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Reposted by Hugo Diniz, MD 🇵🇹🇪🇺

Cristina Popa @nephroseeker.medsky.social · 19/10/2025

📅 Coming next week, October 23, 2025, at 5:00 PM (CEST) #Nephsky #Medsky ✨E-seminar: Interventional Nephrology- A Beginner’s Guide for Young Nephrologists 🎙️Presenting @drbarbateba.bsky.social 💬Moderator @hugodiniz.medsky.social 👉You can register here www.era-online.org/video-pages/...

era-online.org

Interventional Nephrology: A Beginner’s Guide for Young Nephrologists | ERA

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 07/06/2025

Thank you so much for attending and sharing our session 🤩 Next time, come say hi 👋

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 06/06/2025

Yeah. Hopefully the group with HFrEF gets some benefit 🤞

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 06/06/2025

Electronic Communication Committee getting their diplomas of merit at the Presidential dinner from the President Prof. @rosertorra.bsky.social #ERA25 ☺️

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 06/06/2025

Yes @lonniepyne.bsky.social was the presenter! Hopefully he might sneak in to give his thoughts on the matter #ERA25

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 06/06/2025

Also, the last author presented a new meta analysis with ACHIEVE and ALCHEMIST. Considering only studies with low risk of bias, still no evidence of positive effect @hswapnil.medsky.social

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 06/06/2025

So, about that. @pepasolerr.bsky.social asked about stratification by LVEF/echo data. Looks like only a small % had echo at baseline, but during follow up most patients got one. The author said they are going to look into that #ERA25

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 06/06/2025

Sorry, the app might have bugged on me. Are you talking about the Spironolactone trial? This replies are under the sglt2i aki analysis

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 06/06/2025

Me neither, but the study was well designed to answer the question. Regarding HF, I don't think so, but they basically used all the Empagliflozin trials for the analysis

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 06/06/2025

Prof Anders made a case for the (im)balance between workload (hyperfiltration) and nephron mass as the key interaction DM is a risk factor - there are no diabetic HF or diabetic cerebral vascular disease. Most cases are probably multifactorial HTN ckd probably doesnt exist and most are genetic

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Reposted by Hugo Diniz, MD 🇵🇹🇪🇺

Jayana Devathasan @jyndvthsn.bsky.social · 06/06/2025

Vlado Perkovic discussing Sibeprenlimab (APRIL binder) at Late Breaking Clinic Trials II at #era25. Great to see Oceanians (Aus/NZers) on stage!

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 06/06/2025

Wasn't aware of that, thanks! Dr. Walsh mentioned it is already accepted for publication in a major journal #ERA25

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 06/06/2025

ACHIEVE trial - Spironolactone in Hemodialysis stopped early... due to futility 😢 I had some hopes for this one. #ERA25

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 06/06/2025

iSGLT2 effects on Acute Kidney Outcomes #ERA25 ✅ Clear protective effects for AKI ❌ No extra risk of AKI events during the acute eGFR dip

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 06/06/2025

Sibeprenlimab in IgA Nephropathy #ERA25 * Data presented is the 9-month reduction in proteinuria

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 06/06/2025

Visionary interim analysis! #ERA25 massive reduction in proteinuria after 1 year of treatment

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Reposted by Hugo Diniz, MD 🇵🇹🇪🇺

Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 05/06/2025

I agree. Clinically it doesn’t hurt to try a flozin if a patient with diabetes or HF is on an MRA and has hyperkalemia since flozins are clearly indicated in that patient population But don’t bank on them to fix the issue - it’s a small effect even if true! #ERA25 #NephSky

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 05/06/2025

Prof. Anders starting with a banger Diabetic Kidney Disease and Hypertensive Kidney Disease don't exist! 😱 #ERA25

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 05/06/2025

Ah, yes. By the way they presented it looked significant. But, still a small decrease is much better than an increased risk 😁

media.tenor.com

a glass half full of blue liquid on a gray background

ALT: a glass half full of blue liquid on a gray background

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 05/06/2025

Yes, the lack of morphological and hemodynamic data about the AVGs was also puzzling #ERA25

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Reposted by Hugo Diniz, MD 🇵🇹🇪🇺

Alex Meraz @nephroguy.bsky.social · 05/06/2025

@kevinyau.bsky.social GLP1 agonist master Jedi presenting at #ERA25. 💉GLP1 agonist reduce ED visits and hospitalizations!!! 📉Awesome methods. Best of the session: 💊DDP4 for comparison, IPTW, ICES data. Ticking all the right boxes (EPI nerd). 💊Only 40% on SGLT2i!!! We should flozinate more!!!

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Reposted by Hugo Diniz, MD 🇵🇹🇪🇺

Swapnil Hiremath 🍁🇨🇦 @hswapnil.medsky.social · 05/06/2025

The first #ERA25 simultaneous pub CONFIDENCE trial of empagliflozin + finerenone in N = 579 Greater reduction in ACR and BP Note the impressive GFR dip www.nejm.org/doi/full/10....

Urinary Albumin-to-Creatinine Ratio, Serum Potassium Level, Estimated Glomerular Filtration Rate, and Systolic Blood Pressure over Time.

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 05/06/2025

They are lower, both investigator-reported and K+ > 5.5 right?

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 05/06/2025

Yes! Thank you. Probably too cautious #ERA25 P.S. Love your handle

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 05/06/2025

#CONFIDENCE Simultaneous publication in @nejm.org www.nejm.org/doi/full/10....

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 05/06/2025

#CONFIDENCE Finerenone + Empagliflozin 52% drop in UACR at 180 days; More patients achieve the therapeutic targets Combination with less HiperK+! #ERA25

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 04/06/2025

Great game by Vitinha and Conceição! 🇵🇹 2 x 1 🇩🇪 and into the final! Nice excuse to enjoy some beer with friends at #ERA25 🍻

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 04/06/2025

Starting of #ERA25 by teaching some tips and tricks about kidney biopsies! Photo courtesy of @franvalga.bsky.social

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 04/06/2025

And tomorrow, the Sun will shine even brighter! #ERA25

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Reposted by Hugo Diniz, MD 🇵🇹🇪🇺

josh farkas 💊 @pulmcrit.bsky.social · 03/06/2025

amiloride is such a great drug if someone diuresed with furosemide +/- thiazide suddenly dumps 3 liters of urine, their potassium goes to 2.5 with amiloride on board, the potassium just stays stable. someone needs to do an RCT proving that amiloride avoids dangerous hypokalemia 🙏

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Hugo Diniz, MD 🇵🇹🇪🇺 @hugodiniz.medsky.social · 03/06/2025

So, who's going to Vienna for #ERA25? 🇦🇹 Seems like a nice event to transition to BlueSky! Thank you to everyone that followed me back!

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