Ischemia @ischemia1327.bsky.social · 13/08/2026We are looking for a highly motivated and skilled senior post-doc researcher to apply to the programme “Starting up young FRM (Fondation pour la Recherche Médicale) teams” on “Ischemia” or “Ischemia-reperfusion" lesions Contact: Prof. sebastien.roger@univ-tours.fr, director. 📞0033 2 47 36 61 30 101
Ischemia @ischemia1327.bsky.social · 15/07/2026Our team at the final COST Action PRESTO meeting and European Purine Meeting #EPM2026, at Bordeaux University, July 2026 Thomas Duret Poster: “The P2X4 purinergic receptor controls the #autophagy-related release of small extracellular vesicles (#EVs) from mammary #cancer cells” 000
Ischemia @ischemia1327.bsky.social · 15/07/2026Our team at the final COST Action PRESTO meeting and European Purine Meeting #EPM2026, at Bordeaux University, July 2026 Wiam Echchih Poster: “Efficacy of #inflammasome modulation to prevent #myocardial ischemia-reperfusion #injuries” 000
Ischemia @ischemia1327.bsky.social · 15/07/2026Final COST Action PRESTO meeting and European Purine Meeting #EPM2026, at Bordeaux University, July 2026 Marylou Pichonnière @maryloupi.bsky.social Poster: “Identification of proteomic #biomarkers for #kidney #graft quality: focus on extracellular vesicles released during #hypothermic perfusion” 000
Ischemia @ischemia1327.bsky.social · 15/07/2026Final COST Action PRESTO meeting and European Purine Meeting #EPM2026, at Bordeaux University, July 2026 Jeferson Stabile Oral communication: “From kidney to #vessel : Indoxyl sulfate links tubular injury to #purinergic #signaling and #vasculature dysfunction in experimental acute kiney injury” 000
Ischemia @ischemia1327.bsky.social · 15/07/2026Final COST Action PRESTO meeting and European Purine Meeting #EPM2026, at @univbordeaux.bsky.social, July 2026 Oumnia Benouna @oumniaben.bsky.social Best oral com. award! “#P2X4 modulates #autophagy in renal epithelial proximal tubular cells in an in vitro model of ischemia-reperfusion” 000
Ischemia @ischemia1327.bsky.social · 15/07/2026Our team at the final COST Action PRESTO meeting and European Purine Meeting #EPM2026, at @univbordeaux.bsky.social, July 2026 Sébastien Roger @sebroger.bsky.social #Plenary Lecture: “Roles of the P2X4 purinergic receptor in ischemic conditions” 000
Ischemia @ischemia1327.bsky.social · 15/07/2026Members of our research Laboratory, from Tours University and @chrudetours.bsky.social, were present at the final COST Action PRESTO meeting and at the European Purine Meeting #EPM2026 at @univbordeaux.bsky.social to present recent data from the lab on #ischemia and #reperfusion lesions! 110
Ischemia @ischemia1327.bsky.social · 13/07/2026International Society on Thrombosis and Haemostasis @isth.org 2026 in Paris, July 11-15: Oral communication of Simon Chesseron, PhD student, on "Platelet factor 4 and cardiac fibrosis: pathophysiological and therapeutic implications" 021
Ischemia @ischemia1327.bsky.social · 13/07/2026International Society on Thrombosis and Haemostasis @isth.org 2026 in Paris, July 11-15: Poster communication of Estelle Archer, PhD student, on "Heparin-induced thrombocytopenia (HIT): towards a more performant serotonin release assay (SRA) using polyvinyl sulfonate (PVS) in place of heparin" 021
Ischemia @ischemia1327.bsky.social · 13/07/2026International Society on Thrombosis and Haemostasis (ISTH) 2026 in Paris, July 11-15: Oral communication of Caroline Vayne on "Related protein 1 (Drp1) phosphorylation provides a new strategy for platelet function testing in the diagnosis of HIT and VITT" 120
Reposted by IschemiaThe French Purine Club @frenchpurine.bsky.social · 23/12/2025📢 Save the date! 3rd European Purine Meeting 🗓️ 1–3 July 2026 | 📍 Bordeaux, France (Univ. Bordeaux, Campus Victoire) Preceded by the final PRESTO meeting: 30 June–1 July 2026 🌐 Call for Symposia now open: live.eventtia.com/en/european-... #P1 #P2X#P2Y #ATP #adenosine #purinergic #signalling 233
Ischemia @ischemia1327.bsky.social · 02/07/2025Our PhD student, Johanna Augros, represented our lab exceptionally well at the International Society on Thrombosis and Haemostasis @isth.org meeting that took place in Washington. See you next year at the ISTH next meeting in Paris! 030
Ischemia @ischemia1327.bsky.social · 01/07/2025Members of INSERM UMR1327 Ischemia: Mohammed ELMALLAH, Marylou PICHONNIERE and Oumnia BENOUNA were pleased to present their work yesterday, at the Annual meeting of the @frenchpurine.bsky.social in Paris. A meeting enriched by relevant scientific discussions. 011
Ischemia @ischemia1327.bsky.social · 26/05/2025We thank the organizers of the PRESTO COST action meeting (Dublin, Ireland, 22-24/05), on the topic "Purinergic signalling: from bench-to-bedside, where are we now?" Congratulations to our unit members W. ECHCHIH, M. PICHONNIERE, M. ElMALLAH, A. HERAUD-MELEY and O. BENOUNA for their presentations. 010
Reposted by IschemiaPharmacologie Médicale Tours @pharmacotours.bsky.social · 14/05/2025Synthèse sur "Les anticorps monoclonaux dans les maladies immuno-inflammatoires" dans le dernier N° de La Lettre du Pharmacologue, consacré à la pharmacologie de l'inflammation par G. Paintaud, O. Le Tilly, D. Ternant, C. Desvignes et @theodorabejan.bsky.social www.edimark.fr/revues/la-le...edimark.frLes anticorps monoclonaux dans les maladies immuno-inflammatoires | G. Paintaud, O. Le Tilly, D. Ternant, C. Desvignes, T. Bejan-AngoulvantEn 26 ans, 44 anticorps monoclonaux (AcMo), se fixant sur 28 antigènes cibles différents, ont obtenu une indication dans au moins une maladie immuno-inf 013
Ischemia @ischemia1327.bsky.social · 12/05/2025Yesterday, Oumnia Benouna, Ana Valéria Vinhais da Silva, Johanna Augros, Marylou Pichonnière, Claire Hosemans and Wiam Echchih (UMR1327), participated to a 10 km "Parcours du cœur" at Bergeonnerie Lake (Tours), a walk dedicated to raising awareness about heart health. Thanks to the organizers! 000
Reposted by IschemiaÀ Tours de Bulles @atoursdebulles.bsky.social · 11/04/2025Nous avons le plaisir de participer au programme "Ma thèse en BD" de l'université de Tours. Les planches 2024-2025, réalisées par 3 dessinatrices/teurs avec 5 doctorant.es, sont téléchargeables et feront l'objet de plusieurs expos, notamment lors du festival 2025 saps.univ-tours.fr/decouvrez-le...saps.univ-tours.frDécouvrez les planches de la nouvelle édition "Ma thèse en BD" (2024-25)Suite à un appel à participation lancé en septembre dernier, 5 doctorants et doctorantes ont été sélectionnés pour la 3e édition de 'Ma thèse en BD'. Le défi : illustrer ses travaux de recherche et so... 1148
Ischemia @ischemia1327.bsky.social · 10/04/2025Credibility assessment of a mechanistic model of atherosclerosis to predict cardiovascular outcomes under lipid-lowering therapy Denis Angoulvant @dangoulvant.bsky.social is coauthor of this paper by Yishu Wang et al., published in NPJ Digit Med rdcu.be/ehav0rdcu.beCredibility assessment of a mechanistic model of atherosclerosis to predict cardiovascular outcomes under lipid-lowering therapynpj Digital Medicine - Credibility assessment of a mechanistic model of atherosclerosis to predict cardiovascular outcomes under lipid-lowering therapy 011
Ischemia @ischemia1327.bsky.social · 04/04/2025Prognosis of patients with acute myocardial infarction in the setting of COVID-19: A French nationwide observational study by Ahmad Abou Hamed, Maeva Gourraud, Thibaud Genet, François Barbier, Denis Angoulvant, Laurent Fauchier and Fabrice Ivanes www.sciencedirect.com/science/arti...sciencedirect.comPrognosis of patients with acute myocardial infarction in the setting of COVID-19: A French nationwide observational studyThe prognosis of patients with acute myocardial infarction (AMI) in the setting of coronavirus disease 2019 (COVID-19) remains uncertain.To evaluate p… 000
Ischemia @ischemia1327.bsky.social · 14/03/2025Conférences Sport & Santé le 21 mars à MAME (Tours) à 17h30 Un événement organisé par Tours Autogreffe 000
Reposted by IschemiaPharmacologie Médicale Tours @pharmacotours.bsky.social · 12/03/2025Nous sommes à la recherche de candidat.es pour notre poste d'Assistant Hospitalo-universitaire, qui sera disponible en novembre 2025. Contacts : Theodora Bejan-Angoulvant @theodorabejan.bsky.social ou David Ternant Merci de reposter ! 013
Ischemia @ischemia1327.bsky.social · 11/03/2025Cardiovascular risk associated with glucagon-like peptide-1 receptor agonists versus other conventional glucose-lowering drugs in patients with type-2 diabetes: protocol for a nationwide observational comparative study in routine care bmjopen.bmj.com/content/15/1... 000
Reposted by IschemiaPharmacologie Médicale Tours @pharmacotours.bsky.social · 06/03/2025Publication of the PHARBEVACOL study protocol: Bevacizumab-based chemotherapy adaptive to PK of bevacizumab in first-line treatment of patients with unresectable metastatic colorectal cancer: A double-blind, multicenter, randomized phase III trial study www.sciencedirect.com/science/arti...sciencedirect.comBevacizumab-based chemotherapy adaptive to pharmacokinetic of bevacizumab in first-line treatment of patients with unresectable metastatic colorectal cancer: A double-blind, multicenter, randomized ph...Bevacizumab shows inter-individual pharmacokinetic variability, with an exposure-response relationship in metastatic colorectal cancer (mCRC) patients… 021
Reposted by IschemiaStand Up for Science Paris et région parisienne @sufs-paris-rp.bsky.social · 04/03/2025Bonjour, une action est signalée à Tours : standupforscience.fr/tous-les-eve... 👍standupforscience.fr Tous les évènements | Stand Up For Science France 083
Ischemia @ischemia1327.bsky.social · 04/03/2025Outcomes in Atrial Fibrillation Patients with Different Clinical Phenotypes: Insights from the French Population by A.M. Fawzy, A. Bisson, L. Lochon, T. Lenormand, G.Y.H. Lip and L. Fauchier @liverpoolccs.bsky.social @chrudetours.bsky.social @chuorleans.bsky.social www.mdpi.com/3171158mdpi.comOutcomes in Atrial Fibrillation Patients with Different Clinical Phenotypes: Insights from the French PopulationBackground: Atrial fibrillation (AF) patients represent a clinically complex, heterogeneous population comprising multiple homogeneous cohorts. Purpose: We aimed to identify the common clinical phenot... 000
Ischemia @ischemia1327.bsky.social · 03/03/2025@dangoulvant.bsky.social is coauthor of Quitting versus using aspirin therapy in patients with stabilized coronary artery disease after stenting who require long-term oral anticoagulation: Rationale for and design of the AQUATIC double-blind randomized trial www.sciencedirect.com/science/arti...sciencedirect.comAssessment of quitting versus using aspirin therapy in patients with stabilized coronary artery disease after stenting who require long-term oral anticoagulation: Rationale for and design of the AQUAT...Antithrombotic management in patients with chronic coronary syndrome and previous stent implantation who require long-term oral anticoagulation is hig… 010
Ischemia @ischemia1327.bsky.social · 27/02/2025TMA from peptide receptor radionuclide therapy P Delalande, M Bobot, M Essig, C Simon, AP Jonville-Béra, C Barbet, B Sautenet, V Maisons, T Carsuzaa, F Bruyère and JM Halimi @aphm-chu-marseille.bsky.social @hopambroisepare.bsky.social @chrudetours.bsky.social www.sciencedirect.com/science/arti...sciencedirect.comThrombotic Microangiopathy From Peptide Receptor Radionuclide Therapy 000
Ischemia @ischemia1327.bsky.social · 26/02/2025Towards Personalized Prevention: The Role of ECG in Cardiovascular Risk Prediction for Type 2 Diabetes in Eur J Prev Cardiol 2025 by A. Bisson and D. Angoulvant, Inserm UMR1327 and Departments of Cardiology of @chrudetours.bsky.social and @chuorleans.bsky.social academic.oup.com/eurjpc/artic...academic.oup.comTowards Personalized Prevention: The Role of ECG in Cardiovascular Risk Prediction for Type 2 DiabetesArnaud Bisson, Denis Angoulvant; Towards Personalized Prevention: The Role of ECG in Cardiovascular Risk Prediction for Type 2 Diabetes, European Journal o 000
Ischemia @ischemia1327.bsky.social · 20/02/2025Imaging flow cytometry for the diagnosis of HIT by Carré J, Demont Y, Mouton C, Vayne C, Guéry EA, Voyer A, Garçon L, Le Guyader M, Demagny J @chuamiens.bsky.social @chu-bordeaux.fr @chrudetours.bsky.social in Br J Haematol 2025 @bsochaem.bsky.social onlinelibrary.wiley.com/doi/10.1111/...onlinelibrary.wiley.comImaging flow cytometry as a novel approach for the diagnosis of heparin‐induced thrombocytopeniaImaging flow cytometry (IFC) combines the advantages of flow cytometry (FC) and microscopy to provide detailed morphological insights into platelets. In this study, we evaluated the performance of mo... 000
Reposted by IschemiaArmelle Rancillac 🔬 @rancillac.bsky.social · 12/02/2025Nous avons le plaisir de vous inviter aux 3ᵉ Journées Scientifiques du French Purine Club ! 📅 30 juin à 14h au 1er juillet à 12h 📍 ESPCI, 10 rue Vauquelin, 75005 Paris 🔗 docs.google.com/forms/d/e/1F... 💡 Pensez aussi à votre cotisation annuelle ➡️ bit.ly/4hOcar6 Nous espérons vous y voir nombreux !docs.google.com3e Journées Scientifiques du French Purine ClubESPCI, 10 rue Vauquelin, 75005 Paris 043
Ischemia @ischemia1327.bsky.social · 14/02/2025A clinician viewpoint on the 2024 European guidelines on the management of patients with atrial fibrillation by L Fauchier UMR1327 and @chrudetours.bsky.social, JC Deharo @aphm-chu-marseille.bsky.social, F Sacher @chu-bordeaux.fr and A Cohen @ap-hp.bsky.social www.sciencedirect.com/science/arti...sciencedirect.comA clinician viewpoint on the 2024 European guidelines on the management of patients with atrial fibrillation 010
Reposted by IschemiaPharmacologie Médicale Tours @pharmacotours.bsky.social · 03/02/2025Evaluation of efficacy and safety of rituximab in patients with progressive interstitial lung disease with inflammatory component (EvER-ILD2): A multicentre double-blind placebo-controlled randomized trial by M Ferreira, T Bejan-Angoulvant, S Marchand-Adam et al. pubmed.ncbi.nlm.nih.gov/39693827/pubmed.ncbi.nlm.nih.govEvaluation of efficacy and safety of rituximab in patients with progressive interstitial lung disease (ILD) with inflammatory component (EvER-ILD2): A multicentre double-blind placebo-controlled rando...NCT05596786 (clinicaltrials.gov), EU-CT number 2022-500,375-31-00 (European Medicines agency). 011
Ischemia @ischemia1327.bsky.social · 03/02/2025P2 purinergic receptors at the heart of pathological left ventricular remodeling following acute myocardial infarction a review by AV Vinhais da Silva, S Chesseron, O Benouna, J Rollin, S Roger, T Bourguignon, S Chadet and F Ivanes Am J Physiol Heart Circ Physiol pubmed.ncbi.nlm.nih.gov/39884315/pubmed.ncbi.nlm.nih.govP2 purinergic receptors at the heart of pathological left ventricular remodeling following acute myocardial infarction - PubMedPathological left ventricular remodeling is a complex process following an acute myocardial infarction, leading to architectural disorganization of the cardiac tissue. This phenomenon is characterized... 000