ikauvar.bsky.social @ikauvar.bsky.social · 31/05/2025Would definitely be curious to hear your thoughts! (Doesn't have to be in a public forum though 😆, feel free to email me!). I'm a big fan of your work 120
ikauvar.bsky.social @ikauvar.bsky.social · 30/05/2025It was amazing working on this with Ethan Richman, Tony Liu, @deisseroth.bsky.social, @crodriguezmdphd.bsky.social , @samvesuna.bsky.social and many others. And we are very grateful for the incredible contributions of the participants who volunteered to be in the study. 031
ikauvar.bsky.social @ikauvar.bsky.social · 30/05/2025We hypothesize that aspects of the etiology and treatment of certain neuropsychiatric disorders may be governed by alteration of such persistence-related phenomena. 140
ikauvar.bsky.social @ikauvar.bsky.social · 30/05/2025By analogy to a piano's sustain pedal, emotional responses to sensory stimuli require the brain's "sustain pedal" to be activated, allowing signals to persist and accumulate. 130
ikauvar.bsky.social @ikauvar.bsky.social · 30/05/2025One high level takeaway is that emergence of emotional responses in mammals seems to rely on the brain's capacity to sustain persistent activity dynamics. By pharmacologically disrupting this ability of the brain, we blunt emotional responses in both humans and mice. 130
ikauvar.bsky.social @ikauvar.bsky.social · 30/05/2025Emotions are core to the human experience 😆😮🙂😊☹️😠😳😑 But how do they arise? Our brain-wide ⚡recordings in humans and mice reveal some answers @ScienceMagazine. A big team effort and debut paper from @Stanford's new Human Neural Circuitry program. bit.ly/4dEyX7Z 2279
