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IMPORTANT EU Project

@importanteuproject.bsky.social
16 followers 10 following 24 posts

IMPlementing geriatric assessment for dose Optimization of CDK 4/6-inhibitors in older bReasT cAncer patieNTs

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IMPORTANT EU Project @importanteuproject.bsky.social · 29/09/2026
IMPORTANT at the Nordic #BreastCancer Meeting 2026! IMPORTANT was presented as an example of a #PragmaticClinicalTrial designed to generate evidence relevant to everyday oncology practice. The right dose, for the right patient, at the right time! #EUCancerMission nordiskt-brostcancermote.mkon.se
nordiskt-brostcancermote.mkon.se
Nordiskt Bröstcancermöte
Nordiskt Bröstcancermöte
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IMPORTANT EU Project @importanteuproject.bsky.social · 29/09/2026
The IMPORTANT Patient Companion was presented by Maryam Yeganeh (FHNW) at AI Open House Basel, an event with more than 100 participants Showcasing patient-centred healthcare navigation & decision-making through digital innovation #IMPORTANTProject #DigitalHealth #PatientCentredCare #EUCancerMission
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IMPORTANT EU Project @importanteuproject.bsky.social · 29/09/2026
IMPORTANT at the Nordic Congress on Breast Cancer 2026! Prof. Antonis Valachis presented IMPORTANT as an example of treatment optimisation during his talk "Treatment reduction–safe or risky?" The right dose, for the right patient, at the right time #IMPORTANTProject #BreastCancer #EUCancerMission
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IMPORTANT EU Project @importanteuproject.bsky.social · 17/09/2026
IMPORTANT Newsletter #21 is out! All 16 trial sites are open for recruitment, with 146 patients included and 134 randomized as of 31 August 2026 Read the latest updates from the IMPORTANT project important-project.com #IMPORTANTProject #HorizonEurope #BreastCancer #ClinicalTrials #GeriatricOncology
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IMPORTANT EU Project @importanteuproject.bsky.social · 18/08/2026
📢 New publication from #IMPORTANTProject! The partner University of Patras has published new research exploring how digital twins, mechanistic modelling & AI can support more personalised approaches in geriatric oncology & care for older people with cancer. 🔗 www.frontiersin.org/journals/art...
doi.org
Frontiers | From mechanistic models to artificial intelligence: exploring the potential of digital twins in geriatric oncology
This survey explores how machine learning and artificial intelligence (AI) can be integrated with mechanistic models to create more accurate, dynamic, predic...
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IMPORTANT EU Project @importanteuproject.bsky.social · 27/07/2026
📣 IMPORTANT Newsletter #19 is out! 13 sites are open, 133 patients have been included, 124 randomized & 3 new Greek sites are preparing to recruit. Recruitment continues until April 2027 🌐 important-project.com #IMPORTANTTrial #GeriatricOncology #BreastCancerResearch #CancerMission #HorizonEurope
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IMPORTANT EU Project @importanteuproject.bsky.social · 27/07/2026
📢 New #IMPORTANT Project publication: a multinational survey reveals wide variation in CDK4/6 inhibitor dosing for older patients with metastatic breast cancer—highlighting the need for stronger clinical evidence. 🔗 www.geriatriconcology.net/article/S187... #GeriatricOncology #BreastCancer
geriatriconcology.net
CDK4/6 inhibitor dose patterns among older patients with metastatic breast cancer: A multinational survey study
Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) combined with endocrine therapy (ET) improve outcomes in HR+/HER2− metastatic breast cancer (MBC) [1–5]. However, older adults remain underrepresented ...
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IMPORTANT EU Project @importanteuproject.bsky.social · 18/06/2026
📢 IMPORTANT Newsletter #18 is out! Updates on recruitment, safety monitoring, and our 5th consortium meeting in Helsinki. Read the full newsletter attached. Funded by the EU under Horizon Europe GA No. 101104589. #MPORTANTProject #BreastCancer #HorizonEurope #EUCancerMission #GeriatricOncology
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IMPORTANT EU Project @importanteuproject.bsky.social · 10/06/2026
The IMPORTANT Project consortium has successfully completed its 5th project meeting in Helsinki, Finland. Partners came together to review progress, exchange updates and align on the next phase of work, with discussions covering recruitment, dissemination, research outputs, pilots and ethics.
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IMPORTANT EU Project @importanteuproject.bsky.social · 11/05/2026
📢 IMPORTANT Trial Newsletter #17 is out! Updates include: ✅ 13 sites open for recruitment ✅ 118 patients included, 109 randomized ✅ Latest news on adaptive trial design and interim analysis Funded by the EU under Horizon Europe GA No. 101104589. UK participant supported by UKRI.
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IMPORTANT EU Project @importanteuproject.bsky.social · 16/03/2026
The IMPORTANT trial was presented at the EUnetCCC symposium “Innovating Cancer Care Through De-escalation Studies” in Amsterdam, contributing to discussions on improving cancer treatment through high-quality de-escalation studies #CancerResearch #BreastCancer #ClinicalTrials #HorizonEurope #EUnetCCC
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IMPORTANT EU Project @importanteuproject.bsky.social · 12/03/2026
🚀 #IMPORTANTTrial update: 101 patients enrolled so far, with 13 clinical sites currently open for recruitment. Together, we are generating evidence to improve treatment for older people with breast cancer. #BreastCancer #ClinicalTrials #GeriatricOncology #ClinicalTrials #EUfunded #HaDEA #HorizonEU
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IMPORTANT EU Project @importanteuproject.bsky.social · 12/03/2026
🎥 New video: Why dose optimisation matters for older people with advanced breast cancer. The IMPORTANT project is studying CDK4/6 inhibitor dosing strategies to improve tolerability, quality of life, and shared decision-making in treatment. #IMPORTANTproject #BreastCancer #HorizonEurope
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IMPORTANT EU Project @importanteuproject.bsky.social · 18/02/2026
The #IMPORTANTProject will join the #EUnetCCC Symposium on Cancer Treatment De-escalation 📅 5–6 March 2026 📍 NKI, Amsterdam Proud to contribute to the discussion on personalised dose optimisation for older patients with advanced HR+/HER2- breast cancer #DeEscalation #HorizonEurope #EUCancerMission
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IMPORTANT EU Project @importanteuproject.bsky.social · 11/02/2026
🎯Optimising treatment for older patients with metastatic #BreastCancer Watch here: lnkd.in/dGzPDhBv 🔬The #IMPORTANTProject aims to optimise CDK4/6 inhibitor dosing through a multinational clinical trial integrating geriatric assessment–based strategies 🎗️Older patients deserve evidence-based care
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IMPORTANT EU Project @importanteuproject.bsky.social · 04/02/2026
🎉 New paper accepted at PERSUASIVE 2026! Researchers in the EU Horizon Europe IMPORTANT Project explored why older adults hesitate to join decentralised breast cancer clinical trials. Key message: patient support must be local, personalised & human-centred. 📍 Hakodate, Japan | March 10–13, 2026
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IMPORTANT EU Project @importanteuproject.bsky.social · 02/02/2026
The IMPORTANT EU Project contributes to the Mission Cancer Cluster on Citizen Engagement, working with partner projects: LIVERATION, SAGITTARIUS, PragmaTIL, CARE1, PRIME-ROSE, DE-ESCALATE, IntReALL2020, LEGATO, IMPACT-AML, SALVOVAR, STREXIT2 #MissionCancer #CitizenEngagement #HorizonEurope #HADEA
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IMPORTANT EU Project @importanteuproject.bsky.social · 13/01/2026
Newsletter #15 The latest update is out! So far, 93 patients enrolled, all 13 sites active and preparations underway for a toxicity-driven interim analysis at 100 patients. The project continues to advance geriatric assessment–guided dosing of CDK4/6 inhibitors for older patients with breast cancer
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IMPORTANT EU Project @importanteuproject.bsky.social · 08/12/2025
The IMPORTANT project was featured in two key events! At the 36th Panhellenic Congress of Hematologists, Christiana Markou presented on the EU AI Act and its clinical impact At EUC’s AI Month 2025, she joined a round-table on bringing AI into clinical practice 🇪🇺 Funded by the EU (GA 101104589)
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IMPORTANT EU Project @importanteuproject.bsky.social · 04/12/2025
Happening today: the EU Cancer Mission Conference on Advancing cancer care: personalised treatment and innovation Researchers, clinicians, policymakers, survivors & advocates are coming together to discuss the future of personalised cancer care and precision medicine across EU link.europa.eu/pm6k4d
link.europa.eu
Register for the EU Cancer Mission Conference 2025 _Denmark
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IMPORTANT EU Project @importanteuproject.bsky.social · 31/10/2025
At #ESMO25 in Berlin 🇩🇪, Prof Laura Biganzoli presented the #IMPORTANTtrial - advancing geriatric assessment for dose optimization in older breast cancer patients A step forward in personalizing cancer care for older adults #HorizonEurope #GeriatricOncology #BreastCancer #EUfunded #ClinicalResearch
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IMPORTANT EU Project @importanteuproject.bsky.social · 29/10/2025
The #IMPORTANTproject joined the 2nd #HorizonEurope Cancer Mission “Diagnosis & Treatment” Cluster Meeting in Berlin 🇩🇪 We shared actions on #CitizenEngagement & #AddressingInequalities in cancer care highlighting how we bring science closer to people. #MissionCancer #CancerResearch #HaDEA
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IMPORTANT EU Project @importanteuproject.bsky.social · 07/10/2025
The IMPORTANT Project at the ERN 2025 in Cyprus Eunomia Ltd represented the IMPORTANT project, raising awareness on breast cancer, prevention & health literacy Through interactive quizzes, participants learned about prevention, health literacy & empathy, sharing messages of hope and solidarity 💗
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Reposted by IMPORTANT EU Project
Samuel A. Fricker @samuelfricker.bsky.social · 02/09/2025
Our REWBAH'25 presentation is ongoing @maryam-yeganeh.bsky.social #important-project #horizon @fhnwinformatik.bsky.social
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Reposted by IMPORTANT EU Project
Samuel A. Fricker @samuelfricker.bsky.social · 09/07/2025
We are very happy that our paper with Maryam Rabie Yeganeh has been accepted at REWBAH'25 👉 "One Size Doesn’t Fit All": Patient Support in a Decentralised Clinical Trial.
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IMPORTANT EU Project @importanteuproject.bsky.social · 03/09/2025
🎥 New video out! Excited to share the story of the IMPORTANT Project-the mission, clinical goals & innovative approach to optimizing CDK4/6-inhibitor treatment for older patients with advanced breast cancer ▶️ Watch the video: play.mediaflow.com/ovp/17/72DFN... 🔗 Learn more: important-project.com
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