jacionline.bsky.social @jacionline.bsky.social · 04/09/2026The September issue of JACI is now online! Check it out here: jacionline.org/current Read the Editors' Choice summaries from this issue here (free to read/download): authors.elsevier.com/a/1njUaKs2xP... 000
jacionline.bsky.social @jacionline.bsky.social · 05/08/2026The August issue of JACI is now online! Check it out here: jacionline.org/current Read the Editors' Choice summaries from the August issue here (free to read/download): authors.elsevier.com/a/1nYxaKs2xP... 000
jacionline.bsky.social @jacionline.bsky.social · 03/07/2026The July issue of JACI is now online! Check it out here: jacionline.org/current Read the Editors' Choice summaries from the July issue here (free to read/download): authors.elsevier.com/a/1nNL4Ks2xP... 000
jacionline.bsky.social @jacionline.bsky.social · 04/06/2026The June issue of JACI is now online! Check it out here: jacionline.org/current Read the Editors' Choice summaries from the June issue here (free to read/download): authors.elsevier.com/a/1nD8aKs2xP... 000
jacionline.bsky.social @jacionline.bsky.social · 05/05/2026In honor of World Asthma Day, check out the AAAAI journals' collection of related articles www.elsevier.com/subject/heal...elsevier.comWorld Asthma Day 2026 collectionDiscover high-impact articles published in the journals of the American Academy of Allergy, Asthma & Immunology selected for World Asthma Day. 011
jacionline.bsky.social @jacionline.bsky.social · 05/05/2026The May issue of JACI is now online! Check it out here: jacionline.org/current Read the Editors' Choice summaries from the May issue here (free to read/download): authors.elsevier.com/a/1n2bZKs2xP... 000
jacionline.bsky.social @jacionline.bsky.social · 06/04/2026The April issue of JACI is now online! Check it out here: jacionline.org/current Read the Editors' Choice summaries from the February issue here (free to read/download): authors.elsevier.com/a/1mtLaKs2xP... 000
jacionline.bsky.social @jacionline.bsky.social · 28/02/2026The March issue of JACI is now online! Check it out here: jacionline.org/current Read the Editors' Choice summaries from the issue here (free to read/download): authors.elsevier.com/a/1mhOaKs2xP... 000
jacionline.bsky.social @jacionline.bsky.social · 10/02/2026The meeting abstracts for the 2026 AAAAI Annual Meeting are now online. Here is the link to the index on our homepage, including late breaking abstracts: www.jacionline.org/programs_abs...jacionline.orgProgram and Abstracts of Papers to be Presented During Scientific Sessions: Journal of Allergy and Clinical Immunology 000
jacionline.bsky.social @jacionline.bsky.social · 04/02/2026The February issue of JACI is now online! Check it out here: jacionline.org/current Read the Editors' Choice summaries from the February issue here (free to read/download): authors.elsevier.com/a/1mYyZ_25Pv... 000
jacionline.bsky.social @jacionline.bsky.social · 05/01/2026The January issue of JACI is now online! Check it out here: jacionline.org/current Read the Editors' Choice summaries from the January issue here (free to read/download): authors.elsevier.com/a/1mOPaKs2xL... 000
jacionline.bsky.social @jacionline.bsky.social · 04/12/2025The December issue of JACI is now online! Check it out here: jacionline.org/current Read the Editors' Choice summaries from the December issue here (free to read/download): authors.elsevier.com/a/1mD9bKs2xL... 000
jacionline.bsky.social @jacionline.bsky.social · 05/11/2025The November issue of JACI is now online! Check it out here: jacionline.org/current Read the Editors' Choice summaries from the November issue here (free to read/download): authors.elsevier.com/a/1m2z7Ks2xL... 000
jacionline.bsky.social @jacionline.bsky.social · 08/10/2025Check out this Newsweek article that features research in JACI: www.newsweek.com/passenger-ea...newsweek.comGen Z woman eats snack on plane—horror at announcement that comes next"I was planning on sleeping during the flight … and wanted to have a quick bite," the young woman told Newsweek. 000
jacionline.bsky.social @jacionline.bsky.social · 06/10/2025Did you know JACI features a list of our recent cutting-edge articles on Immune dysregulation? Check it out here - all Open Access!buff.lyFree Access: Cutting-Edge Immune Dysregulation Articles: Journal of Allergy and Clinical ImmunologyDownload started. 000
jacionline.bsky.social @jacionline.bsky.social · 03/10/2025The October issue of JACI is now live, featuring a theme on the thymus. View the issue here! buff.ly/BEHXa0l 000
jacionline.bsky.social @jacionline.bsky.social · 03/10/2025The latest issue of JACI has now posted - check out the Editors Choice here:buff.ly 000
jacionline.bsky.social @jacionline.bsky.social · 05/09/2025Article from the UK focusing on advocacy for peanut allergy prevention drawn in part from current JACI article (pubmed.ncbi.nlm.nih.gov/36521802/) on early introduction of peanuts. www.the-independent.com/news/uk/home...the-independent.comGreater focus on allergy prevention by NHS needed to protect children – MPLabour’s Becky Gittins is pressing the Government to adopt advice which recommends babies are weaned early if they show signs of an allergy. 000
jacionline.bsky.social @jacionline.bsky.social · 04/09/2025The September issue of JACI is now online! Check it out here: jacionline.org/current This month's theme focuses on Personalized Medicine. Special thanks to Mohamed Shamji, who helped coordinate this issue. Read the Editors' Choice summaries here (free): authors.elsevier.com/a/1ljA5Ks2xL... 000
jacionline.bsky.social @jacionline.bsky.social · 05/08/2025The August issue of JACI is now online! jacionline.org/current This month's theme focuses on Complement. Special thanks to Kathleen Sullivan, who helped coordinate this issue. Read the Editors' Choice summaries from the August issue here (free): authors.elsevier.com/a/1lYd6Ks2xL... 010
jacionline.bsky.social @jacionline.bsky.social · 23/07/2025While over 50% of U.S. children test positive for common allergens, only ~7% of Amish children do. Asthma rates run just 1–2% in Amish Children vs. ~8–10% in non-Amish kids. Their secret? See this Washington Post article that cites research from JACI. wapo.st/4odEBmqwapo.stAllergies seem nearly impossible to avoid — unless you’re AmishOne Amish community living in northern Indiana is considered one of the least allergic populations ever measured in the developed world. 020
jacionline.bsky.social @jacionline.bsky.social · 04/07/2025The July issue of JACI is now online! Check it out here: jacionline.org/current This month's theme focuses on Endotypes in Allergy/Immunology. Read the Editors' Choice summaries from the June issue here (free to read/download): authors.elsevier.com/a/1lN0bKs2xL... 000
jacionline.bsky.social @jacionline.bsky.social · 18/06/2025Clinical trials of therapies for asthma and food allergy are complex, and there is intense interest in the development of biomarkers to predict natural disease history and response to therapy. Read a summary of a US FDA-hosted workshop discussion. bit.ly/4juKdVDbit.lyBiomarker-driven drug development for allergic diseases and asthma: An FDA public workshopThe US Food and Drug Administration (FDA) hosted a workshop on February 22, 2024, to discuss the status of biomarkers in drug development for allergic… 011
jacionline.bsky.social @jacionline.bsky.social · 17/06/2025Our understanding of the genetic etiology of allergic diseases has grown significantly in recent years. Read about key advances in the field, with a focus on common genetic variants that increase disease risk. bit.ly/45CWrIrbit.lyUpdate on the genetics of allergic diseasesThe field of genetic etiology of allergic diseases has advanced significantly in recent years. Shared risk loci reflect the contribution of genetic fa… 000
jacionline.bsky.social @jacionline.bsky.social · 16/06/2025Climate change is affecting outdoor and indoor allergen exposures, and diagnostic and treatment strategies should limit exposure and facilitate desensitization. An American Academy of Allergy, Asthma & Immunology Work Group Report shares 4 steps. Read on. bit.ly/4kP95bBbit.lyA call to standardize exposure and outcome measures in birth cohort studies on asthma and allergic diseases 000
jacionline.bsky.social @jacionline.bsky.social · 13/06/2025Birth cohort studies have provided invaluable insights into risk factors for allergic diseases and asthma in children. They also have their limitations. Should we standardize population descriptors, exposures, and outcomes measures from diverse cohorts? bit.ly/4mJBHoJbit.lyA call to standardize exposure and outcome measures in birth cohort studies on asthma and allergic diseases 000
jacionline.bsky.social @jacionline.bsky.social · 12/06/2025Traditionally, birth cohort studies are longitudinal, prospective observational studies of parents and their children. A Paradigms and perspectives piece discusses how birth cohort studies are evolving to incorporate methodologic innovations. Read on. bit.ly/3SyhzInbit.lyThe normal, the abnormal, and the at risk: How can old and new birth cohort studies help? 000
jacionline.bsky.social @jacionline.bsky.social · 11/06/2025The use of administrative data, or data from research-independent repositories, offers a valuable tool for birth cohort studies. It also brings challenges. How have administrative data have enhanced asthma, allergy, and immune disorder birth cohorts? bit.ly/43M6fgKbit.lyAdvancing birth cohort studies using administrative and other research-independent data repositories: Opportunities and challengesThe birth cohort study design is an essential epidemiologic tool for investigating the developmental origins of health and disease. Birth cohorts have… 000
jacionline.bsky.social @jacionline.bsky.social · 05/06/2025Studies of human IgE and its targeted epitopes on allergens have been limited. A study now shares a molecular map of the IgE antibody response to key peanut allergens. The issue also includes editorial commentary on the findings. bit.ly/3ZhS6Xcbit.lyStructural determinants of peanut-induced anaphylaxisHuman IgE mAbs recognizing peanut allergens have recently become available, but we lack a detailed understanding of how these IgEs target allergens.We… 010
jacionline.bsky.social @jacionline.bsky.social · 04/06/2025The June issue of JACI is now online! Check it out here: jacionline.org/current This month's theme focuses on Birth Cohorts. Special thanks to Tina Hartert and Andrea Apter, who helped coordinate this issue. Read the Editors' Choice summaries here: authors.elsevier.com/a/1lCq7Ks2xL... 000
jacionline.bsky.social @jacionline.bsky.social · 04/06/2025Data from a phase 2 trial of GR1802, a novel anti-IL-4Ra monoclonal antibody, for the treatment of patients with uncontrolled chronic rhinosinusitis with nasal polyps suggest that the treatment is well-tolerated and effective. Here’s more. bit.ly/44F8VPnbit.lyEfficacy and safety of GR1802 in uncontrolled chronic rhinosinusitis with nasal polyps: Placebo-controlled phase 2 trialAnti–IL-4 receptor subunit alpha (IL-4Rα) treatments can effectively treat eosinophilic chronic rhinosinusitis with nasal polyps (ECRSwNP). However, t… 000
jacionline.bsky.social @jacionline.bsky.social · 02/06/2025Rocuronium is widely used to assist in mechanical ventilation. In a small number of anesthesia cases, it can lead to anaphylaxis. New data shed light on the underlying mechanisms and suggest novel diagnostic tools for rocuronium hypersensitivity. bit.ly/3SJJ15Hbit.lyAntibody-secreting cell repertoires hold high-affinity anti-rocuronium specificities that can induce anaphylaxis in vivoNeuromuscular blocking agents (NMBAs) are muscle relaxants used to assist mechanical ventilation but lead in 1 per 10,000 anesthesia cases to severe a… 000
jacionline.bsky.social @jacionline.bsky.social · 30/05/2025Human IgE mAbs that recognize peanut allergens are now available. How do these IgEs target allergens? Read about a structural map of the IgE antibody response to two key peanut allergen proteins. The issue includes editorial commentary on the findings. bit.ly/3Zftm1Obit.lyDirect epitope study using human IgE mAbs against peanut allergens 000
jacionline.bsky.social @jacionline.bsky.social · 28/05/2025New data suggest that chronic rhinosinusitis with nasal polyps pathobiology may involve autoreactive humoral immunity, with some cases exhibiting molecular mimicry-driven autoimmune features triggered by microbial infections. Read the Editors’ Choice paper. bit.ly/3YP6Dtfbit.ly 000
jacionline.bsky.social @jacionline.bsky.social · 27/05/2025Short-chain fatty acids have been shown to be locally produced in areas of the body other than the gut in response to disease. What role might local short-chain fatty acid concentrations hold in obstructive airway diseases? Here’s a Brief report. bit.ly/430eTJybit.ly 000
jacionline.bsky.social @jacionline.bsky.social · 26/05/2025Why do some upper respiratory illnesses provoke asthma exacerbations while the majority do not? An Editors’ Choice study identifies transcriptome-wide gene expression changes associated with common colds that progress to asthma exacerbation. Learn more. bit.ly/44EGKQLbit.ly 010
jacionline.bsky.social @jacionline.bsky.social · 23/05/2025Airway inflammation plays a key role in asthma, and the contributing molecular pathways, especially in type 2 inflammation characterized by eosinophilia and higher fractional exhaled nitric oxide, are not clear. Read new findings here. bit.ly/4jRGcM1bit.ly 000
jacionline.bsky.social @jacionline.bsky.social · 22/05/2025Rhinoconjunctivitis phenotypes are described based on aeroallergen sensitization and symptom severity and seasonality. Do these phenotypes fully reflect patterns of symptoms at a population level in children with asthma? Read Editors’ Choice findings. bit.ly/4keX9jcbit.ly 000
jacionline.bsky.social @jacionline.bsky.social · 21/05/2025Since 1993, the American Academy of Allergy, Asthma & Immunology has spent almost $11 million in Faculty Development awards to support the growth of our junior colleagues. Almost all have gone on to attain faculty appointments. Meet the 2025 awardees. bit.ly/3S4boeTbit.ly 000
jacionline.bsky.social @jacionline.bsky.social · 20/05/2025Chronic rhinosinusitis is associated with a disruption of the sinonasal microbiome, and a better understanding may open new treatments. Here’s a Paradigms and perspectives review on epithelial cell innate immunity and important open questions. bit.ly/3SrJCctbit.ly 000
jacionline.bsky.social @jacionline.bsky.social · 19/05/2025Dysregulated function of the prostaglandin E2 (PGE2) system contributes to many features of chronic rhinosinusitis with nasal polyps and aspirin-exacerbated respiratory disease. Read what we know and the pathogenic and therapeutic implications. bit.ly/3ETbVgMbit.ly 000
jacionline.bsky.social @jacionline.bsky.social · 16/05/2025There have been major advances in the treatment of chronic rhinosinusitis with nasal polyps, but disease returns upon discontinuation and there is no targeted anti-inflammatory approach. Recent data on epithelial barrier dysfunction suggest new avenues. bit.ly/43FN60bbit.ly 000
jacionline.bsky.social @jacionline.bsky.social · 15/05/2025An alarmin is a molecule that is rapidly released to alert the immune system through the engagement of specific receptors on immune cells. Learn what we know about the role of the novel alarmin TNF-like cytokine 1A (TL1A) in inflammatory conditions. bit.ly/436CjM5bit.lyTL1A, a novel alarmin in airway, intestinal, and autoimmune disordersThe term alarmin denotes a broad class of molecules rapidly released to alert the immune system through the engagement of specific receptors on immune… 000
jacionline.bsky.social @jacionline.bsky.social · 15/05/2025Hyperinflammation has been associated with rare autoinflammatory disorders, but advances in omics technologies have revealed it to be more common, occurring in sepsis and severe coronavirus disease 2019. Learn about the key role of omics in this shift. bit.ly/4jPeUpDbit.lyFrom rare to more common: The emerging role of omics in improving understanding and treatment of severe inflammatory and hyperinflammatory conditionsInflammation is a pathogenic driver of many diseases, including atherosclerosis and rheumatoid arthritis. Hyperinflammation can be seen as any inflamm… 000
jacionline.bsky.social @jacionline.bsky.social · 14/05/2025Hyperinflammation has been associated with rare autoinflammatory disorders, but advances in omics technologies have revealed it to be more common, occurring in sepsis and severe coronavirus disease 2019. Learn about the key role of omics in this shift. bit.ly/4jPeUpDbit.lyFrom rare to more common: The emerging role of omics in improving understanding and treatment of severe inflammatory and hyperinflammatory conditionsInflammation is a pathogenic driver of many diseases, including atherosclerosis and rheumatoid arthritis. Hyperinflammation can be seen as any inflamm… 000
jacionline.bsky.social @jacionline.bsky.social · 13/05/2025Deficiency of ADA2 causes a complex phenotype of autoinflammation and immunodeficiency. The mechanisms underlying the disease on a cellular level remain unclear. A review inspects characteristics of the ADA2 protein and its proposed function. bit.ly/4dbR58Pbit.lyGetting to know adenosine deaminase 2 deficiency inside and outTen years after the description of the first cohorts of patients with adenosine deaminase (ADA2) deficiency (DADA2), the pathomechanisms underlying th… 000
jacionline.bsky.social @jacionline.bsky.social · 12/05/2025Aspirin exacerbated respiratory disease occurs in an estimated 15% of patients with chronic rhinosinusitis with nasal polyps and/or asthma. Read a review of novel mechanistic findings and recent advancements in clinical understanding and management. bit.ly/44pBsZdbit.lyClinical and mechanistic advancements in aspirin exacerbated respiratory diseaseAspirin-exacerbated respiratory disease (AERD) is characterized by the clinical triad of chronic rhinosinusitis with nasal polyps, asthma, and a hyper… 000
jacionline.bsky.social @jacionline.bsky.social · 09/05/2025Three biologic therapies are currently approved to treat chronic rhinosinusitis with nasal polyps. Here’s a review of clinical trial and real-world data on effectiveness and safety, outcomes of biologic therapy versus surgery, and future directions. bit.ly/3YAEB4Cbit.lyClinical efficacy and mechanisms of biologics for chronic rhinosinusitis with nasal polypsThe management of chronic rhinosinusitis with nasal polyps (CRSwNP) can be challenging, particularly when standard treatments including intranasal cor… 010
