iiinova — where your digital self keeps evolving

Reposted by @iwangtoknow.bsky.social

DaganLab @daganlab.bsky.social · 17/04/2026

We will be advertising soon a PhD position in this consortium. Interested candidates (experimental/computational) are welcome to informally reach out to Tal Dagan. Practical experience (e.g., MSc thesis) in microbial genetics or molecular evolution (with programming) is a prerequisite.

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Reposted by @iwangtoknow.bsky.social

DaganLab @daganlab.bsky.social · 08/10/2025

Happy to introduce SegMantX. Analyzing #plasmid we find that most duplications are MGE-driven. Additional use cases include detection of DNA transfer between replicons and examination of plasmid sequence similarity. Try it out! doi.org/10.1093/molb...

doi.org

SegMantX: a novel tool for detecting DNA duplications uncovers prevalent duplications in plasmids

Abstract. Segmental duplications play an important role in genome evolution via their contribution to copy-number variation, gene-family diversification an

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Reposted by @iwangtoknow.bsky.social

RdRp Summit @rdrpsummit.bsky.social · 09/05/2025

Lucaprot leverages AI to discover highly-divergent RNA-dependent RNA polymerase sequences, completely revolutionizing the field of RNA Virus discovery! We are ecstatic to have Xin Hou (@xinhou.bsky.social) as one of our invited speakers at the #RdRpSummit2025!

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Reposted by @iwangtoknow.bsky.social

DaganLab @daganlab.bsky.social · 12/02/2025

Imagine that you are a low-copy extra-chromosomal genetic elements invading a host cell. What’s your best strategy to survive? Check our new study of prokaryotic #plasmid for the answer! www.biorxiv.org/content/10.1... led by Johannes Effe with @iwangtoknow.bsky.social and more! (not on bsky)

biorxiv.org

Persistence of large conjugative plasmids relies on the combination of active partitioning and addiction mechanisms

Extrachromosomal and mobile genetic elements, including transposable elements, plasmids, and accessory chromosomes, are found across all domains of life. The replication and segregation of elements in...

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