VERY HAPPY to share our new paper in Aging Cell (doi.org/10.1111/acel...). We discovered the unexpected roles of ER stress in youthful skin maintenance, using ultra-short lived killifish and spacial transcriptomics PIC. #aging #killifish
doi.org
ER Stress Ire1‐Xbp1s Pathway Maintains Youthful Epidermal Basal Layer Through the Regulation of Cell Proliferation
In young epidermal basal layer, the Ire1-Xbp1s endoplasmic reticulum (ER) stress-response pathway maintains cell proliferation by activating the cell cycle regulator Vcp, whereas the age-dependent de....
