Background Alzheimer’s disease (AD) is the leading cause of dementia. There are limited approved medications that delay cognitive decline or lessen neuropsychiatric symptoms. Numerous clinical trials ...

Benzodiazepines (BZDs) are commonly prescribed anxiolytic drugs that act on GABAa receptors, and can result in anterograde amnesia, or the inability to form new memories. While BZDs have been used for...

AVP and OT regulate essential physiological functions. Francesconi and Olivera-Pasilio et al., demonstrate that AVP and OT inputs excite the BNST via OTR. The OTR-expressing BNST neurons reduce anxiou...

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Cognitive impairment and memory loss are the hallmark symptoms of Alzheimer’s disease (AD), but most patients also exhibit a spectrum of noncognitive symptoms, including neuropsychiatric symptoms (NPS...