iiinova — where your digital self keeps evolving

Reposted by Jaime Manzano

Javier Padilla @javierpadillab.bsky.social · 04/09/2026

Muy buen artículo de @jaimemanzano.bsky.social sobre inversión pública en I+D, lo que pasa y lo que tendría que pasar para garantizar que redundara en una mejora en el acceso a aquello que se ha construido con un papel de lo público. elpais.com/planeta-futu...

elpais.com

Por qué los medicamentos financiados con dinero público siguen siendo inaccesibles para millones de personas

Europa decidirá en los próximos meses si quienes reciben financiación pública para investigar nuevos medicamentos deben asumir compromisos para facilitar su acceso

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Reposted by Jaime Manzano

Drugs for Neglected Diseases initiative (DNDi) @dndi.org · 03/09/2026

Join us for a discussion on the growing practice of Access Planning in R&D, examining how it can help ensure that publicly funded R&D translates into timely public health-driven innovation and accessible, affordable, and available resulting health technologies. docs.google.com/forms/d/e/1F...

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Jaime Manzano @jaimemanzano.bsky.social · 01/09/2026

WHO-prequalified generics have substantially improved availability in many low- and middle-income countries. In the EU/EEA, however, no currently available rifapentine formulation has EMA approval, leaving countries dependent on exceptional importation or special-access mechanisms. Full article:

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Jaime Manzano @jaimemanzano.bsky.social · 26/08/2026

The result was rifampicin. Its introduction helped transform TB treatment from a therapy lasting around 18 months towards the much shorter regimens that followed. And a nice detail: the rifamycins were named after Rififi, the French crime film the researchers liked. /3

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Jaime Manzano @jaimemanzano.bsky.social · 26/08/2026

...a soil sample collected in a pine forest near Saint-Raphaël, France. At Lepetit laboratories in Milan, Sensi and colleagues isolated the microorganisms producing rifamycins and then screened hundreds of semi-synthetic derivatives. /2

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Jaime Manzano @jaimemanzano.bsky.social · 26/08/2026

Born #OnThisDay in 1920, Italian chemist Piero Sensi led the team behind one of the breakthroughs that transformed tuberculosis treatment. #TBsky It started with...🧵

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Jaime Manzano @jaimemanzano.bsky.social · 25/08/2026

TB thus appears on both sides of Francoist Spain’s diplomatic transformation, providing a lens through which to see Spain changing the international system to which it sought to belong.

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Jaime Manzano @jaimemanzano.bsky.social · 25/08/2026

On 28 May 1951, Spain joined WHO. And TB followed Spain into this new international order. In 1952, WHO sent a TB consultant to assess the situation in Spain. WHO and Spain ultimately decided not to establish a specific TB programme, prioritising other areas.

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Jaime Manzano @jaimemanzano.bsky.social · 25/08/2026

Then came a remarkable continuity. The same José Alberto Palanca who had represented Spanish public health in the Axis health networks was involved in Spain’s return to multilateral health cooperation.

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Jaime Manzano @jaimemanzano.bsky.social · 25/08/2026

By 1950–51, Francoist Spain was looking elsewhere. The UN reversed its diplomatic boycott in 1950 and, in 1951, Spanish TB expert Benítez Franco received the Medal of Honour of the French Committee against Tuberculosis. This is a recognition to Spain’s changing relations with Western democracies.

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Jaime Manzano @jaimemanzano.bsky.social · 25/08/2026

In 1941, Spain’s Director-General of Health, José Alberto Palanca, travelled through Germany and Italy. In Berlin, he attended an international TB conference intended to establish a new international anti-tuberculosis organisation within the Nazi “New Europe”.

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Jaime Manzano @jaimemanzano.bsky.social · 25/08/2026

Tuberculosis offers a fascinating window into Francoist Spain’s changing place in the world. In the 1940s, TB connected Spanish public health to the international networks of the Axis. A decade later, it reappeared as Spain entered the WHO-led international health system. #TBsky

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Jaime Manzano @jaimemanzano.bsky.social · 24/08/2026

There is a certain irony in where this early statistical use of TB dispensary data took place: Madrid’s Salamanca district—today one of the city’s most expensive housing markets. /4

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Jaime Manzano @jaimemanzano.bsky.social · 24/08/2026

His conclusion wasthat, with such conditions, it was hardly surprising that TB killed 40,000–60,000 people in Spain every year. His prescription? Affordable housing, nutritious food, regulated working hours and sufficient rest. /3

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Jaime Manzano @jaimemanzano.bsky.social · 24/08/2026

The numbers tell their own story: 78% had started working before age 15; 41% worked >10h/day; 68% lived on family incomes below 1 peseta per person; and 67% lived in homes with fewer than one window per room. /2

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Jaime Manzano @jaimemanzano.bsky.social · 24/08/2026

In early 20th-century Madrid, physician Villegas y Bermúdez de Castro studied the social conditions of people with TB attending the María Cristina dispensary (Madrid, Spain). #tuberculosis #history (pic: King Alfonso XIII and Queen Victoria in the garden of the dispensary, inauguration ceremony)🧵

Their Majesties King Alfonso XIII and Queen Victoria in the garden of the María Cristina Anti-Tuberculosis Dispensary (40 Goya Street) during its inauguration ceremony.

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Jaime Manzano @jaimemanzano.bsky.social · 21/08/2026

2026, almost a century later, and we are still having to explain these basic facts, as the framing of people with TB as an individual threat remains dominant in Spain. bsky.app/profile/javi... /6

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Jaime Manzano @jaimemanzano.bsky.social · 21/08/2026

“What are all those people with tuberculosis who walk our streets, attend public events alongside us, and enter our own homes at every turn—taking part in the most varied aspects of social life and even the most intimate moments of family life—if not sources spreading contagion?” (1916,Castellvi) /5

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Jaime Manzano @jaimemanzano.bsky.social · 21/08/2026

This socio-structural approach to TB stood in contrast to the more individualistic perspective also prevalent at the time, as exemplified by this quote from Codina Castellví, a prominent Spanish TB physician of the early 20th century/4

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Jaime Manzano @jaimemanzano.bsky.social · 21/08/2026

As late as 1931, the Second Medical-Social Anti-Tuberculosis Assembly was still calling on public authorities to tackle the housing problem decisively, and adopt measures to reduce the cost of basic necessities, among other recommendation /3

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Jaime Manzano @jaimemanzano.bsky.social · 21/08/2026

...promoting the construction of spacious, well-ventilated and sunlit housing at affordable prices, increasing wages or remuneration where services are inadequately paid, and making work more hygienic and humane in both quantity and quality.”/2

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Jaime Manzano @jaimemanzano.bsky.social · 21/08/2026

At the first Spanish Congress on Tuberculosis (Zaragoza,1908), tuberculosis was described as the consequence of “all forms of deprivation, injustice, error, [and] human judgement.” The second conclusion was, to address TB,“improving the human condition by reducing the cost of basic necessities,.../1

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Jaime Manzano @jaimemanzano.bsky.social · 20/08/2026

The first Wolfheze Conference: Back in 1990, delegates for European countries recommended the pathway towards TB elimination , convening experts from the European TB low incidence countries, and USA, Canada and Japan. You could copy and paste some of their recommendations today and still relevant.

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Reposted by Jaime Manzano

Adam R Houston @healthlawadamh.bsky.social · 24/07/2026

There are multiple places where access delays occur, all deserving attention... and yet, per the actual report, the single longest delay, which is entirely within the control of pharma companies wanting to sell drugs faster, is in... those companies themselves filing new drugs w/ Health Canada.🤔

Screenshot of the four paragraphs of the "Timelines across the access pathway" section of the report, with the sentence "Evidence indicates that submissions to Health Canada are often filed significantly later than in peer jurisdictions, by approximately 262 days (median)Footnote7, delaying entry into the Canadian review process." highlighted.

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Jaime Manzano @jaimemanzano.bsky.social · 26/06/2026

Spain has pledge €1.2 M, but unclear is something else has been approved. What would you say is the fair share for Canada? if we take last ACDC estimate of $1.4 billion, and we make it GDP-based allocated equally to all countries,it would be like $40 miillion? I am interested in this fair share calc

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Jaime Manzano @jaimemanzano.bsky.social · 17/06/2026

G7 declaration on the fight against cancer manages to avoid any mention to affordability. www.elysee.fr/en/G7evian/2... Global medicine spending isexpected to reach $2.3Tn by 2028 and, for oncology, the largest in terms of spending, the annual cost for new medicines has more than tripled in the 10y

elysee.fr

Leaders' call on the fight against cancer. | 2026 G7 SUMMIT

Read the statement.

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Reposted by Jaime Manzano

Jaime Manzano @jaimemanzano.bsky.social · 11/06/2026

🎮 INSERT COIN: FP10 EDITION 🎯 Your mission: ensure that innovations reach the people who need them most. Your enemy: Pricezilla 👾, master of sky-high prices and unequal access. Your power-up? 🛡️Equitable access conditions built in from the very beginning. timeforeuropetolevelup.my.canva.site

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Jaime Manzano @jaimemanzano.bsky.social · 12/06/2026

Do they provide aggregated prices for drugs purchased under that mechanism?

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Jaime Manzano @jaimemanzano.bsky.social · 11/06/2026

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Reposted by Jaime Manzano

Salud por Derecho @saludporderecho.bsky.social · 29/05/2026

🎮 Time for Europe to Level Up Every year, European taxpayers help fund the research behind medicines, vaccines and diagnostics. Yet when these technologies reach the market, affordability and availability are often left to chance. Public investment does not always translate into public benefit.

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Jaime Manzano @jaimemanzano.bsky.social · 28/05/2026

👇No solo es posible, sino que ademas trae de la mano cobeneficios en salud importantes como deciamos aqui:

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Jaime Manzano @jaimemanzano.bsky.social · 18/05/2026

Active TB cases cost LMIC with high TB burdens $3.5 billion more in current annual and future lost earnings and medical expenses than HIV, yet receives substantially less funding gh.bmj.com/content/11/4...

gh.bmj.com

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Reposted by Jaime Manzano

Héctor Tejero @htejero.eurosky.social · 15/05/2025

Aprovechando que hoy es San Isidro, os cuento una de las mejores metáforas para pensar una economía justa dentro de los límites del planeta: la economía de la rosquilla de @kateraworth.bsky.social ky.social 🧵👇 Y lo hago con esta preciosa ilustración de @stherho.bsky.social

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Jaime Manzano @jaimemanzano.bsky.social · 15/05/2026

Y una manera muy importante de relacionar esto con la salud global y la necesidad de evitar la mirada tipo tunel esta en este artículo - Breaking free from tunnel vision for climate change and health journals.plos.org/globalpublic...

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Jaime Manzano @jaimemanzano.bsky.social · 10/05/2026

"The interaction of climate and hantavirus diseases in LAC is likely complex due to the unknown identity of all vertebrate host reservoirs, circulation of multiple hantavirus strains, agricultural practices, climatic changes and challenged public health systems." pmc.ncbi.nlm.nih.gov/articles/PMC...

pmc.ncbi.nlm.nih.gov

Influence of Climatic Factors on Human Hantavirus Infections in Latin America and the Caribbean: A Systematic Review

Background: With the current climate change crisis and its influence on infectious disease transmission there is an increased desire to understand its impact on infectious diseases globally. Hantaviru...

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Jaime Manzano @jaimemanzano.bsky.social · 20/04/2026

also, this: www.theguardian.com/environment/...

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Jaime Manzano @jaimemanzano.bsky.social · 20/04/2026

also the EU in the last year: delayed the ETS2 to 2028 weakened the 2035 combustion engine ban adopted a 2040 climate goal that allows for carbon credit use postponed the deforestation regulation which protects carbon sinks

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