iiinova — where your digital self keeps evolving

Dark Matter Project @id-darkmatter-ncd.bsky.social · 27/04/2026

🔬✨ DarkMatter at #LNF26! In Vienna, François Bonnay presented DarkMatter at the @MedUni Wien booth, sharing how we explore links between infections, environment & genetics in non-communicable diseases. Events like this connect research with society and inspire future generations.

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 16/02/2026

#ECCO26 Feb 19 Stockholm, Ludwig Erlmeier (UMCG) presents: “High-throughput antibody epitope repertoire profiling links NOD2 risk-variants to specific antibody responses in Crohn’s disease.” A step toward connecting genetic risk with functional immune signatures in IBD cm.ecco-ibd.eu/cmPortal/sea...

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 10/02/2026

Rheumatoid arthritis & lupus are more than joint pain. They’re complex, systemic diseases we still don’t fully understand. By combining immunogenomics, microbiome data & antibody profiles, we aim to uncover what drives flares, treatment response & progression.

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 28/01/2026

Stakeholder engagement in complex research needs structure, time, and trust. 19 Jan, #DarkMatter joined EU-funded projects to exchange on engaging patients, PRPs, regulators, and policymakers. Key takeaways: plan early, define roles clearly, budget realistically & build internal alignment first.

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 23/01/2026

🔬 DarkMatter | Public session highlights (15 Jan) We shared how integrating immunogenetics, immune repertoires & antibody profiling helps uncover immune signatures across diseases. A strong focus on data integration, collaboration & next steps ahead. #HorizonEurope #Immunology #SystemsMedicine

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 12/01/2026

📢 ID-DarkMatter-NCD Public Session (M24) 🗓 15 Jan 2026 | 14:00–15:00 CET | 💻 Online Short pitches from all activities on immune-driven diseases, genetics & multi-omics + live Q&A. Open to external participants. 👉 Register now! bit.ly/49LWyDd

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 09/01/2026

📢 ID-DarkMatter-NCD Public Session (M24) 🗓 15 Jan 2026 | 14:00–15:00 CET | 💻 Online Join our public session for a concise update on mid-project progress across immune-driven diseases, genetics, and multi-omics research, followed by a live Q&A. 👉 Register here:https://bit.ly/49LWyDd

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 19/12/2025

🎄 Season’s Greetings from DarkMatter Thank you to all our partners and supporters for your commitment and collaboration this year. Your contributions are driving our shared progress. We look ahead to an exciting 2026, with first results on the horizon, while wishing you peaceful holidays.

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 04/12/2025

Thomas Vogl, group leader at MedUni Vienna and coordinator of the DarkMatter project, has been selected for the EMBO Young Investigator Programme. His team explores how the gut microbiome and immune system shape cancer development and therapy response-an important recognition of his innovative work

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 28/11/2025

MACHINE LEARNING & PREDICTION- Our pipeline will be open-source Science moves faster when we share. We’re preparing to release our ML pipeline on GitHub, with: 🛠️ Clear documentation 🔄 Sample datasets 🤝 FAIR, reproducible architecture We hope others build on it. We welcome collaborators.

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 21/11/2025

Ethics in healthcare ML matters. We balance performance with values: FAIR data use, transparent algorithms, clinician–patient co-design, and clear documentation. Trust isn’t just technical—it’s human. #EthicalAI #FAIRscience #ResponsibleInnovation

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 07/11/2025

🧬 Machine learning (ML) pipeline: from blood sample to prediction. Processes blood omics data to flag high-risk RA and lupus profiles. 🧪 Trained on thousands 📈 Tested across cohorts ✅ Explainable results Early detection, reimagined — with real-world clinical utility.

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 27/10/2025

Great to see the DoCTIS Atlas on therapeutic drug response across IMIDs presented at #ACR2025! 🧬 Built in the EU project doctis.eu , this work earned an Excellence in Research Award and now feeds into DarkMatter - Congratulations Toni Julià! — AI for immune prediction. #AI4Health #IMIDs

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 17/10/2025

AI for immune disease? We’re building the tools. ML is transforming how we predict and treat immune-mediated disease. At ID-DarkMatter-NCD, we’re creating explainable tools to: 🧬 Spot risk early 📊 Predict response 💡 Personalize care Transparent. Data-driven. Real patients.

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 02/10/2025

World Arthritis Day 2025 For 1 in 5 people with Rheumatoid Arthritis, treatments stop working — leaving pain, fatigue & uncertainty. MDR-RA studies why therapies fail and develops tools for personalised care. With patients, we aim to turn #RMDreams into reality.

eular.org

world-arthritis-day-2025 | EULAR

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 19/09/2025

Microbiota patterns may predict disease flares 🦠 In our #IBD research, microbes 📉 vanish before a flare & 📈 bloom during inflammation. Stool #MicrobiomeBiomarkers may give early warnings in #Crohns & #UlcerativeColitis — moving us toward predictive, not just reactive, medicine.

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 05/09/2025

Rebalancing immunity may mean restoring harmony instead of fighting inflammation. We’re testing microbiome tools: 🥦 diet, 💊 probiotics, 💩 FMT, to calm the immune system, reduce symptoms & improve regulation in IBD & MS. #FMT #MicrobiomeTherapy #DarkMatterProject

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 01/09/2025

🚀 Science gave us Antimatter and Dark Matter. Now there’s even Doesn’t Matter — with no effect on the universe. But in the DarkMatter Project, we’re all about what matters: 💡 Empowering citizens ❤️ Preventing disease 🌍 Building healthier futures #DarkMatterEU #Health #CitizenEngagement #Prevention

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 29/08/2025

Gut feeling: Your microbes might drive your immune system. Some bacteria trigger flare-ups, others calm inflammation. At ID-DarkMatter-NCD, we map the gut-immune axis to predict and prevent IBD, MS, lupus & more. #Microbiome #GutHealth #Autoimmunity #DarkMatterProject

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 21/08/2025

Autoimmunity isn’t about a “strong” immune system—it’s about a misdirected one. At ID-DarkMatter-NCD we use AI + multi-omics to design precision therapies, moving from trial-and-error medicine to tailored immunomodulation. #PrecisionMedicine

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 14/08/2025

Meet Dr Thomas Vogl, coordinator of Horizon Europe #DarkMatterEU & group leader at MedUni Vienna. At #IUIS2025 he’ll reveal how antibody repertoires unlock immune–microbiome secrets in health & disease. 🌍🔬 Learn more: loom.ly/CwagY2g

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 13/08/2025

Post 6/6 ME/CFS research is finally entering a new era — one where patient voices, large-scale data & cutting-edge science work together. #DecodeME #MECFS #Genomics #DarkMatter

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 13/08/2025

Post 5/6 🔍 Linking DecodeME’s findings to regulatory genomics could reveal why these genetic regions matter — and how to target them for diagnostics & therapies.

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 13/08/2025

Post 4/6 At Dark Matter, we’re taking this further. We study the “dark matter” of the genome — the 98% that doesn’t code for proteins — to see how it regulates immune & nervous system function in ME/CFS.

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 13/08/2025

Post 3/6 DecodeME analysed DNA from 15,000+ people with ME/CFS vs. ~260,000 controls. This is the first robust genetic evidence for ME/CFS risk — a huge step toward reducing stigma + guiding treatment research.

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 13/08/2025

Post 2/6 ME/CFS affects 67 million people worldwide, often starting after infection and causing post-exertional malaise — worsening of symptoms after even mild activity. There’s no definitive test & no effective treatment… yet.

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 13/08/2025

Post 1/6 🧬 Big news for #MECFS research. The DecodeME study — the world’s largest genetic investigation into ME/CFS — just found 8 genetic regions linked to the illness. Many involve immune response + chronic pain pathways.

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 08/08/2025

Tolerogenic vaccines don’t activate immunity—they teach it tolerance. At ID-DarkMatter-NCD, we design nanoparticle vaccines to retrain immune cells, preventing flare-ups in diseases like RA & IBD. Immune peacekeeping, not brute force. #Autoimmunity #NextGenTherapies #DarkMatterProject

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 28/07/2025

CAR-T for Autoimmune Disease? It’s real—and it’s precise. You’ve seen CAR-T revolutionise cancer care. Now it’s being tested in RA, lupus & MS. 🔬 Custom T-cells 🎯 Targeting only auto reactive cells 🔥 Less inflammation, fewer side effects No more immune sledgehammers—this is a scalpel. #DarkMatterNCD

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 18/07/2025

What if the immune system could be reprogrammed to heal itself? At ID-DarkMatter-NCD, we’re exploring immune retraining instead of suppression — using biologics, gene & cell therapy to restore balance in RA, lupus, MS & more. #Autoimmune #Immunotherapy #DarkMatterProject

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 11/07/2025

Next-gen immunotherapies at ID-DarkMatter-NCD aim to retrain the immune system to heal, not harm. 💉🦠 From CAR-T to microbiome tools, we’re tackling RA, lupus & more with precision! #Autoimmune #Immunotherapy #DarkMatterProject

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 04/07/2025

🧬 The epigenome rewrites disease risk. Stress, diet & infections can flip genes on/off without altering DNA. Can we reverse autoimmune risk by targeting epigenetics? At ID-DarkMatter-NCD, we’re finding out. #Epigenetics #ImmuneHealth

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 27/06/2025

🔬 The Power of Multi-Omics: A 360° view of disease! At ID-DarkMatter-NCD, we merge genomics, metagenomics, proteomics & metabolomics to reveal hidden drivers & enable precision medicine for IBD, MS & lupus. #MultiOmics #PrecisionMedicine #DarkMatterProject #BiomedicalInnovation

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 20/06/2025

🌟 Back from #EULAR2025 inspired! 🏅 Antonio Juliá wins Abstract Award for single-cell insights (DoCTIS) 🎤 Diane van der Woude on predicting RA before symptoms 🔬 DarkMatter’s mission—early detection & stratification—gains momentum. #PrecisionMedicine #Autoimmunity

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 12/06/2025

Big congrats to Antonio Julià (Vall d'Hebron) for winning the EULAR 2025 Abstract Award! 🏆 His DoCTIS study maps molecular variation across 6 IMIDs via single-cell RNAseq — paving the way for precision medicine! 👏 Talk: June 13, 10:30 CEST #EULAR2025 #DarkMatter

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 10/06/2025

🎤 Why is "Difficult-to-treat RA" so difficult to treat? And what can we do? 🗓 Thurs 12 June | 🕒 15:45–17:00 |Room A2 | #EULAR2025 Join #DarkMatter Partner Diane van der Woude + experts: 🧠 why some RA patients remain hard to treat 🧬 neuro-immunological approaches 🧰 case-based insights See you there!

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 06/06/2025

🔬 What if we could detect autoimmune diseases before symptoms appear? DarkMatter is pioneering early diagnosis with cutting-edge biomarkers. Early action = better outcomes. Tag someone in healthtech! #Biomarkers #EarlyDetection #DarkMatterProject

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 30/05/2025

🤖🏛️ AI is transforming medicine, but can we ensure fairness, privacy & accountability? Key concerns: ✔️ Bias in AI ✔️ Data privacy ✔️ Human validation of diagnoses Should AI diagnoses need human review? Let’s discuss! #AIethics #DarkMatterNCD #BiomedicalAI

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 23/05/2025

🦠 Could your gut hold the key to autoimmune diseases? At ID-DarkMatter-NCD, we’re exploring how gut bacteria imbalances link to IBD, MS & RA. Gut health = immune health 💙 #GutHealth #MicrobiomeScience #NCDResearch #BiomedicalInnovation

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 14/05/2025

🔬 Dark Matter & 5 Horizon Europe sibling projects—EBV-MS, BEAT-sepsis, CLARITY, POINT & COMMUTE—are uniting to study how infections drive NCDs. From EBV to COVID-19, we're sharing data, tools & science to uncover long-term impacts. #IDsinNCDs #DarkMatterProject #HorizonEurope

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 12/05/2025

Today in Vienna, ME/CFS patients protest decades of neglect. 💙 At Dark Matter, we’re working to change that—with research, AI, and hope for better care. It’s time to listen, act, and support. #MECFS #DarkMatter_HE #HopeInResearch

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Dark Matter Project @id-darkmatter-ncd.bsky.social · 09/05/2025

Precision Medicine – The Future of Chronic Disease Treatment 🎯 ID-Dark-Matter-NCD's approach paves the way for personalized care in autoimmune, inflammatory & chronic diseases—using AI to match the right treatment to your immune profile. #PrecisionMedicine #IDDarkMatterNCD #FutureOfHealth

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