europe’s capacity for wide spread adoption of New Approach Methodologies Read the article here: www.openaccessgovernment.org/article/buil...
openaccessgovernment.org
Building Europe’s capacity for new approach methodologies
The STEP4NAMs project aims to overcome barriers to the adoption of New Approach Methodologies (NAMs) in Europe’s biomedical research
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 04/09/2026
New ToxBlog by Anicca Harriot: Snails, Snakes, and Sourcing Novel Compounds for Drug Development Read the article here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What are your thoughts on the article? Let us know in the comments.
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 03/09/2026
Today's ToxBlog will be going out a bit later then usual. We thank you for your patience
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 28/08/2026
In today’s spotlight, we’re looking at an article from Nature discussing NAMs, the current hurdles that prevent widespread NAMs implementation, and the promising development of “digital twins” Read the article here: www.nature.com/articles/s41...
nature.com
Advancing FDA New Approach Methodologies from animal models through digital twins - npj Digital Medicine
npj Digital Medicine - Advancing FDA New Approach Methodologies from animal models through digital twins
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 20/08/2026
New Guest Toxblog by Kinga Nimz, Karolina Jagiello, PhD and Maciej Stępnik, MD, PhD, DSc: Professional Perspectives: How Online NAM Platforms Are Changing Toxicity Testing Read the blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What are your thoughts on the blog? Let us know.
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 14/08/2026
In today’s spotlight, we’re looking at an article from RTI International discussing NAMs. Read the full article at www.rti.org/insights/new... What are your thoughts on the article? Let us know in the comments
rti.org
New Approach Methodologies: Why Scientific Rigor Matters More Than Ever
NAMs and advanced in vitro models are transforming chemical safety assessment, but scientific rigor remains essential for regulatory confidence. Learn more.
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 06/08/2026
New ToxBlog by Mackensey Alexander: How Legal Liability Concern is Slowing the Future of NAMs Read the article: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What are your thoughts on this weeks blog. Let us know
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 31/07/2026
In today’s spotlight we’re looking at an article from the NAMs Journal discussing the necessity of single, unified definition for New Approach Methodologies. Read the article here: www.sciencedirect.com/science/arti... What are your thoughts the topic of NAMs definitions?
sciencedirect.com
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 23/07/2026
New ToxBlog by Shannon Dixon: Green Chemistry - The Prevention of Waste at the Source Read the full blog post here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What are your thoughts on the blog? Let us know in the comments
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 17/07/2026
In today’s spotlight, we’re looking at article from the Baltimore Banner remembering the life of Hopkins Professor Alan M. Goldberg. What are your thoughts on Dr. Goldberg’s legacy? Let us know in the comments Read the article here: www.thebanner.com/obituaries/a...
thebanner.com
The longtime Hopkins professor who fought for animal testing alternatives
Alan Goldberg, the founder of the Center for Alternatives to Animal Testing at Johns Hopkins University, died June 9 of pneumonia. He was 86.
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 09/07/2026
New ToxBlog by Zachary Liebowitz: The Replacement Trap: NAMs Are Built for Integration not One-for-One Animal Replacement Read the blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What are your thoughts on the blog? Let us know in the comments
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 01/07/2026
For today’s organization spotlight, we’re focusing on the Physicians Committee for Responsible Medicine (PCRM).
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 25/06/2026
Dr. Paul Locke was recently quoted in a viewpoints article by the Johns Hopkins Center for A Livable Future discussing the current state of animal rights in the United States. Read the article: clf.jhsph.edu/viewpoints/a... What are your thoughts on the article? Let us know
clf.jhsph.edu
Attorney and Scientist Paul Locke: Can We Respect Animals?
Professor Paul Locke believes that when it comes to how we treat animals, especially food animals, we have a cognitive dissonance problem.
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 25/06/2026
New ToxBlog by Mariah Bowman: Reaching the goals of the AWA and HREA by reconsidering IACUC members and their roles Read the blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What are you thoughts on the article? Let us know in the comments.
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 19/06/2026
In today’s spotlight, we’re looking at an article from Cruelty Free International our workshop Examining the Second Species Requirement in ICH M3 back in May. Read the article here: www.crueltyfreeinternational.org/is-the-tide-... Let us know your thoughts.
crueltyfreeinternational.org
Is the tide turning on second species testing? - Cruelty Free International
We brought together international experts on second species testing in drug development in a landmark workshop.
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 11/06/2026
New ToxBlog by Akosua Dufie: More than a Guideline: Why Compliance with the PHS Policy is not Optional Link to the article here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What are your thoughts on the ToxBlog? Let us know in the comments below
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 05/06/2026
For Today’s Friday spotlight, we’re looking at an literature review from frontiers discussing the current state of New Approach Methods and how they can be integrated into next-generation risk assessment. Link to article here: www.frontiersin.org/journals/tox...
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 03/06/2026
(1/3) For today’s organization spotlight we’re looking at the 3Rs Collective (3RsC) As an organization, 3RsC’s goal is to spearhead initiatives to advance the 3Rs: refinement, reduction, replacement.
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 28/05/2026
New ToxBlog by Loza Taye: What’s Next for the Second Species? Read the full blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... Were you at the second species workshop? Let us know in the comments below
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 22/05/2026
Several members of ToxTeam will be presenting their work at this year’s MPS World Summit. The MPS World Summit is the annual meeting that brings together leaders in the field to discuss advancements of MPS and organ on chip technologies. Stay tuned for updates Learn more here : mpsworldsummit.org
mpsworldsummit.org
Home - MPS World Summit
First Microphysiological Systems World Summit. Explore the details on presenters, registration and in person or on-line participation.
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 21/05/2026
New Guest ToxBlog by Emily Zweig: Refinement of Animal Toxicology Research Techniques: Ethical and Scientific Advantages of Microsampling Read the Blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What are your thoughts on the article? Let us know in the comments below
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 19/05/2026
Today is the last day to register for the “Examining the Second Species Requirement in ICH M3” workshop. Register using the link here: www.jhutoxicologypolicyresearch.org/events/secon...
jhutoxicologypolicyresearch.org
Examining The Second Species Requirement in ICH M3 — JHU Toxicology Policy Lab
Regulatory agencies typically require toxicity testing in both a rodent and a non-rodent species before new drugs can proceed to human trials. Given rapid advancements in human-relevant science, what ...
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 15/05/2026
In today’s spolight we’re focusing on an editorial from Frontiers talking about new approach methods being used for the toxicological assessment of tobacco and nicotine products. What are your thoughts on the article? Read the article here: www.frontiersin.org/journals/tox...
frontiersin.org
Frontiers | Editorial: Application of new approach methodologies in toxicological assessment of next-generation tobacco and nicotine products
traditional animal testing to new approach methodologies (NAMs), aiming to reduce, refine, or replace (known as the "3R") animal-based methods typi...
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 13/05/2026
(1/4) For today’s organization spotlight, we’re focusing on the Johns Hopkins Center for Alternatives to Animal Testing (CAAT).
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 11/05/2026
Reminder that we will be working in collaboration with Cruelty Free international to host a workshop at The Bloomberg Center on May 21st and 22nd. Use the link or the QR code below for more information. www.jhutoxicologypolicyresearch.org/events/secon...
jhutoxicologypolicyresearch.org
Examining The Second Species Requirement in ICH M3 — JHU Toxicology Policy Lab
Regulatory agencies typically require toxicity testing in both a rodent and a non-rodent species before new drugs can proceed to human trials. Given rapid advancements in human-relevant science, what ...
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 07/05/2026
We're 2 weeks out from the workshop we're hosting in collaboration with Cruelty Free International examining the second species requirement in ICH M3. In anticipation for the event, we're releasing an agenda that you can read below. Learn more about the event here: buff.ly/7WJcgrM
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 07/05/2026
New Toxblog by Jorge Gana: NAMs in Industry: FDA Shows Emerging Trends in Regulatory Submissions Read the article: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What are your thoughts on the article? Let us know in comments below
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 06/05/2026
Join us May 21-22, 2026, for a timely, science-driven discussion on the regulatory and evidentiary foundations of the two-species requirement in ICH M3. For more details about the event and registration, follow the link here: www.jhutoxicologypolicyresearch.org/events/secon...
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 01/05/2026
In today’s spotlight, we’re looking at an article from the Texas Biomedical Research Institute discussing how the Southwest National Primate Research Center works to develop NAMs. Read the article here: www.txbiomed.org/news-press/n... What are your thoughts on the article?
txbiomed.org
Texas Biomed and SNPRC advancing new approach methodologies (NAMs) - Texas Biomed
(March 12, 2026) -- Texas Biomedical Research Institute is studying and innovating new tools – known as new approach methodologies (NAMs) – that can
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 23/04/2026
New Guest ToxBlog by Anjali Kumar: Professional Perspectives: Innovation Without Cruelty: Replacing Animals with Artificial Intelligence Read the full blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What are your thoughts on the use artificial intelligence to replace animal models?
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 21/04/2026
Reminder that we’re one month away from workshop “Examining The Second Species Requirement in ICH M3” done in collaboration with Cruelty Free international. For more information, use QR code below or the link here: www.jhutoxicologypolicyresearch.org/events/secon...
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 20/04/2026
Reminder that The Career Connection event hosted by the Johns Hopkins Lerner Center for Public Health Advocacy Center is happening tomorrow, April 21st from 12:00 to 1:15 PM. Learn more at the link here: publichealth.jhu.edu/lerner-cente...
publichealth.jhu.edu
The Career Connection | Johns Hopkins Lerner Center for Public Health Advocacy
The Career Connection is a networking opportunity for aspiring public health advocacy professionals at the Bloomberg School to hear insights and gain knowledgeable information from leaders in the…
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 17/04/2026
In today's spotlight, we're looking at an article discussing the tissue chips the flew along side the crew of the Artemis II earlier this year. What are your thoughts the article? let us know in the comments. Link to the article: science.nasa.gov/directorates...
science.nasa.gov
Avatars for Astronaut Health to Fly on NASA’s Artemis II - NASA Science
The AVATAR (A Virtual Astronaut Tissue Analog Response) investigation will use organ-on-a-chip devices, or organ chips, to study the effects of deep space radiation and microgravity on human health.…
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Reposted by Toxicology Policy Research Team
Lerner Center for Public Health Advocacy @jhadvocacy.bsky.social · 13/04/2026
What to expect from our Career Connection event on April 2: 🌷Insightful lightning talks from several “career guides” 🌷The opportunity to engage and connect with speakers and other attendees 🌷Lunch! Learn more & RSVP: lerner.center/4boViql
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 10/04/2026
(1/5) In all the excitement surrounding Artemis II, some might have overlooked the work being done for the AVATAR investigation.
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 09/04/2026
New Guest Toxblog by Vinita Chauhan: Professional Perspectives: Adverse Outcome Pathways to Contextualize Mechanistic Data for Chemical and Radiation Research Read the blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo...
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 07/04/2026
Reminder that The Career Connection event hosted by the Johns Hopkins Lerner Center for Public Health Advocacy Center will happen on April 21st from 12:00 to 1:15 PM. Learn more at the link here: publichealth.jhu.edu/lerner-cente...
publichealth.jhu.edu
The Career Connection | Johns Hopkins Lerner Center for Public Health Advocacy
The Career Connection is a networking opportunity for aspiring public health advocacy professionals at the Bloomberg School to hear insights and gain knowledgeable information from leaders in the…
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 03/04/2026
(1/2) In Today’s spotlight we’re looking at an article from MSUToday discussing the news about the two Michigan State University Professors, Kevin C. Elliot and John C. What are your thoughts on New Approach Methodologies Decision Center? Let us know in the comments
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 26/03/2026
New ToxBlog by CriShaun Hardy: Xenotransplantation and the Future of Organ Supply: A Case for Human-Derived Alternatives Read the full blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What are your thoughts on xenotransplantation? Leave a comment below
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 23/03/2026
We’re happy to announce that Lena Smirnova and Erik Johnson was given an award by NIH to develop a NAMs platform to test potential new treatments for neurological diseases. Congrats to Lena and Erik on the award. Read the full coverage here: publichealth.jhu.edu/2026/johns-h...
publichealth.jhu.edu
Johns Hopkins Researchers Awarded $15 Million to Develop Platform to Study Neurological Diseases and Screen Chemicals Using ‘New Approach Methodologies’ | Johns Hopkins Bloomberg School of Public Health
Researchers will join new NIH-supported network working to develop new approach methodologies that complement or replace animal testing.
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 20/03/2026
For today’s spotlight, we’re looking at statement from the FDA about the recently released draft guidance on alternatives to animal testing in drug development. Read the statement here: www.fda.gov/news-events/... What are your thoughts on the statement or the new guidance?
fda.gov
FDA Releases Draft Guidance on Alternatives to Animal Testing in Drug Development
The U.S. Food and Drug Administration today issued draft guidance intended to help drug developers validate new approach methodologies (NAMs) to be used instead of animal testing in drug development,…
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 17/03/2026
Dr. Paul Locke will be speaking at a virtual webinar hosted by Radboud University on March 19 & 20th discussing some of the hurdles preventing the further adoption of New Approach Methodologies (NAMs) in biomedical research. Register at the link here: tinyurl.com/nam-workshop
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 12/03/2026
New ToxBlog by Aaradhya Diwan: Our Tiny Allies in Toxicological Testing Part 3 – Small Flowering Plants as Alternative Models Read the Blog here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What do you think about using flowering plants as NAMs Let us know in the comments below.
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 06/03/2026
For today’s spotlight we’re looking at a podcast by BioSpace that featured CAAT director Thomas Hartung talking about drug discovery and development will be improved though technology such as Artificial Intelligence and Organoids. Link to podcast: www.biospace.com/drug-develop...
biospace.com
As FDA Moves Away From Animal Testing, AI and Organoids Can Shine
Johns Hopkins’ Thomas Hartung discusses how drug discovery and development will change under evolving regulatory policies that embrace AI technology as well as organoid and other non-animal models of…
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 26/02/2026
New ToxBlog by Mariah Bowman: The Production of Antivenom and Implementing the 3Rs Read the full blog Post here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What are your thoughts on toxicovenomics? Let us know on the comments
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 20/02/2026
For today’s spotlight, we’re looking at an article from the Lancet discussing efforts in both the US and UK to move away from animal testing using New Approach Methods. What are your thoughts on these efforts? Link in the articles: www.thelancet.com/journals/lan...
thelancet.com
The end of animal testing?
Both the UK and US Governments have pledged to end research using animals, but is such a goal realistic? And how might it change medical research? Talha Burki reports.
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Toxicology Policy Research Team @jhutoxteam.bsky.social · 12/02/2026
New Blog by Blair Eagleson: SEC v. Jarkesy: What Does It Mean for Laboratory Animals? Read the article here: www.jhutoxicologypolicyresearch.org/tox-blog/blo... What are your thoughts on the case? Let us know in the comments
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