Jeff Miner @jeffminerphd.bsky.social · 21/03/2026Hallelujah! How about you, Delta and American and Southwest???? 010
Jeff Miner @jeffminerphd.bsky.social · 26/02/2026The defects in the Alport GBM allow plasma proteins to penetrate and become lodged or integrated, and they may interact with cellular receptors. Our data suggest that some of the mesangial matrix proteins in healthy mice come from the blood as well. 131
Jeff Miner @jeffminerphd.bsky.social · 26/02/2026Glomerular basement membrane (GBM) structural integrity dictates trans-tissu... www.sciencedirect.com/science/arti... Really proud of this Cell Reports paper showing that the potentially pathogenic laminin alpha2 in the Alport GBM comes not from glomerular cells, but from the bloodstream.sciencedirect.comGlomerular basement membrane structural integrity dictates trans-tissue deposition of laminin in the kidneyBasement membranes (BMs) are specialized extracellular matrices (ECMs) essential for tissue structure and function. In non-vertebrates, ECM components… 1109
Jeff Miner @jeffminerphd.bsky.social · 14/11/2025Great collaboration! So happy that our O'Brien Kidney Center Variant Validation Core could help out with the VUS analyses. @washunephrology.bsky.social @obrienkidney.bsky.social 082
Jeff Miner @jeffminerphd.bsky.social · 11/11/2025Your ASN-AHA Young Investigator Award seems like yesterday! Congratulations on the 2-peat! 030
Jeff Miner @jeffminerphd.bsky.social · 10/11/2025This makes me very curious about the COL4A5 variant! 160
Reposted by Jeff MinerMichelle Rheault, MD @rheaultm.bsky.social · 06/11/2025Highlights from my talk yesterday on Alport syndrome spectrum of disorders. (since no one posted it, I'll have to do it myself) Variants in type IV collagen cause a wide spectrum of disease. #KidneyWk 🧵 35022
Jeff Miner @jeffminerphd.bsky.social · 06/11/2025Thanks to Julie Inglefinger for this enlightening summary at ASN KidneyCure Week! 010
Jeff Miner @jeffminerphd.bsky.social · 04/11/2025Spreading the word about the Importance and Power of Podocytes at @asnkidney.bsky.social Kidney Week in Houston. @isgd.bsky.social 091
Jeff Miner @jeffminerphd.bsky.social · 04/11/2025Thanks to NIDDK for funding this work! #AlportSyndrome @alportuk.bsky.social @alportalliance.bsky.social 030
Jeff Miner @jeffminerphd.bsky.social · 04/11/2025I first presented the data in this paper at the Philly Podocyte meeting in May 2023 (thanks @ksusztak.bsky.social & Larry Holzman), and a few days ago the paper appeared in @kidneyint.bsky.social . Promising results for new ways to treat Alport syndrome. kidney-international.org/article/S008...kidney-international.orgMouse Alport podocytes are susceptible to AAV9 transduction in vivoAlport syndrome features a defective glomerular basement membrane (GBM) due to variants in COL4A3, COL4A4, and COL4A5. The most severe forms, which lack the GBM’s collagen α3α4α5(IV) network, progress... 053
Jeff Miner @jeffminerphd.bsky.social · 06/10/2025Structurally beautiful--and beautifully functional, too! 140
Reposted by Jeff MinerASNKidney @asnkidney.bsky.social · 22/09/2025📢 Ready to take your research further? The 2026 KidneyCure Grant cycle is open. Funding, mentorship, and resources are waiting. Applications close on Thursday, November 20, at 2:00 p.m. EST. Programs support fellows, PhD students, and early-career faculty in kidney care: bit.ly/kcgrantsfund... 021
Jeff Miner @jeffminerphd.bsky.social · 24/08/2025Congratulations Stephen! I look forward to hearing your talk in Baltimore in November at ASMB 2025! @amsocmatbio.bsky.social 030
Jeff Miner @jeffminerphd.bsky.social · 24/08/2025This reminds me of early days of email & listservs & out of office autoreplies. Someone on a listserv would have auto replies turned on but no limit of once per address. This caused an endless loop of autoreplies to the listserv, received by all. People replied "take me off" & the cycle continued. 130
Reposted by Jeff MinerASNKidney @asnkidney.bsky.social · 19/08/2025🚨 Final call: The ASN Loan Mitigation Program closes tomorrow, Wednesday, August 20, at 2:00 p.m. EDT. Get your application in for a chance at $50K over three years toward student loans to reduce your debt and focus on your career in kidney care. 👉 bit.ly/lmp2025 001
Reposted by Jeff MinerArnold D. @kidneyrebel.bsky.social · 09/08/2025Very happy that Kidney News published my call for a kidney care revolution. Thank you to @asnpublications and everyone who has guided me along the way. 162
Jeff Miner @jeffminerphd.bsky.social · 01/08/2025Check out my article on Alport syndrome in the July ASN Kidney News: "From Basement Membrane Thinning to Alport Syndrome: An Array of Presentations Caused by COL4A3/A4/A5 Gene Variants" www.kidneynews.org/view/journal...kidneynews.org 021
Reposted by Jeff MinerASNKidney @asnkidney.bsky.social · 31/07/2025🗳️ Voting for the ASN Council Election is now open! Select the next Executive Councilor and At-Large Councilor. Your voice helps shape what’s next in kidney care. Deadline: Friday, September 5, at 11:59 p.m. EDT 🔗https://www.asn-online.org/vote 011
Jeff Miner @jeffminerphd.bsky.social · 31/07/2025Thrilled to have this finally published! If you are interested in learning about the collagen IV diseases Gould syndrome and Alport syndrome, add this to your reading list. www.nature.com/articles/s41...nature.comCollagen IV in Gould syndrome and Alport syndromeNature Reviews Nephrology - In this Review, the authors focus on the role of collagen IV in Gould syndrome and Alport syndrome. They discuss the molecular and phenotypic similarities and... 53110
Reposted by Jeff MinerInternational Society of Glomerular Disease @isgd.bsky.social · 11/06/2025Joshua's story about living with APOL1-associated diasease inspired Dr. Katalin Susztak to present the connecting bridges from mapping to mechanisms to medicine! 💊 More results at the next #PodocyteConference? 🤩 051
Reposted by Jeff MinerArdem Patapoutian @ardemp.bskyverified.social · 03/06/2025Talked to @KateZernike at @nytimes about my journey and the current moment for scientists in the U.S. “Ardem Patapoutian’s story is not just the American dream, it is the dream of American science.” Read the article here. No subscription required: www.nytimes.com/2025/06/03/u...nytimes.comThe U.S. Lit a Beacon for Science. Under Trump, Scientists Fear It’s Dimming 722893
Jeff Miner @jeffminerphd.bsky.social · 11/05/2025Just attended a terrific meeting on Alport Syndrome So many talented experts in the room + the most involved patients. And so much hope for progress towards new treatments. 020
Reposted by Jeff MinerO'Brien Kidney Resource Alliance (OKRA) @obrienkidney.bsky.social · 02/04/2025The OKRA National Forum is happening tomorrow from 12-1pm CST / 1-2pm EST! Dr. Naoka Murakami (WashU) will be discussing “T cells in Kidney Wells: Lessons from Immunotherapy-associated Kidney Injury.” Learn more and register at our website: www.uab.edu/okra/trainin... 021
Jeff Miner @jeffminerphd.bsky.social · 30/03/2025The Verdict is great. Paul Newman vs. Hospital Doctors. 020
Jeff Miner @jeffminerphd.bsky.social · 25/03/2025A bright spot regarding NIH: A colleague whose R01 scored 5% in July 2024, with an expected September 2024 start date, finally received the Notice of Award today, with only a standard administrative budget cut. The wheels really are turning. 020
Reposted by Jeff MinerASMB @amsocmatbio.bsky.social · 25/03/2025#JOIN us #TOMORROW for an exciting e-symposium exploring the critical role of the #ECM in #womensHealth Register⏩http://asmb.net/e-symposia #ECMatrixIsEverywhere #WomensHealth #MeetTheOrganizers: Dr. Pilar de la Puente (@delapuente_lab) & Dr. Maria Gonzalez Porras (@GonzalezPLab) 065
Reposted by Jeff MinerPrabir Roy-Chaudhury @roy-chaudhury.bsky.social · 23/03/2025A great collection of people and passion at the @asnkidney.bsky.social @ahascience.bsky.social Saving Kidneys Hearts and Lives workshop 051
Reposted by Jeff MinerRachel Lennon @rachellennon.bsky.social · 20/03/2025Having a fabulous Bluesky day in Japan! Trip to Minamata with team #Alport & family @moumitabarua.bsky.social @jeffminerphd.bsky.social @alportuk.bsky.social 0164
Jeff Miner @jeffminerphd.bsky.social · 18/03/2025It’s always a special evening when having a yakitori dinner with former Japanese postdocs in Tokyo. @washunephrology.bsky.social 0131
Reposted by Jeff MinerASN Publications @asnpublications.bsky.social · 12/02/2025Alport syndrome is an inherited disorder characterized by kidney disease, sensorineural hearing loss, and ocular abnormalities. In this review, the authors provide an overview of how genotype-phenotype-mechanisms are key for a precision medicine-based approach in the future. bit.ly/JASN0647 #ASNJASN 031
Jeff Miner @jeffminerphd.bsky.social · 12/02/2025Greetings from thankfully in-progress DDK-G study section, reviewing KUH Fellowship grants. Such dedicated reviewers, especially one who joins us from Hawaii, where it is 2 am. 031
Reposted by Jeff MinerASMB @amsocmatbio.bsky.social · 11/02/2025🎉Today we celebrate International Day of Women and Girls in Science! We are extremely #PROUD of all the #WomenInASMB, their accomplishments, both past and present, and we are excited to see what the future holds! #WomenInSTEM #ECMatrixIsEverywhere #ScienceNoBoundaries 0194
Jeff Miner @jeffminerphd.bsky.social · 10/02/2025Failure to award these grants for upcoming scientific conferences could be devastating for small societies and long-running research conferences (e.g., Gordon) that depend on this funding to support the exchange of ideas, networking, and exposure for junior scientists trying to build their careers. 000
Jeff Miner @jeffminerphd.bsky.social · 10/02/2025What about R13 grants in any stage of review? They should all have a mandatory Diversity Plan included. And what about new R13 grants in preparation for the April deadline--should the Diversity Plan be left out, or are new submission guidelines expected? 100
Jeff Miner @jeffminerphd.bsky.social · 07/02/2025You'll be hearing from me on one of these dates. More to come! @washunephrology.bsky.social 040
Jeff Miner @jeffminerphd.bsky.social · 05/02/2025Regarding my February NIH Study Section meeting, I received this email overnight: Dear Dr. Miner, Our meeting will be held on Feb. 12 as planned. I am grateful for the lack of uncertainty, as my reviews are due shortly after the Super Bowl ends. My fingers are crossed. 0140
Jeff Miner @jeffminerphd.bsky.social · 04/02/2025Any anecdotal info on NIH Study Section meetings this week? 000