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Joe Bondy-Denomy

@jbdsf.bsky.social
281 followers 123 following 19 posts
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Joe Bondy-Denomy @jbdsf.bsky.social · 24/04/2026
Phage community: our plasmids for executing phage transposon mutagenesis are now on AddGene and I would love for you to try it out! It is powerful for ID'ing all essential genes and knocking out all non-essentials in a single experiment :) New exp here: www.addgene.org/browse/artic...
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Joe Bondy-Denomy @jbdsf.bsky.social · 08/12/2025
Phages are full of genes of unknown function that are likely adaptive in specific conditions. New preprint: Phage TnSeq identifies essential genes rapidly and knocks all non-essentials. We would like to send a pool of phiKZ mutants to anyone wanting it! Reach out tinyurl.com/bdcfrejh
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Joe Bondy-Denomy @jbdsf.bsky.social · 03/04/2025
Interested in phage defenses that natively block lytic phage used in therapies? Or do you want to figure out if a phage has a modified genome? Meet the END-nucleases, an enzyme family that can broadly restrict phages with many diverse modifications. From talented post-doc Wearn-Xin Yee!
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